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Items: 1 to 20 of 170

1.

Nm23-h1 binds to gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis.

Marino N, Marshall JC, Collins JW, Zhou M, Qian Y, Veenstra T, Steeg PS.

Cancer Res. 2013 Oct 1;73(19):5949-62. doi: 10.1158/0008-5472.CAN-13-0368. Epub 2013 Aug 12.

2.

Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer.

Marshall JC, Collins JW, Nakayama J, Horak CE, Liewehr DJ, Steinberg SM, Albaugh M, Vidal-Vanaclocha F, Palmieri D, Barbier M, Murone M, Steeg PS.

J Natl Cancer Inst. 2012 Sep 5;104(17):1306-19. doi: 10.1093/jnci/djs319. Epub 2012 Aug 21.

3.

Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer.

Palmieri D, Halverson DO, Ouatas T, Horak CE, Salerno M, Johnson J, Figg WD, Hollingshead M, Hursting S, Berrigan D, Steinberg SM, Merino MJ, Steeg PS.

J Natl Cancer Inst. 2005 May 4;97(9):632-42.

PMID:
15870434
4.

Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity.

Zhang Q, McCorkle JR, Novak M, Yang M, Kaetzel DM.

Int J Cancer. 2011 Jan 1;128(1):40-50. doi: 10.1002/ijc.25307.

5.

Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.

Boissan M, De Wever O, Lizarraga F, Wendum D, Poincloux R, Chignard N, Desbois-Mouthon C, Dufour S, Nawrocki-Raby B, Birembaut P, Bracke M, Chavrier P, Gespach C, Lacombe ML.

Cancer Res. 2010 Oct 1;70(19):7710-22. doi: 10.1158/0008-5472.CAN-10-1887. Epub 2010 Sep 14.

6.

Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2.

Horak CE, Mendoza A, Vega-Valle E, Albaugh M, Graff-Cherry C, McDermott WG, Hua E, Merino MJ, Steinberg SM, Khanna C, Steeg PS.

Cancer Res. 2007 Dec 15;67(24):11751-9.

7.

Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.

Horak CE, Lee JH, Elkahloun AG, Boissan M, Dumont S, Maga TK, Arnaud-Dabernat S, Palmieri D, Stetler-Stevenson WG, Lacombe ML, Meltzer PS, Steeg PS.

Cancer Res. 2007 Aug 1;67(15):7238-46.

8.

Nm23-H1 suppresses hepatocarcinoma cell adhesion and migration on fibronectin by modulating glycosylation of integrin beta1.

She S, Xu B, He M, Lan X, Wang Q.

J Exp Clin Cancer Res. 2010 Jul 11;29:93. doi: 10.1186/1756-9966-29-93.

9.

[Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1].

Che GW, Zhou QH, Zhu W, Wang YP, Qin Y, Liu LX, Chen XH, Sun YL, Sun ZF.

Ai Zheng. 2005 Mar;24(3):278-84. Chinese.

PMID:
15757527
10.

H-prune-nm23-H1 protein complex and correlation to pathways in cancer metastasis.

Garzia L, Roma C, Tata N, Pagnozzi D, Pucci P, Zollo M.

J Bioenerg Biomembr. 2006 Aug;38(3-4):205-13.

PMID:
17103319
12.

Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing.

Ma W, Chen J, Xue X, Wang Z, Liu H, Wang T, Bai Y, Tang SC, Zhou Q.

Biochem Biophys Res Commun. 2008 Jul 4;371(3):425-30. doi: 10.1016/j.bbrc.2008.04.083. Epub 2008 Apr 25.

PMID:
18440302
13.

nm23-H1 is a negative regulator of TGF-╬▓1-dependent induction of epithelial-mesenchymal transition.

Zhao R, Gong L, Li L, Guo L, Zhu D, Wu Z, Zhou Q.

Exp Cell Res. 2013 Mar 10;319(5):740-9. doi: 10.1016/j.yexcr.2012.10.013. Epub 2012 Nov 5.

PMID:
23137649
14.
15.

[Lentivirus-mediated stable silencing of nm23-H1 gene in lung cancer cells and the influence on biological behavior].

Luo M, Zhu D, Gong L, Qiu X, Zu L, Sun L, Wu Z, Zhou Q.

Zhongguo Fei Ai Za Zhi. 2012 Mar;15(3):139-45. doi: 10.3779/j.issn.1009-3419.2012.03.02. Chinese.

16.

ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton.

Yuan X, Yu L, Li J, Xie G, Rong T, Zhang L, Chen J, Meng Q, Irving AT, Wang D, Williams ED, Liu JP, Sadler AJ, Williams BR, Shen L, Xu D.

Cancer Res. 2013 Jun 15;73(12):3625-37. doi: 10.1158/0008-5472.CAN-12-3879. Epub 2013 Mar 27. Erratum in: Cancer Res. 2016 Aug 1;76(15):4592.

18.

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction.

Carotenuto M, Pedone E, Diana D, de Antonellis P, D┼żeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M.

Sci Rep. 2013;3:1351. doi: 10.1038/srep01351.

19.

Nm23-H1 homologs suppress tumor cell motility and anchorage independent growth.

McDermott WG, Boissan M, Lacombe ML, Steeg PS, Horak CE.

Clin Exp Metastasis. 2008;25(2):131-8. Epub 2007 Dec 5.

PMID:
18058029
20.

A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.

Carotenuto M, de Antonellis P, Chiarolla CM, Attanasio C, Damiani V, Boffa I, Aiese N, Pedone E, Accordi B, Basso G, Navas L, Imbimbo C, Zollo M.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Feb;388(2):257-69. doi: 10.1007/s00210-014-1035-8. Epub 2014 Aug 20.

PMID:
25138575

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