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Items: 1 to 20 of 87

1.

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.

He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, Whistler JL, Levine B.

Cell. 2013 Aug 29;154(5):1085-99. doi: 10.1016/j.cell.2013.07.035. Epub 2013 Aug 15.

2.

Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.

Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M.

Prog Neurobiol. 2013 Jul-Aug;106-107:33-54. doi: 10.1016/j.pneurobio.2013.06.002. Epub 2013 Jul 1. Review.

PMID:
23827971
3.

Differential interactions between Beclin 1 and Bcl-2 family members.

Erlich S, Mizrachy L, Segev O, Lindenboim L, Zmira O, Adi-Harel S, Hirsch JA, Stein R, Pinkas-Kramarski R.

Autophagy. 2007 Nov-Dec;3(6):561-8. Epub 2007 Jul 8.

PMID:
17643073
4.

Regulation of plasma membrane receptors by a new autophagy-related BECN/Beclin family member.

Zhang W, He C.

Autophagy. 2014 Aug;10(8):1472-3. doi: 10.4161/auto.29414. Epub 2014 Jun 12.

5.

Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis.

Dong X, Cheng A, Zou Z, Yang YS, Sumpter RM Jr, Huang CL, Bhagat G, Virgin HW, Lira SA, Levine B.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):2994-9. doi: 10.1073/pnas.1601860113. Epub 2016 Feb 29.

6.

Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy.

Fogel AI, Dlouhy BJ, Wang C, Ryu SW, Neutzner A, Hasson SA, Sideris DP, Abeliovich H, Youle RJ.

Mol Cell Biol. 2013 Sep;33(18):3675-88. doi: 10.1128/MCB.00079-13. Epub 2013 Jul 22.

7.

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2.

Maejima Y, Kyoi S, Zhai P, Liu T, Li H, Ivessa A, Sciarretta S, Del Re DP, Zablocki DK, Hsu CP, Lim DS, Isobe M, Sadoshima J.

Nat Med. 2013 Nov;19(11):1478-88. doi: 10.1038/nm.3322. Epub 2013 Oct 20.

8.

Functional interaction of heat shock protein 90 and Beclin 1 modulates Toll-like receptor-mediated autophagy.

Xu C, Liu J, Hsu LC, Luo Y, Xiang R, Chuang TH.

FASEB J. 2011 Aug;25(8):2700-10. doi: 10.1096/fj.10-167676. Epub 2011 May 4.

9.

Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1.

Shi CS, Kehrl JH.

Autophagy. 2010 Oct;6(7):986-7. doi: 10.4161/auto.6.7.13288. Epub 2010 Oct 9.

10.

Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11.

Sinha S, Colbert CL, Becker N, Wei Y, Levine B.

Autophagy. 2008 Nov;4(8):989-97. Epub 2008 Nov 18. Erratum in: Autophagy.2009 Feb;5(2):284.

11.

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.

Itakura E, Kishi C, Inoue K, Mizushima N.

Mol Biol Cell. 2008 Dec;19(12):5360-72. doi: 10.1091/mbc.E08-01-0080. Epub 2008 Oct 8.

12.

Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment.

Adi-Harel S, Erlich S, Schmukler E, Cohen-Kedar S, Segev O, Mizrachy L, Hirsch JA, Pinkas-Kramarski R.

J Cell Biochem. 2010 Aug 1;110(5):1262-71. doi: 10.1002/jcb.22642.

PMID:
20564222
13.

Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels.

Zhong Y, Morris DH, Jin L, Patel MS, Karunakaran SK, Fu YJ, Matuszak EA, Weiss HL, Chait BT, Wang QJ.

J Biol Chem. 2014 Sep 19;289(38):26021-37. doi: 10.1074/jbc.M114.561134. Epub 2014 Aug 1.

15.

Inhibition of autophagy by TAB2 and TAB3.

Criollo A, Niso-Santano M, Malik SA, Michaud M, Morselli E, MariƱo G, Lachkar S, Arkhipenko AV, Harper F, Pierron G, Rain JC, Ninomiya-Tsuji J, Fuentes JM, Lavandero S, Galluzzi L, Maiuri MC, Kroemer G.

EMBO J. 2011 Nov 11;30(24):4908-20. doi: 10.1038/emboj.2011.413.

16.

Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis.

Zhu Y, Zhao L, Liu L, Gao P, Tian W, Wang X, Jin H, Xu H, Chen Q.

Protein Cell. 2010 May;1(5):468-77. doi: 10.1007/s13238-010-0048-4. Epub 2010 Jun 4.

17.

Beclin-1-interacting autophagy protein Atg14L targets the SNARE-associated protein Snapin to coordinate endocytic trafficking.

Kim HJ, Zhong Q, Sheng ZH, Yoshimori T, Liang C, Jung JU.

J Cell Sci. 2012 Oct 15;125(Pt 20):4740-50. doi: 10.1242/jcs.100339. Epub 2012 Jul 13.

18.

Common and divergent functions of Beclin 1 and Beclin 2.

Galluzzi L, Kroemer G.

Cell Res. 2013 Dec;23(12):1341-2. doi: 10.1038/cr.2013.129. Epub 2013 Sep 10.

19.

Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability.

Zou J, Yue F, Jiang X, Li W, Yi J, Liu L.

Biochem J. 2013 Sep 15;454(3):447-57. doi: 10.1042/BJ20130306.

20.

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation.

Wei Y, An Z, Zou Z, Sumpter R, Su M, Zang X, Sinha S, Gaestel M, Levine B.

Elife. 2015 Feb 18;4. doi: 10.7554/eLife.05289.

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