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Items: 1 to 20 of 321

1.

Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis.

Lanz TV, Becker S, Osswald M, Bittner S, Schuhmann MK, Opitz CA, Gaikwad S, Wiestler B, Litzenburger UM, Sahm F, Ott M, Iwantscheff S, Grabitz C, Mittelbronn M, von Deimling A, Winkler F, Meuth SG, Wick W, Platten M.

Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14735-40. doi: 10.1073/pnas.1302569110. Epub 2013 Aug 19.

2.

Immune-related GTPase Irgm1 exacerbates experimental auto-immune encephalomyelitis by promoting the disruption of blood-brain barrier and blood-cerebrospinal fluid barrier.

Wang C, Wang C, Dong H, Wu XM, Wang C, Xia F, Li G, Jia X, He S, Jiang X, Li H, Xu H.

Mol Immunol. 2013 Jan;53(1-2):43-51. doi: 10.1016/j.molimm.2012.06.009. Epub 2012 Jul 13.

PMID:
22796503
3.

The protective effects of bioactive (RS)-glucoraphanin on the permeability of the mice blood-brain barrier following experimental autoimmune encephalomyelitis.

Giacoppo S, Galuppo M, Iori R, De Nicola GR, Bramanti P, Mazzon E.

Eur Rev Med Pharmacol Sci. 2014;18(2):194-204.

4.

Effects of fumaric acid esters on blood-brain barrier tight junction proteins.

Bénardais K, Pul R, Singh V, Skripuletz T, Lee DH, Linker RA, Gudi V, Stangel M.

Neurosci Lett. 2013 Oct 25;555:165-70. doi: 10.1016/j.neulet.2013.09.038. Epub 2013 Sep 26.

PMID:
24076006
5.

Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis.

Pfeiffer F, Schäfer J, Lyck R, Makrides V, Brunner S, Schaeren-Wiemers N, Deutsch U, Engelhardt B.

Acta Neuropathol. 2011 Nov;122(5):601-14. doi: 10.1007/s00401-011-0883-2. Epub 2011 Oct 9.

6.

Blockade of the kinin receptor B1 protects from autoimmune CNS disease by reducing leukocyte trafficking.

Göbel K, Pankratz S, Schneider-Hohendorf T, Bittner S, Schuhmann MK, Langer HF, Stoll G, Wiendl H, Kleinschnitz C, Meuth SG.

J Autoimmun. 2011 Mar;36(2):106-14. doi: 10.1016/j.jaut.2010.11.004. Epub 2011 Jan 8.

PMID:
21216565
7.

Matrix metalloproteinase-2 and -9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins.

Feng S, Cen J, Huang Y, Shen H, Yao L, Wang Y, Chen Z.

PLoS One. 2011;6(8):e20599. doi: 10.1371/journal.pone.0020599. Epub 2011 Aug 17. Erratum in: PLoS One. 2011;6(8). doi: 10.1371/annotation/716c0fb2-dbdd-4da5-ad8a-d2b1cdac4ec6.

8.

Baicalin reduces the permeability of the blood-brain barrier during hypoxia in vitro by increasing the expression of tight junction proteins in brain microvascular endothelial cells.

Zhu H, Wang Z, Xing Y, Gao Y, Ma T, Lou L, Lou J, Gao Y, Wang S, Wang Y.

J Ethnopharmacol. 2012 Jun 1;141(2):714-20. doi: 10.1016/j.jep.2011.08.063. Epub 2011 Sep 3.

PMID:
21920425
9.

Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier.

Abadier M, Haghayegh Jahromi N, Cardoso Alves L, Boscacci R, Vestweber D, Barnum S, Deutsch U, Engelhardt B, Lyck R.

Eur J Immunol. 2015 Apr;45(4):1043-58. doi: 10.1002/eji.201445125. Epub 2015 Jan 23.

11.

Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme.

Wolburg H, Wolburg-Buchholz K, Kraus J, Rascher-Eggstein G, Liebner S, Hamm S, Duffner F, Grote EH, Risau W, Engelhardt B.

Acta Neuropathol. 2003 Jun;105(6):586-92. Epub 2003 Feb 25.

PMID:
12734665
12.
13.

Cellular mechanisms of IL-17-induced blood-brain barrier disruption.

Huppert J, Closhen D, Croxford A, White R, Kulig P, Pietrowski E, Bechmann I, Becher B, Luhmann HJ, Waisman A, Kuhlmann CR.

FASEB J. 2010 Apr;24(4):1023-34. doi: 10.1096/fj.09-141978. Epub 2009 Nov 25.

PMID:
19940258
14.

Transient alterations of the blood-brain barrier tight junction and receptor potential channel gene expression by chlorpyrifos.

Li W, Ehrich M.

J Appl Toxicol. 2013 Oct;33(10):1187-91. doi: 10.1002/jat.2762. Epub 2012 May 18.

PMID:
22611033
15.

Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5.

Ramirez SH, Fan S, Dykstra H, Rom S, Mercer A, Reichenbach NL, Gofman L, Persidsky Y.

PLoS One. 2013;8(2):e55972. doi: 10.1371/journal.pone.0055972. Epub 2013 Feb 13.

16.

Interferon-γ safeguards blood-brain barrier during experimental autoimmune encephalomyelitis.

Ni C, Wang C, Zhang J, Qu L, Liu X, Lu Y, Yang W, Deng J, Lorenz D, Gao P, Meng Q, Yan X, Blasig IE, Qin Z.

Am J Pathol. 2014 Dec;184(12):3308-20. doi: 10.1016/j.ajpath.2014.08.019. Epub 2014 Oct 7.

PMID:
25307346
17.

DAB389IL-2 suppresses autoimmune inflammation in the CNS and inhibits T cell-mediated lysis of glial target cells.

Bhopale MK, Hilliard B, Constantinescu CS, Fujioka T, Ventura E, Phillips SM, Rostami A.

Exp Mol Pathol. 2014 Feb;96(1):108-17. doi: 10.1016/j.yexmp.2013.07.004. Epub 2013 Jul 17.

PMID:
23872438
18.

Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis.

Pittet CL, Newcombe J, Prat A, Arbour N.

J Neuroinflammation. 2011 Nov 8;8:155. doi: 10.1186/1742-2094-8-155.

19.

Lentivirus-mediated estrogen receptor α overexpression in the central nervous system ameliorates experimental autoimmune encephalomyelitis in mice.

Hu X, Qin X.

Int J Mol Med. 2013 May;31(5):1209-21. doi: 10.3892/ijmm.2013.1306. Epub 2013 Mar 15.

PMID:
23525227
20.

Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis.

Ifergan I, Wosik K, Cayrol R, Kébir H, Auger C, Bernard M, Bouthillier A, Moumdjian R, Duquette P, Prat A.

Ann Neurol. 2006 Jul;60(1):45-55.

PMID:
16729291

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