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Items: 1 to 20 of 178

1.

Five conditions commonly used to down-regulate tor complex 1 generate different physiological situations exhibiting distinct requirements and outcomes.

Tate JJ, Cooper TG.

J Biol Chem. 2013 Sep 20;288(38):27243-62. doi: 10.1074/jbc.M113.484386. Epub 2013 Aug 9.

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Nitrogen-responsive regulation of GATA protein family activators Gln3 and Gat1 occurs by two distinct pathways, one inhibited by rapamycin and the other by methionine sulfoximine.

Georis I, Tate JJ, Cooper TG, Dubois E.

J Biol Chem. 2011 Dec 30;286(52):44897-912. doi: 10.1074/jbc.M111.290577. Epub 2011 Oct 28.

4.

Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae.

Georis I, Tate JJ, Cooper TG, Dubois E.

J Biol Chem. 2008 Apr 4;283(14):8919-29. doi: 10.1074/jbc.M708811200. Epub 2008 Feb 1.

5.

Distinct phosphatase requirements and GATA factor responses to nitrogen catabolite repression and rapamycin treatment in Saccharomyces cerevisiae.

Tate JJ, Georis I, Dubois E, Cooper TG.

J Biol Chem. 2010 Jun 4;285(23):17880-95. doi: 10.1074/jbc.M109.085712. Epub 2010 Apr 8.

6.

GATA Factor Regulation in Excess Nitrogen Occurs Independently of Gtr-Ego Complex-Dependent TorC1 Activation.

Tate JJ, Georis I, Rai R, Vierendeels F, Dubois E, Cooper TG.

G3 (Bethesda). 2015 May 29;5(8):1625-38. doi: 10.1534/g3.115.019307.

7.

Alterations in the Ure2 ╬▒Cap domain elicit different GATA factor responses to rapamycin treatment and nitrogen limitation.

Feller A, Georis I, Tate JJ, Cooper TG, Dubois E.

J Biol Chem. 2013 Jan 18;288(3):1841-55. doi: 10.1074/jbc.M112.385054. Epub 2012 Nov 26.

8.

Sit4 and PP2A Dephosphorylate Nitrogen Catabolite Repression-Sensitive Gln3 When TorC1 Is Up- as Well as Downregulated.

Tate JJ, Tolley EA, Cooper TG.

Genetics. 2019 Aug;212(4):1205-1225. doi: 10.1534/genetics.119.302371. Epub 2019 Jun 18.

PMID:
31213504
9.

gln3 mutations dissociate responses to nitrogen limitation (nitrogen catabolite repression) and rapamycin inhibition of TorC1.

Rai R, Tate JJ, Nelson DR, Cooper TG.

J Biol Chem. 2013 Jan 25;288(4):2789-804. doi: 10.1074/jbc.M112.421826. Epub 2012 Dec 5.

10.

Methionine sulfoximine treatment and carbon starvation elicit Snf1-independent phosphorylation of the transcription activator Gln3 in Saccharomyces cerevisiae.

Tate JJ, Rai R, Cooper TG.

J Biol Chem. 2005 Jul 22;280(29):27195-204. Epub 2005 May 23. Erratum in: J Biol Chem. 2007 Apr 27;282(17):13139.

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Rapamycin-induced Gln3 dephosphorylation is insufficient for nuclear localization: Sit4 and PP2A phosphatases are regulated and function differently.

Tate JJ, Georis I, Feller A, Dubois E, Cooper TG.

J Biol Chem. 2009 Jan 23;284(4):2522-34. doi: 10.1074/jbc.M806162200. Epub 2008 Nov 17.

14.

Nitrogen catabolite repression-sensitive transcription as a readout of Tor pathway regulation: the genetic background, reporter gene and GATA factor assayed determine the outcomes.

Georis I, Feller A, Tate JJ, Cooper TG, Dubois E.

Genetics. 2009 Mar;181(3):861-74. doi: 10.1534/genetics.108.099051. Epub 2008 Dec 22. Erratum in: Genetics. 2009 Jul;182(3):927.

15.

More than One Way in: Three Gln3 Sequences Required To Relieve Negative Ure2 Regulation and Support Nuclear Gln3 Import in Saccharomyces cerevisiae.

Tate JJ, Rai R, Cooper TG.

Genetics. 2018 Jan;208(1):207-227. doi: 10.1534/genetics.117.300457. Epub 2017 Nov 7.

16.

A domain in the transcription activator Gln3 specifically required for rapamycin responsiveness.

Rai R, Tate JJ, Shanmuganatham K, Howe MM, Cooper TG.

J Biol Chem. 2014 Jul 4;289(27):18999-9018. doi: 10.1074/jbc.M114.563668. Epub 2014 May 20.

19.

General Amino Acid Control and 14-3-3 Proteins Bmh1/2 Are Required for Nitrogen Catabolite Repression-Sensitive Regulation of Gln3 and Gat1 Localization.

Tate JJ, Buford D, Rai R, Cooper TG.

Genetics. 2017 Feb;205(2):633-655. doi: 10.1534/genetics.116.195800. Epub 2016 Dec 22.

20.

The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine.

Crespo JL, Powers T, Fowler B, Hall MN.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6784-9. Epub 2002 May 7.

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