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Items: 1 to 20 of 73

1.

The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis.

Subramani A, Alsidawi S, Jagannathan S, Sumita K, Sasaki AT, Aronow B, Warnick RE, Lawler S, Driscoll JJ.

Sci Rep. 2013;3:2392. doi: 10.1038/srep02392.

2.

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.

Zhang L, Zhang S, Yao J, Lowery FJ, Zhang Q, Huang WC, Li P, Li M, Wang X, Zhang C, Wang H, Ellis K, Cheerathodi M, McCarty JH, Palmieri D, Saunus J, Lakhani S, Huang S, Sahin AA, Aldape KD, Steeg PS, Yu D.

Nature. 2015 Nov 5;527(7576):100-104. doi: 10.1038/nature15376. Epub 2015 Oct 19.

3.

Group IIa secretory phospholipase expression correlates with group IIa secretory phospholipase inhibition-mediated cell death in K-ras mutant lung cancer cells.

Yu JA, Li H, Meng X, Fullerton DA, Nemenoff RA, Mitchell JD, Weyant MJ.

J Thorac Cardiovasc Surg. 2012 Dec;144(6):1479-85. doi: 10.1016/j.jtcvs.2012.08.064. Epub 2012 Sep 29.

4.

MicroRNA let-7a inhibits the proliferation and invasion of nonsmall cell lung cancer cell line 95D by regulating K-Ras and HMGA2 gene expression.

Wang YY, Ren T, Cai YY, He XY.

Cancer Biother Radiopharm. 2013 Mar;28(2):131-7. doi: 10.1089/cbr.2012.1307. Epub 2012 Nov 7.

PMID:
23134218
5.

Galectin-3 promotes chronic activation of K-Ras and differentiation block in malignant thyroid carcinomas.

Levy R, Grafi-Cohen M, Kraiem Z, Kloog Y.

Mol Cancer Ther. 2010 Aug;9(8):2208-19. doi: 10.1158/1535-7163.MCT-10-0262. Epub 2010 Aug 3.

6.

MiRNA-125a-3p is a negative regulator of the RhoA-actomyosin pathway in A549 cells.

Huang B, Luo W, Sun L, Zhang Q, Jiang L, Chang J, Qiu X, Wang E.

Int J Oncol. 2013 May;42(5):1734-42. doi: 10.3892/ijo.2013.1861. Epub 2013 Mar 21.

PMID:
23525486
7.

Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells.

Jiang L, Huang Q, Zhang S, Zhang Q, Chang J, Qiu X, Wang E.

BMC Cancer. 2010 Jun 22;10:318. doi: 10.1186/1471-2407-10-318.

8.
9.

Overexpression of microRNA-95-3p suppresses brain metastasis of lung adenocarcinoma through downregulation of cyclin D1.

Hwang SJ, Lee HW, Kim HR, Song HJ, Lee DH, Lee H, Shin CH, Joung JG, Kim DH, Joo KM, Kim HH.

Oncotarget. 2015 Aug 21;6(24):20434-48.

10.

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.

Kumar MS, Hancock DC, Molina-Arcas M, Steckel M, East P, Diefenbacher M, Armenteros-Monterroso E, Lassailly F, Matthews N, Nye E, Stamp G, Behrens A, Downward J.

Cell. 2012 Apr 27;149(3):642-55. doi: 10.1016/j.cell.2012.02.059.

11.

Hepatocellular carcinoma with persistent hepatitis B virus infection shows unusual downregulation of Ras expression and differential response to Ras mediated signaling.

Bose S, Sakhuja P, Bezawada L, Agarwal AK, Kazim SN, Khan LA, Sarin SK, Ramakrishna G.

J Gastroenterol Hepatol. 2011 Jan;26(1):135-44. doi: 10.1111/j.1440-1746.2010.06305.x.

PMID:
21175807
12.

MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol.

Han Z, Yang Q, Liu B, Wu J, Li Y, Yang C, Jiang Y.

Carcinogenesis. 2012 Jan;33(1):131-9. doi: 10.1093/carcin/bgr226. Epub 2011 Oct 19.

PMID:
22016468
13.

microRNA-338-3p functions as a tumor suppressor in human non‑small‑cell lung carcinoma and targets Ras-related protein 14.

Sun J, Feng X, Gao S, Xiao Z.

Mol Med Rep. 2015 Feb;11(2):1400-6. doi: 10.3892/mmr.2014.2880. Epub 2014 Nov 6.

PMID:
25374067
14.

Comprehensive gene and microRNA expression profiling reveals miR-206 inhibits MET in lung cancer metastasis.

Chen QY, Jiao DM, Yan L, Wu YQ, Hu HZ, Song J, Yan J, Wu LJ, Xu LQ, Shi JG.

Mol Biosyst. 2015 Aug;11(8):2290-302. doi: 10.1039/c4mb00734d.

PMID:
26075299
15.

Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer.

Han HB, Gu J, Zuo HJ, Chen ZG, Zhao W, Li M, Ji DB, Lu YY, Zhang ZQ.

J Pathol. 2012 Feb;226(3):544-55. doi: 10.1002/path.3014. Epub 2011 Dec 5.

PMID:
21984339
16.

MicroRNA-19a-3p inhibits breast cancer progression and metastasis by inducing macrophage polarization through downregulated expression of Fra-1 proto-oncogene.

Yang J, Zhang Z, Chen C, Liu Y, Si Q, Chuang TH, Li N, Gomez-Cabrero A, Reisfeld RA, Xiang R, Luo Y.

Oncogene. 2014 Jun 5;33(23):3014-23. doi: 10.1038/onc.2013.258. Epub 2013 Jul 8.

PMID:
23831570
17.

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.

Loboda A, Nebozhyn M, Klinghoffer R, Frazier J, Chastain M, Arthur W, Roberts B, Zhang T, Chenard M, Haines B, Andersen J, Nagashima K, Paweletz C, Lynch B, Feldman I, Dai H, Huang P, Watters J.

BMC Med Genomics. 2010 Jun 30;3:26. doi: 10.1186/1755-8794-3-26.

18.

miR-34c-3p functions as a tumour suppressor by inhibiting eIF4E expression in non-small cell lung cancer.

Liu F, Wang X, Li J, Gu K, Lv L, Zhang S, Che D, Cao J, Jin S, Yu Y.

Cell Prolif. 2015 Oct;48(5):582-92. doi: 10.1111/cpr.12201. Epub 2015 Aug 6.

PMID:
26250586
19.

Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer.

Pichler M, Winter E, Stotz M, Eberhard K, Samonigg H, Lax S, Hoefler G.

Br J Cancer. 2012 May 22;106(11):1826-32. doi: 10.1038/bjc.2012.175. Epub 2012 May 1.

20.

MicroRNA-217 functions as a tumour suppressor gene and correlates with cell resistance to cisplatin in lung cancer.

Guo J, Feng Z, Huang Z, Wang H, Lu W.

Mol Cells. 2014 Sep;37(9):664-71. doi: 10.14348/molcells.2014.0121. Epub 2014 Sep 18.

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