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Items: 1 to 20 of 159


Contribution of 32 GWAS-identified common variants to severe obesity in European adults referred for bariatric surgery.

Mägi R, Manning S, Yousseif A, Pucci A, Santini F, Karra E, Querci G, Pelosini C, McCarthy MI, Lindgren CM, Batterham RL.

PLoS One. 2013 Aug 7;8(8):e70735. doi: 10.1371/journal.pone.0070735. eCollection 2013.


Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4R genes to obesity in Mexican children.

Mejía-Benítez A, Klünder-Klünder M, Yengo L, Meyre D, Aradillas C, Cruz E, Pérez-Luque E, Malacara JM, Garay ME, Peralta-Romero J, Flores-Huerta S, García-Mena J, Froguel P, Cruz M, Bonnefond A.

BMC Med Genet. 2013 Feb 1;14:21. doi: 10.1186/1471-2350-14-21.


A single FTO gene variant rs9939609 is associated with body weight evolution in a multiethnic extremely obese population that underwent bariatric surgery.

Rodrigues GK, Resende CM, Durso DF, Rodrigues LA, Silva JL, Reis RC, Pereira SS, Ferreira DC, Franco GR, Alvarez-Leite J.

Nutrition. 2015 Nov-Dec;31(11-12):1344-50. doi: 10.1016/j.nut.2015.05.020. Epub 2015 Jun 25.


The contribution of FTO and UCP-1 SNPs to extreme obesity, diabetes and cardiovascular risk in Brazilian individuals.

Ramos AV, Bastos-Rodrigues L, Resende BA, Friedman E, Campanha-Versiani L, Miranda DM, Sarquis M, De Marco L.

BMC Med Genet. 2012 Nov 7;13:101. doi: 10.1186/1471-2350-13-101.


Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population.

Robiou-du-Pont S, Bonnefond A, Yengo L, Vaillant E, Lobbens S, Durand E, Weill J, Lantieri O, Balkau B, Charpentier G, Marre M, Froguel P, Meyre D.

Int J Obes (Lond). 2013 Jul;37(7):980-5. doi: 10.1038/ijo.2012.175. Epub 2012 Oct 23.


Implication of European-derived adiposity loci in African Americans.

Hester JM, Wing MR, Li J, Palmer ND, Xu J, Hicks PJ, Roh BH, Norris JM, Wagenknecht LE, Langefeld CD, Freedman BI, Bowden DW, Ng MC.

Int J Obes (Lond). 2012 Mar;36(3):465-73. doi: 10.1038/ijo.2011.131. Epub 2011 Jul 12.


Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.

Holzapfel C, Grallert H, Huth C, Wahl S, Fischer B, Döring A, Rückert IM, Hinney A, Hebebrand J, Wichmann HE, Hauner H, Illig T, Heid IM.

Int J Obes (Lond). 2010 Oct;34(10):1538-45. doi: 10.1038/ijo.2010.79. Epub 2010 Apr 13.


Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study.

Wang HJ, Hinney A, Song JY, Scherag A, Meng XR, Grallert H, Illig T, Hebebrand J, Wang Y, Ma J.

BMC Med Genet. 2016 Jan 22;17:7. doi: 10.1186/s12881-016-0268-4.


Frequencies of obesity susceptibility alleles among ethnically and racially diverse bariatric patient populations.

Parikh M, Hetherington J, Sheth S, Seiler J, Ostrer H, Gerhard G, Wood C, Still C.

Surg Obes Relat Dis. 2013 May-Jun;9(3):436-41. doi: 10.1016/j.soard.2012.04.004. Epub 2012 May 8.


Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty.

Wang J, Mei H, Chen W, Jiang Y, Sun W, Li F, Fu Q, Jiang F.

Int J Obes (Lond). 2012 Apr;36(4):542-7. doi: 10.1038/ijo.2011.218. Epub 2011 Nov 15.


Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.

Chang YC, Liu PH, Lee WJ, Chang TJ, Jiang YD, Li HY, Kuo SS, Lee KC, Chuang LM.

Diabetes. 2008 Aug;57(8):2245-52. doi: 10.2337/db08-0377. Epub 2008 May 16.


Polymorphisms in the NPY2R gene show significant associations with BMI that are additive to FTO, MC4R, and NPFFR2 gene effects.

Hunt SC, Hasstedt SJ, Xin Y, Dalley BK, Milash BA, Yakobson E, Gress RE, Davidson LE, Adams TD.

Obesity (Silver Spring). 2011 Nov;19(11):2241-7. doi: 10.1038/oby.2011.239. Epub 2011 Aug 4.


FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women.

Song Y, You NC, Hsu YH, Howard BV, Langer RD, Manson JE, Nathan L, Niu T, F Tinker L, Liu S.

Obesity (Silver Spring). 2008 Nov;16(11):2472-80. doi: 10.1038/oby.2008.408. Epub 2008 Sep 11.


Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR.

PLoS Genet. 2007 Jul;3(7):e115.


A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.

Peters U, North KE, Sethupathy P, Buyske S, Haessler J, Jiao S, Fesinmeyer MD, Jackson RD, Kuller LH, Rajkovic A, Lim U, Cheng I, Schumacher F, Wilkens L, Li R, Monda K, Ehret G, Nguyen KD, Cooper R, Lewis CE, Leppert M, Irvin MR, Gu CC, Houston D, Buzkova P, Ritchie M, Matise TC, Le Marchand L, Hindorff LA, Crawford DC, Haiman CA, Kooperberg C.

PLoS Genet. 2013;9(1):e1003171. doi: 10.1371/journal.pgen.1003171. Epub 2013 Jan 17.


Impact of obesity-related genes in Spanish population.

Martínez-García F, Mansego ML, Rojo-Martínez G, De Marco-Solar G, Morcillo S, Soriguer F, Redón J, Pineda Alonso M, Martín-Escudero JC, Cooper RS, Chaves FJ.

BMC Genet. 2013 Nov 23;14:111. doi: 10.1186/1471-2156-14-111.


Association of morbid obesity with FTO and INSIG2 allelic variants.

Chu X, Erdman R, Susek M, Gerst H, Derr K, Al-Agha M, Wood GC, Hartman C, Yeager S, Blosky MA, Krum W, Stewart WF, Carey D, Benotti P, Still CD, Gerhard GS.

Arch Surg. 2008 Mar;143(3):235-40; discussion 241. doi: 10.1001/archsurg.2007.77.


Genetic susceptibility, birth weight and obesity risk in young Chinese.

Hong J, Shi J, Qi L, Cui B, Gu W, Zhang Y, Li L, Xu M, Wang L, Zhai Y, Miao L, Wang R, Bi Y, Wang W, Ning G.

Int J Obes (Lond). 2013 May;37(5):673-7. doi: 10.1038/ijo.2012.87. Epub 2012 Jun 19.


Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a chinese population.

Cheung CY, Tso AW, Cheung BM, Xu A, Ong KL, Fong CH, Wat NM, Janus ED, Sham PC, Lam KS.

J Clin Endocrinol Metab. 2010 Mar;95(3):1395-403. doi: 10.1210/jc.2009-1465. Epub 2010 Jan 8.


The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China.

Xi B, Shen Y, Zhang M, Liu X, Zhao X, Wu L, Cheng H, Hou D, Lindpaintner K, Liu L, Mi J, Wang X.

BMC Med Genet. 2010 Jul 5;11:107. doi: 10.1186/1471-2350-11-107.

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