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Items: 1 to 20 of 105

1.

Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered NR4A2 activity.

McMorrow JP, Crean D, Gogarty M, Smyth A, Connolly M, Cummins E, Veale D, Fearon U, Tak PP, Fitzgerald O, Murphy EP.

Am J Pathol. 2013 Oct;183(4):1243-57. doi: 10.1016/j.ajpath.2013.06.029. Epub 2013 Aug 6.

PMID:
23933487
2.

Orphan nuclear receptor NR4A2 induces synoviocyte proliferation, invasion, and matrix metalloproteinase 13 transcription.

Mix KS, McMahon K, McMorrow JP, Walkenhorst DE, Smyth AM, Petrella BL, Gogarty M, Fearon U, Veale D, Attur MG, Abramson SB, Murphy EP.

Arthritis Rheum. 2012 Jul;64(7):2126-36. doi: 10.1002/art.34399.

3.

Identification of NR4A2 as a transcriptional activator of IL-8 expression in human inflammatory arthritis.

Aherne CM, McMorrow J, Kane D, FitzGerald O, Mix KS, Murphy EP.

Mol Immunol. 2009 Oct;46(16):3345-57. doi: 10.1016/j.molimm.2009.07.019. Epub 2009 Sep 3.

PMID:
19732956
4.
5.

Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression.

Cho ML, Min SY, Chang SH, Kim KW, Heo SB, Lee SH, Park SH, Cho CS, Kim HY.

Immunol Lett. 2006 Jun 15;105(2):159-66. Epub 2006 Mar 3.

PMID:
16564576
6.
7.

Interleukin-18 induces the production of vascular endothelial growth factor (VEGF) in rheumatoid arthritis synovial fibroblasts via AP-1-dependent pathways.

Cho ML, Jung YO, Moon YM, Min SY, Yoon CH, Lee SH, Park SH, Cho CS, Jue DM, Kim HY.

Immunol Lett. 2006 Mar 15;103(2):159-66. Epub 2005 Nov 16.

PMID:
16368150
8.

Toll-like receptor 2 ligand mediates the upregulation of angiogenic factor, vascular endothelial growth factor and interleukin-8/CXCL8 in human rheumatoid synovial fibroblasts.

Cho ML, Ju JH, Kim HR, Oh HJ, Kang CM, Jhun JY, Lee SY, Park MK, Min JK, Park SH, Lee SH, Kim HY.

Immunol Lett. 2007 Feb 15;108(2):121-8. Epub 2006 Dec 11.

PMID:
17182109
9.

Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1.

Grall F, Gu X, Tan L, Cho JY, Inan MS, Pettit AR, Thamrongsak U, Choy BK, Manning C, Akbarali Y, Zerbini L, Rudders S, Goldring SR, Gravallese EM, Oettgen P, Goldring MB, Libermann TA.

Arthritis Rheum. 2003 May;48(5):1249-60.

10.

Tumor necrosis factor-alpha induces vascular endothelial growth factor-C expression in rheumatoid synoviocytes.

Cha HS, Bae EK, Koh JH, Chai JY, Jeon CH, Ahn KS, Kim J, Koh EM.

J Rheumatol. 2007 Jan;34(1):16-9.

PMID:
17216674
11.
12.

Macrophage migration inhibitory factor upregulates angiogenic factors and correlates with clinical measures in rheumatoid arthritis.

Kim HR, Park MK, Cho ML, Yoon CH, Lee SH, Park SH, Leng L, Bucala R, Kang I, Choe J, Kim HY.

J Rheumatol. 2007 May;34(5):927-36. Epub 2007 Apr 1.

PMID:
17407222
13.

Citrullinated vimentin stimulates proliferation, pro-inflammatory cytokine secretion, and PADI4 and RANKL expression of fibroblast-like synoviocytes in rheumatoid arthritis.

Fan LY, He DY, Wang Q, Zong M, Zhang H, Yang L, Sun LS.

Scand J Rheumatol. 2012 Oct;41(5):354-8. doi: 10.3109/03009742.2012.670263. Epub 2012 Jul 5.

PMID:
22765310
14.

Interleukin (IL)-23 p19 expression induced by IL-1beta in human fibroblast-like synoviocytes with rheumatoid arthritis via active nuclear factor-kappaB and AP-1 dependent pathway.

Liu FL, Chen CH, Chu SJ, Chen JH, Lai JH, Sytwu HK, Chang DM.

Rheumatology (Oxford). 2007 Aug;46(8):1266-73. Epub 2007 Jun 14.

PMID:
17569750
15.

Upregulation of Thrombospondin 1 Expression in Synovial Tissues and Plasma of Rheumatoid Arthritis: Role of Transforming Growth Factor-β1 toward Fibroblast-like Synovial Cells.

Suzuki T, Iwamoto N, Yamasaki S, Nishino A, Nakashima Y, Horai Y, Kawashiri SY, Ichinose K, Arima K, Tamai M, Nakamura H, Origuchi T, Miyamoto C, Osaki M, Ohyama K, Kuroda N, Kawakami A.

J Rheumatol. 2015 Jun;42(6):943-7. doi: 10.3899/jrheum.141292. Epub 2015 May 1.

PMID:
25934826
16.

Interleukin-18 induces angiogenic factors in rheumatoid arthritis synovial tissue fibroblasts via distinct signaling pathways.

Amin MA, Mansfield PJ, Pakozdi A, Campbell PL, Ahmed S, Martinez RJ, Koch AE.

Arthritis Rheum. 2007 Jun;56(6):1787-97.

17.

Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis.

Nakahara H, Song J, Sugimoto M, Hagihara K, Kishimoto T, Yoshizaki K, Nishimoto N.

Arthritis Rheum. 2003 Jun;48(6):1521-9.

18.

NF-kappaB blockade upregulates Bax, TSP-1, and TSP-2 expression in rat granulation tissue.

De Stefano D, Nicolaus G, Maiuri MC, Cipolletta D, Galluzzi L, Cinelli MP, Tajana G, Iuvone T, Carnuccio R.

J Mol Med (Berl). 2009 May;87(5):481-92. doi: 10.1007/s00109-009-0443-6. Epub 2009 Feb 3.

PMID:
19189070
19.

Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor alpha and interleukin-1 in rheumatoid arthritis.

Paleolog EM, Young S, Stark AC, McCloskey RV, Feldmann M, Maini RN.

Arthritis Rheum. 1998 Jul;41(7):1258-65.

PMID:
9663484
20.

Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium.

Hou WS, Li W, Keyszer G, Weber E, Levy R, Klein MJ, Gravallese EM, Goldring SR, Brömme D.

Arthritis Rheum. 2002 Mar;46(3):663-74.

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