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Items: 1 to 20 of 118

1.

The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage.

Abu Lila AS, Kiwada H, Ishida T.

J Control Release. 2013 Nov 28;172(1):38-47. doi: 10.1016/j.jconrel.2013.07.026. Epub 2013 Aug 7. Review.

PMID:
23933235
2.

Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration.

Abu Lila AS, Nawata K, Shimizu T, Ishida T, Kiwada H.

Int J Pharm. 2013 Nov 1;456(1):235-42. doi: 10.1016/j.ijpharm.2013.07.059. Epub 2013 Aug 5.

PMID:
23928149
3.

Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes.

Ishida T, Kiwada H.

Int J Pharm. 2008 Apr 16;354(1-2):56-62. Epub 2007 Nov 9. Review.

PMID:
18083313
4.

[Recent advances in the study of accelerated blood clearance phenomenon of PEGylated liposomes].

Xu H, Wang KQ, Huang WW, Deng YH, Chen DW.

Yao Xue Xue Bao. 2010 Jun;45(6):677-83. Review. Chinese.

PMID:
20939173
5.

Transport of PEGylated liposomes from the splenic marginal zone to the follicle in the induction phase of the accelerated blood clearance phenomenon.

Shimizu T, Ishida T, Kiwada H.

Immunobiology. 2013 May;218(5):725-32. doi: 10.1016/j.imbio.2012.08.274. Epub 2012 Aug 23.

PMID:
22995937
6.
7.

Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes.

Ishida T, Ichihara M, Wang X, Kiwada H.

J Control Release. 2006 Oct 27;115(3):243-50. Epub 2006 Aug 7.

PMID:
17011060
8.

[Elucidation of accelerated blood clearance phenomenon caused by repeat injection of PEGylated nanocarriers].

Koide H, Asai T, Hatanaka K, Shimizu K, Yokoyama M, Ishida T, Kiwada H, Oku N.

Yakugaku Zasshi. 2009 Dec;129(12):1445-51. Review. Japanese.

9.

[Accelerated blood clearance (ABC) phenomenon induced by administration of PEGylated liposome].

Ishida T, Kiwada H.

Yakugaku Zasshi. 2008 Feb;128(2):233-43. Review. Japanese.

10.
11.

T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes.

Koide H, Asai T, Hatanaka K, Akai S, Ishii T, Kenjo E, Ishida T, Kiwada H, Tsukada H, Oku N.

Int J Pharm. 2010 Jun 15;392(1-2):218-23. doi: 10.1016/j.ijpharm.2010.03.022. Epub 2010 Mar 21.

PMID:
20227473
12.

Accelerated blood clearance of pegylated liposomal topotecan: influence of polyethylene glycol grafting density and animal species.

Li C, Cao J, Wang Y, Zhao X, Deng C, Wei N, Yang J, Cui J.

J Pharm Sci. 2012 Oct;101(10):3864-76. doi: 10.1002/jps.23254. Epub 2012 Jul 6.

PMID:
22777607
13.

Repeated injection of PEGylated solid lipid nanoparticles induces accelerated blood clearance in mice and beagles.

Zhao Y, Wang L, Yan M, Ma Y, Zang G, She Z, Deng Y.

Int J Nanomedicine. 2012;7:2891-900. doi: 10.2147/IJN.S30943. Epub 2012 Jun 12.

14.

Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes with splenic marginal zone B cells.

Shimizu T, Mima Y, Hashimoto Y, Ukawa M, Ando H, Kiwada H, Ishida T.

Immunobiology. 2015 Oct;220(10):1151-60. doi: 10.1016/j.imbio.2015.06.005. Epub 2015 Jun 6.

PMID:
26095176
15.

Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs.

Hashimoto Y, Shimizu T, Mima Y, Abu Lila AS, Ishida T, Kiwada H.

Toxicol Appl Pharmacol. 2014 May 15;277(1):30-8. doi: 10.1016/j.taap.2014.03.002. Epub 2014 Mar 12.

PMID:
24632081
16.

Anti-PEG IgM Is a Major Contributor to the Accelerated Blood Clearance of Polyethylene Glycol-Conjugated Protein.

Mima Y, Hashimoto Y, Shimizu T, Kiwada H, Ishida T.

Mol Pharm. 2015 Jul 6;12(7):2429-35. doi: 10.1021/acs.molpharmaceut.5b00144. Epub 2015 Jun 24.

PMID:
26070445
17.

Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes.

Wang X, Ishida T, Kiwada H.

J Control Release. 2007 Jun 4;119(2):236-44. Epub 2007 Feb 24.

PMID:
17399838
18.

Hemoglobin vesicles, polyethylene glycol (PEG)ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice.

Taguchi K, Urata Y, Anraku M, Watanabe H, Kadowaki D, Sakai H, Horinouchi H, Kobayashi K, Tsuchida E, Maruyama T, Otagiri M.

Drug Metab Dispos. 2009 Nov;37(11):2197-203. doi: 10.1124/dmd.109.028852. Epub 2009 Aug 13.

19.

Accelerated blood clearance of PEGylated liposomes upon repeated injections: effect of doxorubicin-encapsulation and high-dose first injection.

Ishida T, Atobe K, Wang X, Kiwada H.

J Control Release. 2006 Oct 27;115(3):251-8. Epub 2006 Sep 3.

PMID:
17045355
20.

Prolongation of time interval between doses could eliminate accelerated blood clearance phenomenon induced by pegylated liposomal topotecan.

Li C, Zhao X, Wang Y, Yang H, Li H, Li H, Tian W, Yang J, Cui J.

Int J Pharm. 2013 Feb 25;443(1-2):17-25. doi: 10.1016/j.ijpharm.2013.01.012. Epub 2013 Jan 11.

PMID:
23318366

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