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Items: 1 to 20 of 80

1.

Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides.

Uchtenhagen H, Abualrous ET, Stahl E, Allerbring EB, Sluijter M, Zacharias M, Sandalova T, van Hall T, Springer S, Nygren PÅ, Achour A.

Eur J Immunol. 2013 Nov;43(11):3051-60. doi: 10.1002/eji.201343456. Epub 2013 Aug 30.

2.

Going Pro to enhance T-cell immunogenicity: easy as π?

Hickman HD, Yewdell JW.

Eur J Immunol. 2013 Nov;43(11):2814-7. doi: 10.1002/eji.201344095. Epub 2013 Oct 24.

4.

Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.

van Stipdonk MJ, Badia-Martinez D, Sluijter M, Offringa R, van Hall T, Achour A.

Cancer Res. 2009 Oct 1;69(19):7784-92. doi: 10.1158/0008-5472.CAN-09-1724. Epub 2009 Sep 29.

6.

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations.

Turner SJ, Kedzierska K, Komodromou H, La Gruta NL, Dunstone MA, Webb AI, Webby R, Walden H, Xie W, McCluskey J, Purcell AW, Rossjohn J, Doherty PC.

Nat Immunol. 2005 Apr;6(4):382-9. Epub 2005 Feb 27.

PMID:
15735650
7.

Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance.

Meijers R, Lai CC, Yang Y, Liu JH, Zhong W, Wang JH, Reinherz EL.

J Mol Biol. 2005 Feb 4;345(5):1099-110. Epub 2004 Dec 8.

PMID:
15644207
8.

Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.

Velloso LM, Michaëlsson J, Ljunggren HG, Schneider G, Achour A.

J Immunol. 2004 May 1;172(9):5504-11.

9.
10.

A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.

Bianchi V, Bulek A, Fuller A, Lloyd A, Attaf M, Rizkallah PJ, Dolton G, Sewell AK, Cole DK.

J Biol Chem. 2016 Apr 22;291(17):8951-9. doi: 10.1074/jbc.M115.707414. Epub 2016 Feb 25.

11.

The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer.

Hafstrand I, Doorduijn EM, Duru AD, Buratto J, Oliveira CC, Sandalova T, van Hall T, Achour A.

J Immunol. 2016 Mar 1;196(5):2327-34. doi: 10.4049/jimmunol.1502249. Epub 2016 Jan 22.

12.

Proteasomal cleavage does not determine immunogenicity of gp100-derived peptides gp100 209-217 and gp100 209-217T210M.

Nagorsen D, Servis C, Lévy N, Provenzano M, Dudley ME, Marincola FM, Lévy F.

Cancer Immunol Immunother. 2004 Sep;53(9):817-24. Epub 2004 May 5.

PMID:
15133631
13.

TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.

Miles JJ, Borg NA, Brennan RM, Tynan FE, Kjer-Nielsen L, Silins SL, Bell MJ, Burrows JM, McCluskey J, Rossjohn J, Burrows SR.

J Immunol. 2006 Nov 15;177(10):6804-14.

14.

Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics.

Allerbring EB, Duru AD, Uchtenhagen H, Madhurantakam C, Tomek MB, Grimm S, Mazumdar PA, Friemann R, Uhlin M, Sandalova T, Nygren PÅ, Achour A.

Eur J Immunol. 2012 Nov;42(11):2990-3000. doi: 10.1002/eji.201242588. Epub 2012 Sep 20.

15.
16.

High affinity xenoreactive TCR:MHC interaction recruits CD8 in absence of binding to MHC.

Buslepp J, Kerry SE, Loftus D, Frelinger JA, Appella E, Collins EJ.

J Immunol. 2003 Jan 1;170(1):373-83.

17.

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

Tynan FE, Burrows SR, Buckle AM, Clements CS, Borg NA, Miles JJ, Beddoe T, Whisstock JC, Wilce MC, Silins SL, Burrows JM, Kjer-Nielsen L, Kostenko L, Purcell AW, McCluskey J, Rossjohn J.

Nat Immunol. 2005 Nov;6(11):1114-22. Epub 2005 Sep 25.

PMID:
16186824
18.

Peptide recognition by two HLA-A2/Tax11-19-specific T cell clones in relationship to their MHC/peptide/TCR crystal structures.

Hausmann S, Biddison WE, Smith KJ, Ding YH, Garboczi DN, Utz U, Wiley DC, Wucherpfennig KW.

J Immunol. 1999 May 1;162(9):5389-97.

19.

CTL recognition of a bulged viral peptide involves biased TCR selection.

Miles JJ, Elhassen D, Borg NA, Silins SL, Tynan FE, Burrows JM, Purcell AW, Kjer-Nielsen L, Rossjohn J, Burrows SR, McCluskey J.

J Immunol. 2005 Sep 15;175(6):3826-34.

20.

Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes.

Schaft N, Willemsen RA, de Vries J, Lankiewicz B, Essers BW, Gratama JW, Figdor CG, Bolhuis RL, Debets R, Adema GJ.

J Immunol. 2003 Feb 15;170(4):2186-94.

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