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Items: 1 to 20 of 83

1.

Role of herpes simplex virus VP11/12 tyrosine-based motifs in binding and activation of the Src family kinase Lck and recruitment of p85, Grb2, and Shc.

Strunk U, Saffran HA, Wu FW, Smiley JR.

J Virol. 2013 Oct;87(20):11276-86. doi: 10.1128/JVI.01702-13. Epub 2013 Aug 14.

2.

Role of Herpes simplex virus 1 VP11/12 tyrosine-based binding motifs for Src family kinases, p85, Grb2 and Shc in activation of the phosphoinositide 3-kinase-Akt pathway.

Strunk U, Ramos DG, Saffran HA, Smiley JR.

Virology. 2016 Nov;498:31-5. doi: 10.1016/j.virol.2016.08.007. Epub 2016 Aug 17.

PMID:
27543756
3.
4.

Herpes simplex virus requires VP11/12 to activate Src family kinase-phosphoinositide 3-kinase-Akt signaling.

Wagner MJ, Smiley JR.

J Virol. 2011 Mar;85(6):2803-12. doi: 10.1128/JVI.01877-10. Epub 2011 Jan 12.

5.

Herpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activity.

Eaton HE, Saffran HA, Wu FW, Quach K, Smiley JR.

J Virol. 2014 Jul;88(13):7379-88. doi: 10.1128/JVI.00712-14. Epub 2014 Apr 16.

6.

Cell-type-specific tyrosine phosphorylation of the herpes simplex virus tegument protein VP11/12 encoded by gene UL46.

Zahariadis G, Wagner MJ, Doepker RC, Maciejko JM, Crider CM, Jerome KR, Smiley JR.

J Virol. 2008 Jul;82(13):6098-108. doi: 10.1128/JVI.02121-07. Epub 2008 Apr 16.

7.

Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.

Radhakrishnan Y, Maile LA, Ling Y, Graves LM, Clemmons DR.

J Biol Chem. 2008 Jun 13;283(24):16320-31. doi: 10.1074/jbc.M801687200. Epub 2008 Apr 16.

8.

In brain, Axl recruits Grb2 and the p85 regulatory subunit of PI3 kinase; in vitro mutagenesis defines the requisite binding sites for downstream Akt activation.

Weinger JG, Gohari P, Yan Y, Backer JM, Varnum B, Shafit-Zagardo B.

J Neurochem. 2008 Jul;106(1):134-46. doi: 10.1111/j.1471-4159.2008.05343.x. Epub 2008 Jul 1.

9.

Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifs.

Heck E, Friedrich U, Gack MU, Lengenfelder D, Schmidt M, Müller-Fleckenstein I, Fleckenstein B, Ensser A, Biesinger B.

J Virol. 2006 Oct;80(20):9934-42.

10.

Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases.

Poghosyan Z, Robbins SM, Houslay MD, Webster A, Murphy G, Edwards DR.

J Biol Chem. 2002 Feb 15;277(7):4999-5007. Epub 2001 Dec 10.

11.

Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.

VanderKuur J, Allevato G, Billestrup N, Norstedt G, Carter-Su C.

J Biol Chem. 1995 Mar 31;270(13):7587-93.

12.

Lck couples Shc to TCR signaling.

Fukushima A, Hatanaka Y, Chang JW, Takamatsu M, Singh N, Iwashima M.

Cell Signal. 2006 Aug;18(8):1182-9. Epub 2005 Oct 28.

PMID:
16257509
13.

Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.

Higo K, Oda M, Morii H, Takahashi J, Harada Y, Ogawa S, Abe R.

Immunol Invest. 2014;43(3):278-91. doi: 10.3109/08820139.2013.875039. Epub 2014 Jan 29.

PMID:
24475931
14.

T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38.

Fukazawa T, Reedquist KA, Panchamoorthy G, Soltoff S, Trub T, Druker B, Cantley L, Shoelson SE, Band H.

J Biol Chem. 1995 Aug 25;270(34):20177-82.

16.

Involvement of Src-homology-2-domain-containing protein-tyrosine phosphatase 2 in T cell activation.

Tailor P, Jascur T, Williams S, von Willebrand M, Couture C, Mustelin T.

Eur J Biochem. 1996 May 1;237(3):736-42.

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