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Items: 1 to 20 of 75

1.

Carboxyl-terminal modulator protein positively regulates Akt phosphorylation and acts as an oncogenic driver in breast cancer.

Liu YP, Liao WC, Ger LP, Chen JC, Hsu TI, Lee YC, Chang HT, Chen YC, Jan YH, Lee KH, Zeng YH, Hsiao M, Lu PJ.

Cancer Res. 2013 Oct 15;73(20):6194-205. doi: 10.1158/0008-5472.CAN-13-0518. Epub 2013 Aug 13.

2.

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.

Maira SM, Galetic I, Brazil DP, Kaech S, Ingley E, Thelen M, Hemmings BA.

Science. 2001 Oct 12;294(5541):374-80.

3.

Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways.

Ono H, Sakoda H, Fujishiro M, Anai M, Kushiyama A, Fukushima Y, Katagiri H, Ogihara T, Oka Y, Kamata H, Horike N, Uchijima Y, Kurihara H, Asano T.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1576-85. Epub 2007 Jul 5.

4.

New players in high fat diet-induced obesity: LETM1 and CTMP.

Park J, Li Y, Kim SH, Yang KJ, Kong G, Shrestha R, Tran Q, Park KA, Jeon J, Hur GM, Lee CH, Kim DH, Park J.

Metabolism. 2014 Mar;63(3):318-27. doi: 10.1016/j.metabol.2013.10.012. Epub 2013 Oct 31.

PMID:
24333006
5.

Co-delivery of LETM1 and CTMP synergistically inhibits tumor growth in H-ras12V liver cancer model mice.

Shin JY, Chung YS, Kang B, Jiang HL, Yu DY, Han K, Chae C, Moon JH, Jang G, Cho MH.

Cancer Gene Ther. 2013 Mar;20(3):186-94. doi: 10.1038/cgt.2013.6. Epub 2013 Feb 8.

PMID:
23392203
6.

Targeting AKT with the proapoptotic peptide, TAT-CTMP: a novel strategy for the treatment of human pancreatic adenocarcinoma.

Simon PO Jr, McDunn JE, Kashiwagi H, Chang K, Goedegebuure PS, Hotchkiss RS, Hawkins WG.

Int J Cancer. 2009 Aug 15;125(4):942-51. doi: 10.1002/ijc.24424.

7.

Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas.

Knobbe CB, Reifenberger J, Blaschke B, Reifenberger G.

J Natl Cancer Inst. 2004 Mar 17;96(6):483-6.

PMID:
15026474
8.

GRB-7 facilitates HER-2/Neu-mediated signal transduction and tumor formation.

Bai T, Luoh SW.

Carcinogenesis. 2008 Mar;29(3):473-9. Epub 2007 Oct 4.

PMID:
17916906
9.

Activation of Akt independent of PTEN and CTMP tumor-suppressor gene mutations in epilepsy-associated Taylor-type focal cortical dysplasias.

Schick V, Majores M, Engels G, Spitoni S, Koch A, Elger CE, Simon M, Knobbe C, Blümcke I, Becker AJ.

Acta Neuropathol. 2006 Dec;112(6):715-25. Epub 2006 Sep 30.

PMID:
17013611
10.

Phosphatidylethanolamine-binding protein 4 is associated with breast cancer metastasis through Src-mediated Akt tyrosine phosphorylation.

Li H, Huang F, Fan L, Jiang Y, Wang X, Li J, Wang Q, Pan H, Sun J, Cao X, Wang X.

Oncogene. 2014 Sep 11;33(37):4589-98. doi: 10.1038/onc.2013.408. Epub 2013 Nov 25.

PMID:
24276246
11.

Carboxyl-Terminal Modulator Protein Positively Acts as an Oncogenic Driver in Head and Neck Squamous Cell Carcinoma via Regulating Akt phosphorylation.

Chang JW, Jung SN, Kim JH, Shim GA, Park HS, Liu L, Kim JM, Park J, Koo BS.

Sci Rep. 2016 Jun 22;6:28503. doi: 10.1038/srep28503.

12.

Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells.

Hwang SK, Minai-Tehrani A, Yu KN, Chang SH, Kim JE, Lee KH, Park J, Beck GR Jr, Cho MH.

Int J Oncol. 2012 May;40(5):1515-24. doi: 10.3892/ijo.2011.1319. Epub 2011 Dec 23.

PMID:
22200884
13.

Carboxy-Terminal Modulator Protein (CTMP) is a mitochondrial protein that sensitizes cells to apoptosis.

Parcellier A, Tintignac LA, Zhuravleva E, Cron P, Schenk S, Bozulic L, Hemmings BA.

Cell Signal. 2009 Apr;21(4):639-50. doi: 10.1016/j.cellsig.2009.01.016. Epub 2009 Jan 8.

PMID:
19168129
14.

Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein.

Piao L, Li Y, Yang KJ, Park KA, Byun HS, Won M, Hong J, Kim JL, Kweon GR, Hur GM, Seok JH, Cho JY, Chun T, Hess D, Sack R, Maira SM, Brazil DP, Hemmings BA, Park J.

BMC Cell Biol. 2009 Jul 15;10:53. doi: 10.1186/1471-2121-10-53.

15.

Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.

Fathers KE, Bell ES, Rajadurai CV, Cory S, Zhao H, Mourskaia A, Zuo D, Madore J, Monast A, Mes-Masson AM, Grosset AA, Gaboury L, Hallet M, Siegel P, Park M.

Breast Cancer Res. 2012 May 8;14(3):R74.

17.

Lentivirus-mediated carboxyl-terminal modulator protein gene transfection via aerosol in lungs of K-ras null mice.

Hwang SK, Kwon JT, Park SJ, Chang SH, Lee ES, Chung YS, Beck GR Jr, Lee KH, Piao L, Park J, Cho MH.

Gene Ther. 2007 Dec;14(24):1721-30. Epub 2007 Oct 25.

PMID:
17960162
18.
19.

Insulin-like growth factor binding protein-4 and -5 modulate ligand-dependent estrogen receptor-α activation in breast cancer cells in an IGF-independent manner.

Hermani A, Shukla A, Medunjanin S, Werner H, Mayer D.

Cell Signal. 2013 Jun;25(6):1395-402. doi: 10.1016/j.cellsig.2013.02.018. Epub 2013 Mar 14.

PMID:
23499909
20.

The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancer.

Emberley ED, Niu Y, Curtis L, Troup S, Mandal SK, Myers JN, Gibson SB, Murphy LC, Watson PH.

Cancer Res. 2005 Jul 1;65(13):5696-702.

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