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PCNA promotes processive DNA end resection by Exo1.

Chen X, Paudyal SC, Chin RI, You Z.

Nucleic Acids Res. 2013 Nov;41(20):9325-38. doi: 10.1093/nar/gkt672. Epub 2013 Aug 11.


14-3-3 proteins restrain the Exo1 nuclease to prevent overresection.

Chen X, Kim IK, Honaker Y, Paudyal SC, Koh WK, Sparks M, Li S, Piwnica-Worms H, Ellenberger T, You Z.

J Biol Chem. 2015 May 8;290(19):12300-12. doi: 10.1074/jbc.M115.644005. Epub 2015 Apr 1.


Poly(ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities.

Cheruiyot A, Paudyal SC, Kim IK, Sparks M, Ellenberger T, Piwnica-Worms H, You Z.

DNA Repair (Amst). 2015 Nov;35:106-15. doi: 10.1016/j.dnarep.2015.09.021. Epub 2015 Sep 30.


DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair.

Tomimatsu N, Mukherjee B, Harris JL, Boffo FL, Hardebeck MC, Potts PR, Khanna KK, Burma S.

J Biol Chem. 2017 Jun 30;292(26):10779-10790. doi: 10.1074/jbc.M116.772475. Epub 2017 May 17.


Exo1 and Mre11 execute meiotic DSB end resection in the protist Tetrahymena.

Lukaszewicz A, Shodhan A, Loidl J.

DNA Repair (Amst). 2015 Nov;35:137-43. doi: 10.1016/j.dnarep.2015.08.005. Epub 2015 Sep 26.


Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.

Bolderson E, Tomimatsu N, Richard DJ, Boucher D, Kumar R, Pandita TK, Burma S, Khanna KK.

Nucleic Acids Res. 2010 Apr;38(6):1821-31. doi: 10.1093/nar/gkp1164. Epub 2009 Dec 17.


Mechanistic analysis of Xenopus EXO1's function in 5'-strand resection at DNA double-strand breaks.

Liao S, Toczylowski T, Yan H.

Nucleic Acids Res. 2011 Aug;39(14):5967-77. doi: 10.1093/nar/gkr216. Epub 2011 Apr 13.


Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection.

Cannavo E, Cejka P, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):E1661-8. doi: 10.1073/pnas.1305166110. Epub 2013 Apr 15.


Analysis of MRE11's function in the 5'-->3' processing of DNA double-strand breaks.

Liao S, Guay C, Toczylowski T, Yan H.

Nucleic Acids Res. 2012 May;40(10):4496-506. doi: 10.1093/nar/gks044. Epub 2012 Feb 8.


Sumoylation regulates EXO1 stability and processing of DNA damage.

Bologna S, Altmannova V, Valtorta E, Koenig C, Liberali P, Gentili C, Anrather D, Ammerer G, Pelkmans L, Krejci L, Ferrari S.

Cell Cycle. 2015 Aug 3;14(15):2439-50. doi: 10.1080/15384101.2015.1060381. Epub 2015 Jun 17.


Single-molecule imaging reveals the mechanism of Exo1 regulation by single-stranded DNA binding proteins.

Myler LR, Gallardo IF, Zhou Y, Gong F, Yang SH, Wold MS, Miller KM, Paull TT, Finkelstein IJ.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1170-9. doi: 10.1073/pnas.1516674113. Epub 2016 Feb 16.


Exonuclease 1-dependent and independent mismatch repair.

Goellner EM, Putnam CD, Kolodner RD.

DNA Repair (Amst). 2015 Aug;32:24-32. doi: 10.1016/j.dnarep.2015.04.010. Epub 2015 Apr 30. Review.


BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair.

Nimonkar AV, Genschel J, Kinoshita E, Polaczek P, Campbell JL, Wyman C, Modrich P, Kowalczykowski SC.

Genes Dev. 2011 Feb 15;25(4):350-62. doi: 10.1101/gad.2003811.


DNA end resection--unraveling the tail.

Mimitou EP, Symington LS.

DNA Repair (Amst). 2011 Mar 7;10(3):344-8. doi: 10.1016/j.dnarep.2010.12.004. Epub 2011 Jan 11. Review.


The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks.

Ngo GH, Lydall D.

Nucleic Acids Res. 2015 May 26;43(10):5017-32. doi: 10.1093/nar/gkv409. Epub 2015 Apr 29.


The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1.

Yang SH, Zhou R, Campbell J, Chen J, Ha T, Paull TT.

EMBO J. 2013 Jan 9;32(1):126-39. doi: 10.1038/emboj.2012.314. Epub 2012 Nov 23.


DNA end resection by CtIP and exonuclease 1 prevents genomic instability.

Eid W, Steger M, El-Shemerly M, Ferretti LP, Peña-Diaz J, König C, Valtorta E, Sartori AA, Ferrari S.

EMBO Rep. 2010 Dec;11(12):962-8. doi: 10.1038/embor.2010.157. Epub 2010 Nov 5.


PHF11 promotes DSB resection, ATR signaling, and HR.

Gong Y, Handa N, Kowalczykowski SC, de Lange T.

Genes Dev. 2017 Jan 1;31(1):46-58. doi: 10.1101/gad.291807.116. Epub 2017 Jan 23.

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