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Human cytomegalovirus UL76 elicits novel aggresome formation via interaction with S5a of the ubiquitin proteasome system.

Lin SR, Jiang MJ, Wang HH, Hu CH, Hsu MS, Hsi E, Duh CY, Wang SK.

J Virol. 2013 Nov;87(21):11562-78. doi: 10.1128/JVI.01568-13. Epub 2013 Aug 21.


Human cytomegalovirus gene UL76 induces IL-8 expression through activation of the DNA damage response.

Costa H, Nascimento R, Sinclair J, Parkhouse RM.

PLoS Pathog. 2013 Sep;9(9):e1003609. doi: 10.1371/journal.ppat.1003609. Epub 2013 Sep 12.


VWA domain of S5a restricts the ability to bind ubiquitin and Ubl to the 26S proteasome.

Piterman R, Braunstein I, Isakov E, Ziv T, Navon A, Cohen S, Stanhill A.

Mol Biol Cell. 2014 Dec 15;25(25):3988-98. doi: 10.1091/mbc.E13-11-0697. Epub 2014 Oct 15.


The ubiquitin-interacting motif of 26S proteasome subunit S5a induces A549 lung cancer cell death.

Elangovan M, Choi ES, Jang BG, Kim MS, Yoo YJ.

Biochem Biophys Res Commun. 2007 Dec 14;364(2):226-30. Epub 2007 Oct 11.


The human cytomegalovirus UL76 gene regulates the level of expression of the UL77 gene.

Isomura H, Stinski MF, Murata T, Nakayama S, Chiba S, Akatsuka Y, Kanda T, Tsurumi T.

PLoS One. 2010 Jul 30;5(7):e11901. doi: 10.1371/journal.pone.0011901.


Aggresome formation.

Corboy MJ, Thomas PJ, Wigley WC.

Methods Mol Biol. 2005;301:305-27.


A High-Content Screening Assay for the Discovery of Novel Proteasome Inhibitors from Formosan Soft Corals.

Ling XH, Wang SK, Huang YH, Huang MJ, Duh CY.

Mar Drugs. 2018 Oct 21;16(10). pii: E395. doi: 10.3390/md16100395.


The UBL domain of PLIC-1 regulates aggresome formation.

Heir R, Ablasou C, Dumontier E, Elliott M, Fagotto-Kaufmann C, Bedford FK.

EMBO Rep. 2006 Dec;7(12):1252-8. Epub 2006 Nov 3.


Human cytomegalovirus UL76 induces chromosome aberrations.

Siew VK, Duh CY, Wang SK.

J Biomed Sci. 2009 Nov 25;16:107. doi: 10.1186/1423-0127-16-107.


Interaction of HPV E6 oncoproteins with specific proteasomal subunits.

Tomaić V, Ganti K, Pim D, Bauer C, Blattner C, Banks L.

Virology. 2013 Nov;446(1-2):389-96. doi: 10.1016/j.virol.2013.08.016. Epub 2013 Sep 17.


Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13.

Elangovan M, Oh C, Sukumaran L, Wójcik C, Yoo YJ.

Biochem Biophys Res Commun. 2010 May 28;396(2):425-8. doi: 10.1016/j.bbrc.2010.04.108. Epub 2010 Apr 22.


Inhibition of human cytomegalovirus replication via peptide aptamers directed against the nonconventional nuclear localization signal of the essential viral replication factor pUL84.

Kaiser N, Lischka P, Wagenknecht N, Stamminger T.

J Virol. 2009 Nov;83(22):11902-13. doi: 10.1128/JVI.01378-09. Epub 2009 Sep 9.


Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.

Rechter S, Scott GM, Eickhoff J, Zielke K, Auerochs S, Müller R, Stamminger T, Rawlinson WD, Marschall M.

J Biol Chem. 2009 Mar 27;284(13):8605-13. doi: 10.1074/jbc.M805693200. Epub 2009 Jan 29.


Granzyme M targets host cell hnRNP K that is essential for human cytomegalovirus replication.

van Domselaar R, de Poot SA, Remmerswaal EB, Lai KW, ten Berge IJ, Bovenschen N.

Cell Death Differ. 2013 Mar;20(3):419-29. doi: 10.1038/cdd.2012.132. Epub 2012 Oct 26.


Triggering aggresome formation. Dissecting aggresome-targeting and aggregation signals in synphilin 1.

Zaarur N, Meriin AB, Gabai VL, Sherman MY.

J Biol Chem. 2008 Oct 10;283(41):27575-84. doi: 10.1074/jbc.M802216200. Epub 2008 Jul 17.

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