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Items: 1 to 20 of 140

1.

Neonatal Fc receptor and its role in the absorption, distribution, metabolism and excretion of immunoglobulin G-based biotherapeutics.

Giragossian C, Clark T, Piché-Nicholas N, Bowman CJ.

Curr Drug Metab. 2013 Sep;14(7):764-90. Review.

PMID:
23952252
2.

FcRn: the neonatal Fc receptor comes of age.

Roopenian DC, Akilesh S.

Nat Rev Immunol. 2007 Sep;7(9):715-25. Review.

PMID:
17703228
3.
4.

[Neonatal Fc receptor, key control of immunoglobulins biodistribution].

Magdelaine-Beuzelin C, Ohresser M, Watier H.

Med Sci (Paris). 2009 Dec;25(12):1053-6. doi: 10.1051/medsci/200925121053. Review. French.

5.

Qualification of a homogeneous cell-based neonatal Fc receptor (FcRn) binding assay and its application to studies on Fc functionality of IgG-based therapeutics.

Mathur A, Arora T, Liu L, Crouse-Zeineddini J, Mukku V.

J Immunol Methods. 2013 Apr 30;390(1-2):81-91. doi: 10.1016/j.jim.2013.01.011.

PMID:
23384837
6.

Neonatal Fc receptor and IgG-based therapeutics.

Kuo TT, Aveson VG.

MAbs. 2011 Sep-Oct;3(5):422-30. doi: 10.4161/mabs.3.5.16983. Review.

7.

The multiple facets of FcRn in immunity.

Stapleton NM, Einarsdóttir HK, Stemerding AM, Vidarsson G.

Immunol Rev. 2015 Nov;268(1):253-68. doi: 10.1111/imr.12331. Review.

PMID:
26497526
8.

The immunologic functions of the neonatal Fc receptor for IgG.

Rath T, Kuo TT, Baker K, Qiao SW, Kobayashi K, Yoshida M, Roopenian D, Fiebiger E, Lencer WI, Blumberg RS.

J Clin Immunol. 2013 Jan;33 Suppl 1:S9-17. doi: 10.1007/s10875-012-9768-y. Review.

9.

A strategy for bacterial production of a soluble functional human neonatal Fc receptor.

Andersen JT, Justesen S, Berntzen G, Michaelsen TE, Lauvrak V, Fleckenstein B, Buus S, Sandlie I.

J Immunol Methods. 2008 Feb 29;331(1-2):39-49.

PMID:
18155020
10.

Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR.

Suzuki T, Ishii-Watabe A, Tada M, Kobayashi T, Kanayasu-Toyoda T, Kawanishi T, Yamaguchi T.

J Immunol. 2010 Feb 15;184(4):1968-76. doi: 10.4049/jimmunol.0903296.

11.

Are endosomal trafficking parameters better targets for improving mAb pharmacokinetics than FcRn binding affinity?

Gurbaxani B, Dostalek M, Gardner I.

Mol Immunol. 2013 Dec;56(4):660-74. doi: 10.1016/j.molimm.2013.05.008. Review.

PMID:
23917469
12.

Fc-mediated transport of nanoparticles across airway epithelial cell layers.

Vllasaliu D, Alexander C, Garnett M, Eaton M, Stolnik S.

J Control Release. 2012 Mar 28;158(3):479-86. doi: 10.1016/j.jconrel.2011.12.009.

PMID:
22200577
13.
14.

Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine.

Ladinsky MS, Huey-Tubman KE, Bjorkman PJ.

Mol Biol Cell. 2012 Jul;23(13):2537-45. doi: 10.1091/mbc.E12-02-0093.

15.

Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization.

Foss S, Grevys A, Sand KM, Bern M, Blundell P, Michaelsen TE, Pleass RJ, Sandlie I, Andersen JT.

J Control Release. 2016 Feb 10;223:42-52. doi: 10.1016/j.jconrel.2015.12.033.

PMID:
26718855
16.

N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.

Kuo TT, de Muinck EJ, Claypool SM, Yoshida M, Nagaishi T, Aveson VG, Lencer WI, Blumberg RS.

J Biol Chem. 2009 Mar 27;284(13):8292-300. doi: 10.1074/jbc.M805877200.

17.

FcRn-mediated antibody transport across epithelial cells revealed by electron tomography.

He W, Ladinsky MS, Huey-Tubman KE, Jensen GJ, McIntosh JR, Björkman PJ.

Nature. 2008 Sep 25;455(7212):542-6. doi: 10.1038/nature07255.

18.
19.

Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding.

Martin WL, West AP Jr, Gan L, Bjorkman PJ.

Mol Cell. 2001 Apr;7(4):867-77.

20.

Characterization of the rabbit neonatal Fc receptor (FcRn) and analyzing the immunophenotype of the transgenic rabbits that overexpresses FcRn.

Catunda Lemos AP, Cervenak J, Bender B, Hoffmann OI, Baranyi M, Kerekes A, Farkas A, Bosze Z, Hiripi L, Kacskovics I.

PLoS One. 2012;7(1):e28869. doi: 10.1371/journal.pone.0028869.

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