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Inhibition of proliferation and induction of autophagy by atorvastatin in PC3 prostate cancer cells correlate with downregulation of Bcl2 and upregulation of miR-182 and p21.

Peng X, Li W, Yuan L, Mehta RG, Kopelovich L, McCormick DL.

PLoS One. 2013 Aug 1;8(8):e70442. doi: 10.1371/journal.pone.0070442. Print 2013.


Statin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cells.

Parikh A, Childress C, Deitrick K, Lin Q, Rukstalis D, Yang W.

Prostate. 2010 Jun 15;70(9):971-81. doi: 10.1002/pros.21131.


Atorvastatin induces autophagy in prostate cancer PC3 cells through activation of LC3 transcription.

Toepfer N, Childress C, Parikh A, Rukstalis D, Yang W.

Cancer Biol Ther. 2011 Oct 15;12(8):691-9. doi: 10.4161/cbt.12.8.15978. Epub 2011 Oct 15.


Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer.

Amir S, Ma AH, Shi XB, Xue L, Kung HJ, Devere White RW.

PLoS One. 2013 Apr 9;8(4):e61064. doi: 10.1371/journal.pone.0061064. Print 2013.


Syndecan-1 responsive microRNA-126 and 149 regulate cell proliferation in prostate cancer.

Fujii T, Shimada K, Tatsumi Y, Fujimoto K, Konishi N.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):183-9. doi: 10.1016/j.bbrc.2014.11.056. Epub 2014 Nov 22.


Upregulation of MircoRNA-370 induces proliferation in human prostate cancer cells by downregulating the transcription factor FOXO1.

Wu Z, Sun H, Zeng W, He J, Mao X.

PLoS One. 2012;7(9):e45825. doi: 10.1371/journal.pone.0045825. Epub 2012 Sep 18.


Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer.

Wu Z, He B, He J, Mao X.

Prostate. 2013 May;73(6):596-604. doi: 10.1002/pros.22600. Epub 2012 Oct 11.


Cell killing and radiosensitizing effects of atorvastatin in PC3 prostate cancer cells.

He Z, Mangala LS, Theriot CA, Rohde LH, Wu H, Zhang Y.

J Radiat Res. 2012;53(2):225-33.


CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation.

Roca H, Varsos Z, Pienta KJ.

J Biol Chem. 2008 Sep 5;283(36):25057-73. doi: 10.1074/jbc.M801073200. Epub 2008 Jul 8.


MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer.

Verdoodt B, Neid M, Vogt M, Kuhn V, Liffers ST, Palisaar RJ, Noldus J, Tannapfel A, Mirmohammadsadegh A.

Int J Oncol. 2013 Jul;43(1):307-14. doi: 10.3892/ijo.2013.1915. Epub 2013 Apr 23.


TSA suppresses miR-106b-93-25 cluster expression through downregulation of MYC and inhibits proliferation and induces apoptosis in human EMC.

Zhao ZN, Bai JX, Zhou Q, Yan B, Qin WW, Jia LT, Meng YL, Jin BQ, Yao LB, Wang T, Yang AG.

PLoS One. 2012;7(9):e45133. doi: 10.1371/journal.pone.0045133. Epub 2012 Sep 19.


Piperine inhibits the proliferation of human prostate cancer cells via induction of cell cycle arrest and autophagy.

Ouyang DY, Zeng LH, Pan H, Xu LH, Wang Y, Liu KP, He XH.

Food Chem Toxicol. 2013 Oct;60:424-30. doi: 10.1016/j.fct.2013.08.007. Epub 2013 Aug 9.


Extended survivability of prostate cancer cells in the absence of trophic factors: increased proliferation, evasion of apoptosis, and the role of apoptosis proteins.

Tang DG, Li L, Chopra DP, Porter AT.

Cancer Res. 1998 Aug 1;58(15):3466-79. Erratum in: Cancer Res 1998 Nov 15;58(22):5260.


Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies.

Yang PM, Liu YL, Lin YC, Shun CT, Wu MS, Chen CC.

Cancer Res. 2010 Oct 1;70(19):7699-709. doi: 10.1158/0008-5472.CAN-10-1626. Epub 2010 Sep 28.


Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells.

Laurenzana A, Balliu M, Cellai C, Romanelli MN, Paoletti F.

PLoS One. 2013;8(3):e58267. doi: 10.1371/journal.pone.0058267. Epub 2013 Mar 4.


The pterocarpanquinone LQB-118 inhibits tumor cell proliferation by downregulation of c-Myc and cyclins D1 and B1 mRNA and upregulation of p21 cell cycle inhibitor expression.

Martino T, Magalhães FC, Justo GA, Coelho MG, Netto CD, Costa PR, Sabino KC.

Bioorg Med Chem. 2014 Jun 15;22(12):3115-22. doi: 10.1016/j.bmc.2014.04.025. Epub 2014 Apr 20.


miR-449a Regulates proliferation and chemosensitivity to cisplatin by targeting cyclin D1 and BCL2 in SGC7901 cells.

Hu J, Fang Y, Cao Y, Qin R, Chen Q.

Dig Dis Sci. 2014 Feb;59(2):336-45. doi: 10.1007/s10620-013-2923-3. Epub 2013 Nov 19.


Oridonin up-regulates expression of P21 and induces autophagy and apoptosis in human prostate cancer cells.

Li X, Li X, Wang J, Ye Z, Li JC.

Int J Biol Sci. 2012;8(6):901-12. doi: 10.7150/ijbs.4554. Epub 2012 Jun 22.


VEGFA Expression Is Inhibited by Arsenic Trioxide in HUVECs through the Upregulation of Ets-2 and miRNA-126.

Ge HY, Han ZJ, Tian P, Sun WJ, Xue DX, Bi Y, Yang ZH, Liu P.

PLoS One. 2015 Aug 14;10(8):e0135795. doi: 10.1371/journal.pone.0135795. eCollection 2015.

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