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Items: 1 to 20 of 116

1.

Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals.

Rodrigues RM, De Kock J, Branson S, Vinken M, Meganathan K, Chaudhari U, Sachinidis A, Govaere O, Roskams T, De Boe V, Vanhaecke T, Rogiers V.

Stem Cells Dev. 2014 Jan 1;23(1):44-55. doi: 10.1089/scd.2013.0157. Epub 2013 Sep 21.

2.

In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.

Rodrigues RM, Branson S, De Boe V, Sachinidis A, Rogiers V, De Kock J, Vanhaecke T.

Arch Toxicol. 2016 Mar;90(3):677-89. doi: 10.1007/s00204-015-1483-z. Epub 2015 Feb 26.

PMID:
25716160
3.

Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems.

Rodrigues RM, Heymans A, De Boe V, Sachinidis A, Chaudhari U, Govaere O, Roskams T, Vanhaecke T, Rogiers V, De Kock J.

Toxicol Lett. 2016 Jan 5;240(1):50-9. doi: 10.1016/j.toxlet.2015.10.014. Epub 2015 Oct 20.

PMID:
26497421
4.

A liver-derived rat epithelial cell line from biliary origin acquires hepatic functions upon sequential exposure to hepatogenic growth factors and cytokines.

De Kock J, Snykers S, Branson S, Jagtap S, Gaspar JA, Sachinidis A, Vanhaecke T, Rogiers V.

Curr Med Chem. 2012;19(26):4523-33.

PMID:
22934771
5.

Characterization and hepatic differentiation of skin-derived precursors from adult foreskin by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development.

De Kock J, Vanhaecke T, Biernaskie J, Rogiers V, Snykers S.

Toxicol In Vitro. 2009 Dec;23(8):1522-7. doi: 10.1016/j.tiv.2009.08.014. Epub 2009 Aug 29.

PMID:
19720137
6.

Efficient generation of functional hepatocyte-like cells from human fetal hepatic progenitor cells in vitro.

Zhang W, Li W, Liu B, Wang P, Li W, Zhang H.

J Cell Physiol. 2012 May;227(5):2051-8. doi: 10.1002/jcp.22934.

PMID:
21751216
7.

Identification of potential biomarkers of hepatitis B-induced acute liver failure using hepatic cells derived from human skin precursors.

Rodrigues RM, Sachinidis A, De Boe V, Rogiers V, Vanhaecke T, De Kock J.

Toxicol In Vitro. 2015 Sep;29(6):1231-9. doi: 10.1016/j.tiv.2014.10.012. Epub 2014 Oct 24.

PMID:
25458485
8.
9.

Proliferation of hepatocyte progenitor cells isolated from adult human livers in serum-free medium.

Sasaki K, Kon J, Mizuguchi T, Chen Q, Ooe H, Oshima H, Hirata K, Mitaka T.

Cell Transplant. 2008;17(10-11):1221-30.

PMID:
19181216
10.

Sequential exposure to cytokines reflecting embryogenesis: the key for in vitro differentiation of adult bone marrow stem cells into functional hepatocyte-like cells.

Snykers S, Vanhaecke T, Papeleu P, Luttun A, Jiang Y, Vander Heyden Y, Verfaillie C, Rogiers V.

Toxicol Sci. 2006 Dec;94(2):330-41; discussion 235-9. Epub 2006 Jul 13.

PMID:
16840566
11.

Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project.

Mandenius CF, Andersson TB, Alves PM, Batzl-Hartmann C, Björquist P, Carrondo MJ, Chesne C, Coecke S, Edsbagge J, Fredriksson JM, Gerlach JC, Heinzle E, Ingelman-Sundberg M, Johansson I, Küppers-Munther B, Müller-Vieira U, Noor F, Zeilinger K.

Altern Lab Anim. 2011 May;39(2):147-71.

PMID:
21639679
12.

Direct hepatic differentiation of mouse embryonic stem cells induced by valproic acid and cytokines.

Dong XJ, Zhang GR, Zhou QJ, Pan RL, Chen Y, Xiang LX, Shao JZ.

World J Gastroenterol. 2009 Nov 7;15(41):5165-75.

13.

Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.

Gómez-Lechón MJ, Tolosa L.

Arch Toxicol. 2016 Sep;90(9):2049-61. doi: 10.1007/s00204-016-1756-1. Epub 2016 Jun 20. Review.

PMID:
27325232
14.

In vitro screening system for hepatotoxicity: comparison of bone-marrow-derived mesenchymal stem cells and Placenta-derived stem cells.

Lee HJ, Cha KE, Hwang SG, Kim JK, Kim GJ.

J Cell Biochem. 2011 Jan;112(1):49-58. doi: 10.1002/jcb.22728.

PMID:
20524208
15.

Murine embryonic stem cell-derived hepatic progenitor cells engraft in recipient livers with limited capacity of liver tissue formation.

Sharma AD, Cantz T, Vogel A, Schambach A, Haridass D, Iken M, Bleidissel M, Manns MP, Schöler HR, Ott M.

Cell Transplant. 2008;17(3):313-23.

PMID:
18522234
16.

[Effects of growth factors and extracellular matrix on proliferation and differentiation of fetal liver progenitor cell in vitro].

Qin AL, Zhou XQ, Yu H, Xie Q, Zhang W, Guo Q.

Zhonghua Gan Zang Bing Za Zhi. 2004 Jul;12(7):406-9. Chinese.

PMID:
15268804
17.

Chemically induced hepatotoxicity in human stem cell-induced hepatocytes compared with primary hepatocytes and HepG2.

Kang SJ, Lee HM, Park YI, Yi H, Lee H, So B, Song JY, Kang HG.

Cell Biol Toxicol. 2016 Oct;32(5):403-17. doi: 10.1007/s10565-016-9342-0. Epub 2016 Jun 11.

PMID:
27287938
18.

Enhanced Metabolizing Activity of Human ES Cell-Derived Hepatocytes Using a 3D Culture System with Repeated Exposures to Xenobiotics.

Kim JH, Jang YJ, An SY, Son J, Lee J, Lee G, Park JY, Park HJ, Hwang DY, Kim JH, Han J.

Toxicol Sci. 2015 Sep;147(1):190-206. doi: 10.1093/toxsci/kfv121. Epub 2015 Jun 17. Erratum in: Toxicol Sci. 2016 Jan;149(1):269.

PMID:
26089346
19.

Isolation of epithelial cells with hepatobiliary phenotype.

Castorina S, Luca T, Torrisi A, Privitera G, Panebianco M.

Ital J Anat Embryol. 2008 Oct-Dec;113(4):199-207.

PMID:
19507460
20.

Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells.

Taléns-Visconti R, Bonora A, Jover R, Mirabet V, Carbonell F, Castell JV, Gómez-Lechón MJ.

World J Gastroenterol. 2006 Sep 28;12(36):5834-45.

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