Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 119

1.

Synthesis, enzyme kinetics and computational evaluation of N-(β-D-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors.

Polyák M, Varga G, Szilágyi B, Juhász L, Docsa T, Gergely P, Begum J, Hayes JM, Somsák L.

Bioorg Med Chem. 2013 Sep 15;21(18):5738-47. doi: 10.1016/j.bmc.2013.07.024. Epub 2013 Jul 25.

PMID:
23938052
2.

Synthesis of heterocyclic N-(β-D-glucopyranosyl)carboxamides for inhibition of glycogen phosphorylase.

Kónya B, Docsa T, Gergely P, Somsák L.

Carbohydr Res. 2012 Apr 1;351:56-63. doi: 10.1016/j.carres.2012.01.020. Epub 2012 Jan 31.

PMID:
22365837
3.

Synthesis of 2-(β-D-glucopyranosylamino)-5-substituted-1,3,4-oxadiazoles for inhibition of glycogen phosphorylase.

Tóth M, Szőcs B, Kaszás T, Docsa T, Gergely P, Somsák L.

Carbohydr Res. 2013 Nov 15;381:196-204. doi: 10.1016/j.carres.2013.04.025. Epub 2013 Apr 27.

PMID:
23673237
4.

Synthesis of variously coupled conjugates of D-glucose, 1,3,4-oxadiazole, and 1,2,3-triazole for inhibition of glycogen phosphorylase.

Kun S, Nagy GZ, Tóth M, Czecze L, Van Nhien AN, Docsa T, Gergely P, Charavgi MD, Skourti PV, Chrysina ED, Patonay T, Somsák L.

Carbohydr Res. 2011 Sep 6;346(12):1427-38. doi: 10.1016/j.carres.2011.03.004. Epub 2011 Mar 8.

PMID:
21470596
5.

New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazoles, nanomolar inhibitors of glycogen phosphorylase.

Kun S, Bokor É, Varga G, Szőcs B, Páhi A, Czifrák K, Tóth M, Juhász L, Docsa T, Gergely P, Somsák L.

Eur J Med Chem. 2014 Apr 9;76:567-79. doi: 10.1016/j.ejmech.2014.02.041. Epub 2014 Feb 15.

PMID:
24608000
6.

Synthesis of 2-(β-D-glucopyranosyl)-5-(substituted-amino)-1,3,4-oxa- and -thiadiazoles for the inhibition of glycogen phosphorylase.

Szőcs B, Tóth M, Docsa T, Gergely P, Somsák L.

Carbohydr Res. 2013 Nov 15;381:187-95. doi: 10.1016/j.carres.2013.03.009. Epub 2013 Mar 21.

PMID:
23582340
7.

C-Glucopyranosyl-1,2,4-triazol-5-ones: synthesis and inhibition of glycogen phosphorylase.

Bokor É, Széles Z, Docsa T, Gergely P, Somsák L.

Carbohydr Res. 2016 Jun 24;429:128-34. doi: 10.1016/j.carres.2015.12.005. Epub 2015 Dec 24.

PMID:
26818133
8.

Synthesis of N-(beta-D-glucopyranosyl) monoamides of dicarboxylic acids as potential inhibitors of glycogen phosphorylase.

Czifrák K, Hadady Z, Docsa T, Gergely P, Schmidt J, Wessjohann L, Somsák L.

Carbohydr Res. 2006 Jun 12;341(8):947-56. Epub 2006 Mar 29.

PMID:
16564511
9.

Synthesis of new glycosyl biuret and urea derivatives as potential glycoenzyme inhibitors.

Felföldi N, Tóth M, Chrysina ED, Charavgi MD, Alexacou KM, Somsák L.

Carbohydr Res. 2010 Jan 26;345(2):208-13. doi: 10.1016/j.carres.2009.10.016. Epub 2009 Nov 10.

PMID:
20004366
10.

Synthesis of N-(beta-D-glucopyranosyl)- and N-(2-acetamido-2-deoxy-beta-D-glucopyranosyl) amides as inhibitors of glycogen phosphorylase.

Györgydeák Z, Hadady Z, Felföldi N, Krakomperger A, Nagy V, Tóth M, Brunyánszki A, Docsa T, Gergely P, Somsák L.

Bioorg Med Chem. 2004 Sep 15;12(18):4861-70.

PMID:
15336265
11.

C-(2-Deoxy-d-arabino-hex-1-enopyranosyl)-oxadiazoles: synthesis of possible isomers and their evaluation as glycogen phosphorylase inhibitors.

Bokor É, Szennyes E, Csupász T, Tóth N, Docsa T, Gergely P, Somsák L.

Carbohydr Res. 2015 Aug 14;412:71-9. doi: 10.1016/j.carres.2015.04.016. Epub 2015 May 2.

PMID:
26082971
12.

Synthesis of substituted 2-(β-D-glucopyranosyl)-benzimidazoles and their evaluation as inhibitors of glycogen phosphorylase.

Bokor É, Szilágyi E, Docsa T, Gergely P, Somsák L.

Carbohydr Res. 2013 Nov 15;381:179-86. doi: 10.1016/j.carres.2013.01.011. Epub 2013 Jan 29.

PMID:
23419607
13.

Synthesis and structure-activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase.

Tóth M, Kun S, Bokor E, Benltifa M, Tallec G, Vidal S, Docsa T, Gergely P, Somsák L, Praly JP.

Bioorg Med Chem. 2009 Jul 1;17(13):4773-85. doi: 10.1016/j.bmc.2009.04.036. Epub 2009 Apr 23.

PMID:
19450985
14.

Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.

Kantsadi AL, Bokor É, Kun S, Stravodimos GA, Chatzileontiadou DS, Leonidas DD, Juhász-Tóth É, Szakács A, Batta G, Docsa T, Gergely P, Somsák L.

Eur J Med Chem. 2016 Nov 10;123:737-45. doi: 10.1016/j.ejmech.2016.06.049. Epub 2016 Jul 12.

PMID:
27522507
15.

N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.

Nagy V, Felföldi N, Kónya B, Praly JP, Docsa T, Gergely P, Chrysina ED, Tiraidis C, Kosmopoulou MN, Alexacou KM, Konstantakaki M, Leonidas DD, Zographos SE, Oikonomakos NG, Kozmon S, Tvaroška I, Somsák L.

Bioorg Med Chem. 2012 Mar 1;20(5):1801-16. doi: 10.1016/j.bmc.2011.12.059. Epub 2012 Jan 20.

PMID:
22325154
16.

Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methods.

Czifrák K, Páhi A, Deák S, Kiss-Szikszai A, Kövér KE, Docsa T, Gergely P, Alexacou KM, Papakonstantinou M, Leonidas DD, Zographos SE, Chrysina ED, Somsák L.

Bioorg Med Chem. 2014 Aug 1;22(15):4028-41. doi: 10.1016/j.bmc.2014.05.076. Epub 2014 Jun 16.

PMID:
25009003
17.
18.

Synthesis and glycogen phosphorylase inhibitory activity of N-(beta-D-glucopyranosyl)amides possessing 1,4-benzodioxane moiety.

Czakó Z, Juhász L, Kenéz A, Czifrák K, Somsák L, Docsa T, Gergely P, Antus S.

Bioorg Med Chem. 2009 Sep 15;17(18):6738-41. doi: 10.1016/j.bmc.2009.07.052. Epub 2009 Jul 25.

PMID:
19703777
20.

Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments.

Somsák L, Nagya V, Hadady Z, Docsa T, Gergely P.

Curr Pharm Des. 2003;9(15):1177-89. Review.

PMID:
12769745

Supplemental Content

Support Center