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Items: 1 to 20 of 91

1.
2.

Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors.

Makhaeva GF, Boltneva NP, Lushchekina SV, Serebryakova OG, Stupina TS, Terentiev AA, Serkov IV, Proshin AN, Bachurin SO, Richardson RJ.

Bioorg Med Chem. 2016 Mar 1;24(5):1050-62. doi: 10.1016/j.bmc.2016.01.031. Epub 2016 Jan 18.

PMID:
26827140
3.

Pyridine sulfonamide as a small key organic molecule for the potential treatment of type-II diabetes mellitus and Alzheimer's disease: In vitro studies against yeast α-glucosidase, acetylcholinesterase and butyrylcholinesterase.

Riaz S, Khan IU, Bajda M, Ashraf M, Qurat-Ul-Ain, Shaukat A, Rehman TU, Mutahir S, Hussain S, Mustafa G, Yar M.

Bioorg Chem. 2015 Dec;63:64-71. doi: 10.1016/j.bioorg.2015.09.008. Epub 2015 Sep 30.

PMID:
26451651
5.

The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain.

Chen VP, Xie HQ, Chan WK, Leung KW, Chan GK, Choi RC, Bon S, Massoulié J, Tsim KW.

J Biol Chem. 2010 Aug 27;285(35):27265-78. doi: 10.1074/jbc.M110.113647. Epub 2010 Jun 21.

6.

Kinetics and molecular docking studies of loganin, morroniside and 7-O-galloyl-D-sedoheptulose derived from Corni fructus as cholinesterase and β-secretase 1 inhibitors.

Bhakta HK, Park CH, Yokozawa T, Min BS, Jung HA, Choi JS.

Arch Pharm Res. 2016 Jun;39(6):794-805. doi: 10.1007/s12272-016-0745-5. Epub 2016 Apr 22.

PMID:
27106028
7.

Evolution of acetylcholinesterase and butyrylcholinesterase in the vertebrates: an atypical butyrylcholinesterase from the Medaka Oryzias latipes.

Pezzementi L, Nachon F, Chatonnet A.

PLoS One. 2011 Feb 25;6(2):e17396. doi: 10.1371/journal.pone.0017396. Erratum in: PLoS One. 2011;6(3). doi: 10.1371/annotation/938a4e59-a5d1-448c-b7c1-632bf9e7e8ef.

8.

Blood acetylcholinesterase and butyrylcholinesterase as biomarkers of cholinesterase depression among pesticide handlers.

Strelitz J, Engel LS, Keifer MC.

Occup Environ Med. 2014 Dec;71(12):842-7. doi: 10.1136/oemed-2014-102315. Epub 2014 Sep 4.

9.

Amino acid residues involved in the interaction of acetylcholinesterase and butyrylcholinesterase with the carbamates Ro 02-0683 and bambuterol, and with terbutaline.

Kovarik Z, Radić Z, Grgas B, Skrinjarić-Spoljar M, Reiner E, Simeon-Rudolf V.

Biochim Biophys Acta. 1999 Aug 17;1433(1-2):261-71.

PMID:
10446376
10.

Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases.

Saxena A, Fedorko JM, Vinayaka CR, Medhekar R, Radić Z, Taylor P, Lockridge O, Doctor BP.

Eur J Biochem. 2003 Nov;270(22):4447-58.

11.

Potent AChE and BChE inhibitors isolated from seeds of Peganum harmala Linn by a bioassay-guided fractionation.

Yang Y, Cheng X, Liu W, Chou G, Wang Z, Wang C.

J Ethnopharmacol. 2015 Jun 20;168:279-86. doi: 10.1016/j.jep.2015.03.070. Epub 2015 Apr 8.

PMID:
25862961
12.

Design and Synthesis of New Dual Binding Site Cholinesterase Inhibitors: in vitro Inhibition Studies with in silico Docking.

Yar M, Bajda M, Mehmood RA, Sidra LR, Ullah N, Shahzadi L, Ashraf M, Ismail T, Shahzad SA, Khan ZA, Naqvi SA, Mahmood N.

Lett Drug Des Discov. 2014 Mar;11(3):331-338.

13.

Molecular docking studies and in vitro cholinesterase enzyme inhibitory activities of chemical constituents of Garcinia hombroniana.

Jamila N, Yeong KK, Murugaiyah V, Atlas A, Khan I, Khan N, Khan SN, Khairuddean M, Osman H.

Nat Prod Res. 2015;29(1):86-90. doi: 10.1080/14786419.2014.952228. Epub 2014 Sep 15.

PMID:
25219673
14.

Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman.

Gordon RK, Haigh JR, Garcia GE, Feaster SR, Riel MA, Lenz DE, Aisen PS, Doctor BP.

Chem Biol Interact. 2005 Dec 15;157-158:239-46. Epub 2005 Oct 26.

PMID:
16256090
15.

Syntheses, cholinesterases inhibition, and molecular docking studies of pyrido[2,3-b]pyrazine derivatives.

Hameed A, Zehra ST, Shah SJ, Khan KM, Alharthy RD, Furtmann N, Bajorath J, Tahir MN, Iqbal J.

Chem Biol Drug Des. 2015 Nov;86(5):1115-20. doi: 10.1111/cbdd.12579. Epub 2015 May 28.

PMID:
25951978
16.

Acetylcholinesterase and butyrylcholinesterase activities in obese Beagle dogs before and after weight loss.

Tvarijonaviciute A, Ceron JJ, Tecles F.

Vet Clin Pathol. 2013 Jun;42(2):207-11. doi: 10.1111/vcp.12032. Epub 2013 Apr 1.

PMID:
23550593
17.

Ionic liquid mediated synthesis of mono- and bis-spirooxindole-hexahydropyrrolidines as cholinesterase inhibitors and their molecular docking studies.

Kia Y, Osman H, Kumar RS, Basiri A, Murugaiyah V.

Bioorg Med Chem. 2014 Feb 15;22(4):1318-28. doi: 10.1016/j.bmc.2014.01.002. Epub 2014 Jan 9.

PMID:
24461561
18.
19.

Novel biphenyl bis-sulfonamides as acetyl and butyrylcholinesterase inhibitors: Synthesis, biological evaluation and molecular modeling studies.

Mutahir S, Jończyk J, Bajda M, Khan IU, Khan MA, Ullah N, Ashraf M, Qurat-ul-Ain, Riaz S, Hussain S, Yar M.

Bioorg Chem. 2016 Feb;64:13-20. doi: 10.1016/j.bioorg.2015.11.002. Epub 2015 Nov 10.

PMID:
26595185
20.

Naturally occurring variations in the human cholinesterase genes: heritability and association with cardiovascular and metabolic traits.

Valle AM, Radic Z, Rana BK, Mahboubi V, Wessel J, Shih PA, Rao F, O'Connor DT, Taylor P.

J Pharmacol Exp Ther. 2011 Jul;338(1):125-33. doi: 10.1124/jpet.111.180091. Epub 2011 Apr 14.

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