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Items: 1 to 20 of 90

1.

Successes and failures for drugs in late-stage development for Alzheimer's disease.

Berk C, Sabbagh MN.

Drugs Aging. 2013 Oct;30(10):783-92. doi: 10.1007/s40266-013-0108-6. Review. Erratum in: Drugs Aging. 2014 Jan;31(1):81.

2.

Why do trials for Alzheimer's disease drugs keep failing? A discontinued drug perspective for 2010-2015.

Mehta D, Jackson R, Paul G, Shi J, Sabbagh M.

Expert Opin Investig Drugs. 2017 Jun;26(6):735-739. doi: 10.1080/13543784.2017.1323868.

PMID:
28460541
3.

Drug development in Alzheimer's disease: the path to 2025.

Cummings J, Aisen PS, DuBois B, Frölich L, Jack CR Jr, Jones RW, Morris JC, Raskin J, Dowsett SA, Scheltens P.

Alzheimers Res Ther. 2016 Sep 20;8:39. doi: 10.1186/s13195-016-0207-9. Review.

4.

Alzheimer's disease: clinical trials and drug development.

Mangialasche F, Solomon A, Winblad B, Mecocci P, Kivipelto M.

Lancet Neurol. 2010 Jul;9(7):702-16. doi: 10.1016/S1474-4422(10)70119-8. Review. Erratum in: Lancet Neurol. 2011 Jun;10(6):501.

PMID:
20610346
5.
6.

New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs.

Salomone S, Caraci F, Leggio GM, Fedotova J, Drago F.

Br J Clin Pharmacol. 2012 Apr;73(4):504-17. doi: 10.1111/j.1365-2125.2011.04134.x. Review.

7.

Drug development status for Alzheimer's disease: present scenario.

Misra S, Medhi B.

Neurol Sci. 2013 Jun;34(6):831-9. doi: 10.1007/s10072-013-1316-x. Epub 2013 Feb 8. Review.

PMID:
23392897
8.

New Drugs from Marine Organisms in Alzheimer's Disease.

Russo P, Kisialiou A, Lamonaca P, Moroni R, Prinzi G, Fini M.

Mar Drugs. 2015 Dec 25;14(1):5. doi: 10.3390/md14010005. Review.

9.

Recent developments in Alzheimer's disease therapeutics.

Rafii MS, Aisen PS.

BMC Med. 2009 Feb 19;7:7. doi: 10.1186/1741-7015-7-7. Review.

10.

Update on Alzheimer's disease therapeutics.

Rafii MS.

Rev Recent Clin Trials. 2013 Jun;8(2):110-8. Review.

PMID:
23859061
11.

New concepts in the drug therapy of Alzheimer's disease.

Hake AM, Farlow MR.

Expert Opin Pharmacother. 2001 Dec;2(12):1975-83. Review.

PMID:
11825329
13.

Drug development for Alzheimer's disease: where are we now and where are we headed?

Sabbagh MN.

Am J Geriatr Pharmacother. 2009 Jun;7(3):167-85. doi: 10.1016/j.amjopharm.2009.06.003. Review.

14.

Alzheimer's disease drug development in 2008 and beyond: problems and opportunities.

Becker RE, Greig NH.

Curr Alzheimer Res. 2008 Aug;5(4):346-57. Review.

15.

Drug repositioning for Alzheimer's disease.

Corbett A, Pickett J, Burns A, Corcoran J, Dunnett SB, Edison P, Hagan JJ, Holmes C, Jones E, Katona C, Kearns I, Kehoe P, Mudher A, Passmore A, Shepherd N, Walsh F, Ballard C.

Nat Rev Drug Discov. 2012 Nov;11(11):833-46. doi: 10.1038/nrd3869. Review.

PMID:
23123941
16.

Discovering new treatments for Alzheimer's disease by repurposing approved medications.

Appleby BS, Cummings JL.

Curr Top Med Chem. 2013;13(18):2306-27. Review.

PMID:
24059463
17.

Prevention studies in Alzheimer's disease: progress towards the development of new therapeutics.

Coley N, Gallini A, Andrieu S.

CNS Drugs. 2015 Jul;29(7):519-28. doi: 10.1007/s40263-015-0256-9.

PMID:
26188654
18.

Translational medicine lessons from flurizan's failure in Alzheimer's disease (AD) trial: Implication for future drug discovery and development for AD.

Wan HI, Jacobsen JS, Rutkowski JL, Feuerstein GZ.

Clin Transl Sci. 2009 Jun;2(3):242-7. doi: 10.1111/j.1752-8062.2009.00121.x. No abstract available.

19.

Alzheimer's disease: current and future therapeutic perspectives.

Gauthier S.

Prog Neuropsychopharmacol Biol Psychiatry. 2001 Jan;25(1):73-89. Review.

PMID:
11263760
20.

Global Trends in Alzheimer Disease Clinical Development: Increasing the Probability of Success.

Sugino H, Watanabe A, Amada N, Yamamoto M, Ohgi Y, Kostic D, Sanchez R.

Clin Ther. 2015 Aug;37(8):1632-42. doi: 10.1016/j.clinthera.2015.07.006. Epub 2015 Aug 1.

PMID:
26243073

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