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Items: 1 to 20 of 101

1.

Parental history of type 2 diabetes, TCF7L2 variant and lower insulin secretion are associated with incident hypertension. Data from the DESIR and RISC cohorts.

Bonnet F, Roussel R, Natali A, Cauchi S, Petrie J, Laville M, Yengo L, Froguel P, Lange C, Lantieri O, Marre M, Balkau B, Ferrannini E; DESIR and RISC Study Groups.

Diabetologia. 2013 Nov;56(11):2414-23. doi: 10.1007/s00125-013-3021-y. Epub 2013 Aug 14.

2.

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

Schäfer SA, Tschritter O, Machicao F, Thamer C, Stefan N, Gallwitz B, Holst JJ, Dekker JM, 't Hart LM, Nijpels G, van Haeften TW, Häring HU, Fritsche A.

Diabetologia. 2007 Dec;50(12):2443-50. Epub 2007 Jul 28. Erratum in: Diabetologia. 2009 Mar;52(3):557. Dosage error in article text. Diabetologia. 2008 Jan;51(1):208. t' Hart, L M [corrected to 't Hart, L M].

3.

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion.

Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M.

Diabetologia. 2007 Jun;50(6):1192-200. Epub 2007 Apr 17.

PMID:
17437080
4.

Risk factors for incident type 2 diabetes in individuals with a BMI of <27 kg/m2: the role of gamma-glutamyltransferase. Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR).

Gautier A, Balkau B, Lange C, Tichet J, Bonnet F; DESIR Study Group.

Diabetologia. 2010 Feb;53(2):247-53. doi: 10.1007/s00125-009-1602-6. Epub 2009 Nov 20.

PMID:
19936701
5.

Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes.

Hindy G, Sonestedt E, Ericson U, Jing XJ, Zhou Y, Hansson O, Renström E, Wirfält E, Orho-Melander M.

Diabetologia. 2012 Oct;55(10):2646-2654. doi: 10.1007/s00125-012-2634-x. Epub 2012 Jul 11.

6.

Glucose tolerance and free fatty acid metabolism in adults with variations in TCF7L2 rs7903146.

Lu J, Varghese RT, Zhou L, Vella A, Jensen MD.

Metabolism. 2017 Mar;68:55-63. doi: 10.1016/j.metabol.2016.11.018. Epub 2016 Dec 9.

PMID:
28183453
7.

Pleiotropic effects of TCF7L2 gene variants and its modulation in the metabolic syndrome: from the LIPGENE study.

Delgado-Lista J, Perez-Martinez P, García-Rios A, Phillips CM, Williams CM, Gulseth HL, Helal O, Blaak EE, Kiec-Wilk B, Basu S, Drevon CA, Defoort C, Saris WH, Wybranska I, Riserus U, Lovegrove JA, Roche HM, Lopez-Miranda J.

Atherosclerosis. 2011 Jan;214(1):110-6. doi: 10.1016/j.atherosclerosis.2010.10.027. Epub 2010 Nov 3.

PMID:
21115178
8.

Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion.

Heni M, Ketterer C, Thamer C, Herzberg-Schäfer SA, Guthoff M, Stefan N, Machicao F, Staiger H, Fritsche A, Häring HU.

Diabetes. 2010 Dec;59(12):3247-52. doi: 10.2337/db10-0674. Epub 2010 Aug 29.

9.

TCF7L2 genetic variants and progression to diabetes in the Chinese population: pleiotropic effects on insulin secretion and insulin resistance.

Chang YC, Chiu YF, Ho LL, Ting CT, Shih KC, Curb JD, Chen YD, Li HY, Chuang LM.

J Mol Med (Berl). 2010 Feb;88(2):183-92. doi: 10.1007/s00109-009-0542-4. Epub 2009 Oct 6.

PMID:
19806338
10.

Association of TCF7L2 SNPs with age at onset of type 2 diabetes and proinsulin/insulin ratio but not with glucagon-like peptide 1.

Silbernagel G, Renner W, Grammer TB, Hügl SR, Bertram J, Kleber ME, Hoffmann MM, Winkelmann BR, März W, Boehm BO.

Diabetes Metab Res Rev. 2011 Jul;27(5):499-505. doi: 10.1002/dmrr.1194.

PMID:
21384500
11.

TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study.

Cauchi S, Meyre D, Choquet H, Dina C, Born C, Marre M, Balkau B, Froguel P; DESIR Study Group.

Diabetes. 2006 Nov;55(11):3189-92. Erratum in: Diabetes. 2006 Dec;55(12):3635.

12.

Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele.

Færch K, Pilgaard K, Knop FK, Hansen T, Pedersen O, Jørgensen T, Holst JJ.

Diabetes Obes Metab. 2013 Jan;15(1):91-5. doi: 10.1111/j.1463-1326.2012.01675.x. Epub 2012 Sep 9.

PMID:
22862926
13.

Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population.

González-Sánchez JL, Martínez-Larrad MT, Zabena C, Pérez-Barba M, Serrano-Ríos M.

Diabetologia. 2008 Nov;51(11):1993-7. doi: 10.1007/s00125-008-1129-2. Epub 2008 Aug 19.

PMID:
18712344
14.

Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men.

Dahlgren A, Zethelius B, Jensevik K, Syvänen AC, Berne C; ULSAM Cohort.

Diabetologia. 2007 Sep;50(9):1852-7. Epub 2007 Jul 6.

PMID:
17618413
15.

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.

Kirchhoff K, Machicao F, Haupt A, Schäfer SA, Tschritter O, Staiger H, Stefan N, Häring HU, Fritsche A.

Diabetologia. 2008 Apr;51(4):597-601. doi: 10.1007/s00125-008-0926-y. Epub 2008 Feb 9.

PMID:
18264689
16.

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

Pilgaard K, Jensen CB, Schou JH, Lyssenko V, Wegner L, Brøns C, Vilsbøll T, Hansen T, Madsbad S, Holst JJ, Vølund A, Poulsen P, Groop L, Pedersen O, Vaag AA.

Diabetologia. 2009 Jul;52(7):1298-307. doi: 10.1007/s00125-009-1307-x. Epub 2009 Mar 14.

PMID:
19288077
17.

TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals.

Le Bacquer O, Kerr-Conte J, Gargani S, Delalleau N, Huyvaert M, Gmyr V, Froguel P, Neve B, Pattou F.

Diabetologia. 2012 Oct;55(10):2677-2681. doi: 10.1007/s00125-012-2660-8. Epub 2012 Aug 22.

PMID:
22911383
18.

Association of TCF7L2 and GCG Gene Variants with Insulin Secretion, Insulin Resistance, and Obesity in New-onset Diabetes.

Zhang L, Zhang M, Wang JJ, Wang CJ, Ren YC, Wang BY, Zhang HY, Yang XY, Zhao Y, Han CY, Zhou JM, Pang C, Yin L, Zhao JZ, Luo XP, Hu DS.

Biomed Environ Sci. 2016 Nov;29(11):814-817. doi: 10.3967/bes2016.108.

19.

TCF7L2 polymorphism, weight loss and proinsulin:insulin ratio in the diabetes prevention program.

McCaffery JM, Jablonski KA, Franks PW, Dagogo-Jack S, Wing RR, Knowler WC, Delahanty L, Dabelea D, Hamman R, Shuldiner AR, Florez JC; Diabetes Prevention Program Research Group.

PLoS One. 2011;6(7):e21518. doi: 10.1371/journal.pone.0021518. Epub 2011 Jul 26.

20.

Variants and haplotypes of TCF7L2 are associated with β-cell function in patients with newly diagnosed type 2 diabetes: the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 1.

Bonetti S, Trombetta M, Malerba G, Boselli L, Trabetti E, Muggeo M, Stoico V, Negri C, Pignatti PF, Bonora E, Bonadonna RC.

J Clin Endocrinol Metab. 2011 Feb;96(2):E389-93. doi: 10.1210/jc.2010-1677. Epub 2010 Dec 15.

PMID:
21159844

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