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Items: 1 to 20 of 166

1.

Protection of spiral ganglion neurons from degeneration using small-molecule TrkB receptor agonists.

Yu Q, Chang Q, Liu X, Wang Y, Li H, Gong S, Ye K, Lin X.

J Neurosci. 2013 Aug 7;33(32):13042-52. doi: 10.1523/JNEUROSCI.0854-13.2013.

2.

7,8,3'-Trihydroxyflavone, a potent small molecule TrkB receptor agonist, protects spiral ganglion neurons from degeneration both in vitro and in vivo.

Yu Q, Chang Q, Liu X, Gong S, Ye K, Lin X.

Biochem Biophys Res Commun. 2012 Jun 8;422(3):387-92. doi: 10.1016/j.bbrc.2012.04.154. Epub 2012 May 7.

3.

Spiral ganglion neuron survival and function in the deafened cochlea following chronic neurotrophic treatment.

Landry TG, Wise AK, Fallon JB, Shepherd RK.

Hear Res. 2011 Dec;282(1-2):303-13. doi: 10.1016/j.heares.2011.06.007. Epub 2011 Jul 6.

4.

Connexin 26 null mice exhibit spiral ganglion degeneration that can be blocked by BDNF gene therapy.

Takada Y, Beyer LA, Swiderski DL, O'Neal AL, Prieskorn DM, Shivatzki S, Avraham KB, Raphael Y.

Hear Res. 2014 Mar;309:124-35. doi: 10.1016/j.heares.2013.11.009. Epub 2013 Dec 12.

6.

The effect of deafness duration on neurotrophin gene therapy for spiral ganglion neuron protection.

Wise AK, Tu T, Atkinson PJ, Flynn BO, Sgro BE, Hume C, O'Leary SJ, Shepherd RK, Richardson RT.

Hear Res. 2011 Aug;278(1-2):69-76. doi: 10.1016/j.heares.2011.04.010. Epub 2011 May 1.

8.
9.

Type I vs type II spiral ganglion neurons exhibit differential survival and neuritogenesis during cochlear development.

Barclay M, Ryan AF, Housley GD.

Neural Dev. 2011 Oct 11;6:33. doi: 10.1186/1749-8104-6-33.

10.

Neurotrophins and electrical stimulation for protection and repair of spiral ganglion neurons following sensorineural hearing loss.

Shepherd RK, Coco A, Epp SB.

Hear Res. 2008 Aug;242(1-2):100-9. doi: 10.1016/j.heares.2007.12.005. Epub 2007 Dec 28.

11.

Delayed electrical stimulation and BDNF application following induced deafness in rats.

Song BN, Li YX, Han DM.

Acta Otolaryngol. 2009 Feb;129(2):142-54. doi: 10.1080/00016480802043949.

PMID:
18607918
12.

Enhanced survival of spiral ganglion cells after cessation of treatment with brain-derived neurotrophic factor in deafened guinea pigs.

Agterberg MJ, Versnel H, van Dijk LM, de Groot JC, Klis SF.

J Assoc Res Otolaryngol. 2009 Sep;10(3):355-67. doi: 10.1007/s10162-009-0170-2. Epub 2009 Apr 14.

13.

EphA7 regulates spiral ganglion innervation of cochlear hair cells.

Kim YJ, Ibrahim LA, Wang SZ, Yuan W, Evgrafov OV, Knowles JA, Wang K, Tao HW, Zhang LI.

Dev Neurobiol. 2016 Apr;76(4):452-69. doi: 10.1002/dneu.22326. Epub 2015 Jul 27.

14.

Improved Auditory Nerve Survival with Nanoengineered Supraparticles for Neurotrophin Delivery into the Deafened Cochlea.

Wise AK, Tan J, Wang Y, Caruso F, Shepherd RK.

PLoS One. 2016 Oct 27;11(10):e0164867. doi: 10.1371/journal.pone.0164867. eCollection 2016.

15.

Developmental changes in the responsiveness of rat spiral ganglion neurons to neurotrophic factors in dissociated culture: differential responses for survival, neuritogenesis and neuronal morphology.

Jin Y, Kondo K, Ushio M, Kaga K, Ryan AF, Yamasoba T.

Cell Tissue Res. 2013 Jan;351(1):15-27. doi: 10.1007/s00441-012-1526-1. Epub 2012 Nov 13.

16.

Exogenous BDNF rescues rat spiral ganglion neurons in vivo.

McGuinness SL, Shepherd RK.

Otol Neurotol. 2005 Sep;26(5):1064-72.

17.

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.

Jang SW, Liu X, Yepes M, Shepherd KR, Miller GW, Liu Y, Wilson WD, Xiao G, Blanchi B, Sun YE, Ye K.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2687-92. doi: 10.1073/pnas.0913572107. Epub 2010 Jan 25.

18.

The Trk A, B, C's of neurotrophins in the cochlea.

Green SH, Bailey E, Wang Q, Davis RL.

Anat Rec (Hoboken). 2012 Nov;295(11):1877-95. doi: 10.1002/ar.22587. Epub 2012 Oct 8. Review.

19.

Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.

Lv P, Kim HJ, Lee JH, Sihn CR, Fathabad Gharaie S, Mousavi-Nik A, Wang W, Wang HG, Gratton MA, Doyle KJ, Zhang XD, Chiamvimonvat N, Yamoah EN.

J Neurosci. 2014 May 21;34(21):7383-93. doi: 10.1523/JNEUROSCI.5416-13.2014.

20.

Changes in responsiveness of rat spiral ganglion neurons to neurotrophins across age: differential regulation of survival and neuritogenesis.

Kondo K, Pak K, Chavez E, Mullen L, Euteneuer S, Ryan AF.

Int J Neurosci. 2013 Jul;123(7):465-75. doi: 10.3109/00207454.2013.764497. Epub 2013 Feb 11.

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