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Items: 1 to 20 of 178

1.

Synthesis and biological evaluation of 1,2,4-triazole and 1,3,4-thiadiazole derivatives as potential cytotoxic agents.

Shi YJ, Song XJ, Li X, Ye TH, Xiong Y, Yu LT.

Chem Pharm Bull (Tokyo). 2013;61(11):1099-104. Epub 2013 Aug 10.

2.

Synthesis and cytotoxicity of 3,4-disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and novel 5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives bearing 3,4,5-trimethoxyphenyl moiety.

Zhao PL, Duan AN, Zou M, Yang HK, You WW, Wu SG.

Bioorg Med Chem Lett. 2012 Jul 1;22(13):4471-4. doi: 10.1016/j.bmcl.2012.03.023. Epub 2012 Mar 11. Erratum in: Bioorg Med Chem Lett. 2015 Sep 1;25(17):3754.

PMID:
22647723
3.

Synthesis and antiproliferative activity of some new thieno[2,3-d]pyrimidin-4(3H)-ones containing 1,2,4-triazole and 1,3,4-thiadiazole moiety.

Mavrova ATs, Wesselinova D, Tsenov JA, Lubenov LA.

Eur J Med Chem. 2014 Oct 30;86:676-83. doi: 10.1016/j.ejmech.2014.09.032. Epub 2014 Sep 10.

PMID:
25222878
4.

Synthesis and biological evaluation of novel isoxazoles and triazoles linked 6-hydroxycoumarin as potent cytotoxic agents.

Shakeel-u-Rehman, Masood-ur-Rahman, Tripathi VK, Singh J, Ara T, Koul S, Farooq S, Kaul A.

Bioorg Med Chem Lett. 2014 Sep 1;24(17):4243-6. doi: 10.1016/j.bmcl.2014.07.031. Epub 2014 Jul 17.

PMID:
25088398
5.

Synthesis and biological evaluation of 3,6-disubstituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as a novel class of potential anti-tumor agents.

Ibrahim DA.

Eur J Med Chem. 2009 Jul;44(7):2776-81. doi: 10.1016/j.ejmech.2009.01.003. Epub 2009 Jan 19.

PMID:
19203813
6.

Cytotoxicity of new 5-phenyl-4,5-dihydro-1,3,4-thiadiazole analogues.

Alam MS, Liu L, Lee DU.

Chem Pharm Bull (Tokyo). 2011;59(11):1413-6.

7.

Synthesis and antitumor-evaluation of 1,3-selenazole-containing 1,3,4-thiadiazole derivatives.

Zhao HC, Shi YP, Liu YM, Li CW, Xuan LN, Wang P, Zhang K, Chen BQ.

Bioorg Med Chem Lett. 2013 Dec 15;23(24):6577-9. doi: 10.1016/j.bmcl.2013.10.062. Epub 2013 Nov 6.

PMID:
24239016
8.

Synthesis of novel indolyl-1,2,4-triazoles as potent and selective anticancer agents.

Kumar D, Narayanam MK, Chang KH, Shah K.

Chem Biol Drug Des. 2011 Mar;77(3):182-8. doi: 10.1111/j.1747-0285.2010.01051.x. Epub 2011 Jan 19.

PMID:
21251232
9.

Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: design and synthesis as anticancer agents.

Husain A, Rashid M, Mishra R, Parveen S, Shin DS, Kumar D.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5438-44. doi: 10.1016/j.bmcl.2012.07.038. Epub 2012 Jul 17.

PMID:
22840417
10.

Synthesis and biological evaluation of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxins as potential anticancer agents.

Reddy PB, Agrawal SK, Singh S, Bhat BA, Saxena AK, Kumar HM, Qazi GN.

Chem Biodivers. 2008 Sep;5(9):1792-802. doi: 10.1002/cbdv.200890168.

PMID:
18816530
11.

Benzimidazole clubbed with triazolo-thiadiazoles and triazolo-thiadiazines: new anticancer agents.

Husain A, Rashid M, Shaharyar M, Siddiqui AA, Mishra R.

Eur J Med Chem. 2013 Apr;62:785-98. doi: 10.1016/j.ejmech.2012.07.011. Epub 2012 Jul 16.

PMID:
23333063
12.

Synthesis and anticancer activity of 5-(3-indolyl)-1,3,4-thiadiazoles.

Kumar D, Maruthi Kumar N, Chang KH, Shah K.

Eur J Med Chem. 2010 Oct;45(10):4664-8. doi: 10.1016/j.ejmech.2010.07.023. Epub 2010 Jul 21.

PMID:
20692741
13.
14.

Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4'-fluorophenyl)-imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent anticancer agents.

Karki SS, Panjamurthy K, Kumar S, Nambiar M, Ramareddy SA, Chiruvella KK, Raghavan SC.

Eur J Med Chem. 2011 Jun;46(6):2109-16. doi: 10.1016/j.ejmech.2011.02.064. Epub 2011 Mar 4.

PMID:
21439690
15.

Synthesis of Novel 2,5-Disubstituted-1,3,4-thiadiazoles Clubbed 1,2,4-Triazole, 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and/or Schiff Base as Potential Antimicrobial and Antiproliferative Agents.

Rezki N, Al-Yahyawi AM, Bardaweel SK, Al-Blewi FF, Aouad MR.

Molecules. 2015 Sep 2;20(9):16048-67. doi: 10.3390/molecules200916048.

16.

Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of fused [1,3,4]thiadiazoles.

El-Gohary NS, Shaaban MI.

Eur J Med Chem. 2013 May;63:185-95. doi: 10.1016/j.ejmech.2013.02.010. Epub 2013 Feb 18.

PMID:
23474904
17.

Synthesis and structure-activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid.

Santos RC, Salvador JA, Marín S, Cascante M, Moreira JN, Dinis TC.

Bioorg Med Chem. 2010 Jun 15;18(12):4385-96. doi: 10.1016/j.bmc.2010.04.085. Epub 2010 Apr 29.

PMID:
20494586
18.

An efficient one-pot synthesis of heterocycle-fused 1,2,3-triazole derivatives as anti-cancer agents.

Yan SJ, Liu YJ, Chen YL, Liu L, Lin J.

Bioorg Med Chem Lett. 2010 Sep 1;20(17):5225-8. doi: 10.1016/j.bmcl.2010.06.141. Epub 2010 Jul 23.

PMID:
20655212
19.
20.

Synthesis and anticancer evaluation of novel 2-cyclopropylimidazo[2,1-b][1,3,4]-thiadiazole derivatives.

Noolvi MN, Patel HM, Singh N, Gadad AK, Cameotra SS, Badiger A.

Eur J Med Chem. 2011 Sep;46(9):4411-8. doi: 10.1016/j.ejmech.2011.07.012. Epub 2011 Jul 8.

PMID:
21820217

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