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Items: 1 to 20 of 166

1.

Type 2 innate lymphoid cells constitutively express arginase-I in the naive and inflamed lung.

Bando JK, Nussbaum JC, Liang HE, Locksley RM.

J Leukoc Biol. 2013 Nov;94(5):877-84. doi: 10.1189/jlb.0213084. Epub 2013 Aug 7.

2.

Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production.

Doherty TA, Khorram N, Lund S, Mehta AK, Croft M, Broide DH.

J Allergy Clin Immunol. 2013 Jul;132(1):205-13. doi: 10.1016/j.jaci.2013.03.048. Epub 2013 May 17.

3.

IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation.

Turner JE, Morrison PJ, Wilhelm C, Wilson M, Ahlfors H, Renauld JC, Panzer U, Helmby H, Stockinger B.

J Exp Med. 2013 Dec 16;210(13):2951-65. doi: 10.1084/jem.20130071. Epub 2013 Nov 18.

4.

Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma.

Klein Wolterink RG, Kleinjan A, van Nimwegen M, Bergen I, de Bruijn M, Levani Y, Hendriks RW.

Eur J Immunol. 2012 May;42(5):1106-16. doi: 10.1002/eji.201142018.

5.

Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis.

Mohapatra A, Van Dyken SJ, Schneider C, Nussbaum JC, Liang HE, Locksley RM.

Mucosal Immunol. 2016 Jan;9(1):275-86. doi: 10.1038/mi.2015.59. Epub 2015 Jul 1.

6.

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.

Monticelli LA, Buck MD, Flamar AL, Saenz SA, Tait Wojno ED, Yudanin NA, Osborne LC, Hepworth MR, Tran SV, Rodewald HR, Shah H, Cross JR, Diamond JM, Cantu E, Christie JD, Pearce EL, Artis D.

Nat Immunol. 2016 Jun;17(6):656-65. doi: 10.1038/ni.3421. Epub 2016 Apr 4.

7.
8.

Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1.

Spooner CJ, Lesch J, Yan D, Khan AA, Abbas A, Ramirez-Carrozzi V, Zhou M, Soriano R, Eastham-Anderson J, Diehl L, Lee WP, Modrusan Z, Pappu R, Xu M, DeVoss J, Singh H.

Nat Immunol. 2013 Dec;14(12):1229-36. doi: 10.1038/ni.2743. Epub 2013 Oct 20.

PMID:
24141388
9.

IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation.

Roediger B, Kyle R, Tay SS, Mitchell AJ, Bolton HA, Guy TV, Tan SY, Forbes-Blom E, Tong PL, Köller Y, Shklovskaya E, Iwashima M, McCoy KD, Le Gros G, Fazekas de St Groth B, Weninger W.

J Allergy Clin Immunol. 2015 Dec;136(6):1653-1663.e7. doi: 10.1016/j.jaci.2015.03.043. Epub 2015 May 27.

PMID:
26025126
10.

Intrinsic functional defects of type 2 innate lymphoid cells impair innate allergic inflammation in promyelocytic leukemia zinc finger (PLZF)-deficient mice.

Verhoef PA, Constantinides MG, McDonald BD, Urban JF Jr, Sperling AI, Bendelac A.

J Allergy Clin Immunol. 2016 Feb;137(2):591-600.e1. doi: 10.1016/j.jaci.2015.07.050. Epub 2015 Oct 23.

11.

Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation.

Molofsky AB, Van Gool F, Liang HE, Van Dyken SJ, Nussbaum JC, Lee J, Bluestone JA, Locksley RM.

Immunity. 2015 Jul 21;43(1):161-74. doi: 10.1016/j.immuni.2015.05.019. Epub 2015 Jun 16.

12.

Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation.

Lund SJ, Portillo A, Cavagnero K, Baum RE, Naji LH, Badrani JH, Mehta A, Croft M, Broide DH, Doherty TA.

J Immunol. 2017 Aug 1;199(3):1096-1104. doi: 10.4049/jimmunol.1601569. Epub 2017 Jun 30.

PMID:
28667163
13.

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages.

Molofsky AB, Nussbaum JC, Liang HE, Van Dyken SJ, Cheng LE, Mohapatra A, Chawla A, Locksley RM.

J Exp Med. 2013 Mar 11;210(3):535-49. doi: 10.1084/jem.20121964. Epub 2013 Feb 18.

14.

Group 2 innate lymphoid cell production of IL-5 is regulated by NKT cells during influenza virus infection.

Gorski SA, Hahn YS, Braciale TJ.

PLoS Pathog. 2013 Sep;9(9):e1003615. doi: 10.1371/journal.ppat.1003615. Epub 2013 Sep 19.

15.

Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells.

Klein Wolterink RG, Serafini N, van Nimwegen M, Vosshenrich CA, de Bruijn MJ, Fonseca Pereira D, Veiga Fernandes H, Hendriks RW, Di Santo JP.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10240-5. doi: 10.1073/pnas.1217158110. Epub 2013 Jun 3.

16.

Chronic intestinal nematode infection induces Stat6-independent interleukin-5 production and causes eosinophilic inflammatory responses in mice.

Sakamoto Y, Hiromatsu K, Ishiwata K, Inagaki-Ohara K, Ikeda T, Nakamura-Uchiyama F, Nawa Y.

Immunology. 2004 Aug;112(4):615-23.

17.

The roles of eotaxin and the STAT6 signalling pathway in eosinophil recruitment and host resistance to the nematodes Nippostrongylus brasiliensis and Heligmosomoides bakeri.

Knott ML, Matthaei KI, Foster PS, Dent LA.

Mol Immunol. 2009 Aug;46(13):2714-22. doi: 10.1016/j.molimm.2009.05.016. Epub 2009 Jun 16.

PMID:
19535141
18.

Nippostrongylus brasiliensis: identification of intelectin-1 and -2 as Stat6-dependent genes expressed in lung and intestine during infection.

Voehringer D, Stanley SA, Cox JS, Completo GC, Lowary TL, Locksley RM.

Exp Parasitol. 2007 Aug;116(4):458-66. Epub 2007 Mar 6.

19.

T-bet inhibits innate lymphoid cell-mediated eosinophilic airway inflammation by suppressing IL-9 production.

Matsuki A, Takatori H, Makita S, Yokota M, Tamachi T, Suto A, Suzuki K, Hirose K, Nakajima H.

J Allergy Clin Immunol. 2017 Apr;139(4):1355-1367.e6. doi: 10.1016/j.jaci.2016.08.022. Epub 2016 Sep 23.

PMID:
27670243
20.

Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris.

Bowcutt R, Bell LV, Little M, Wilson J, Booth C, Murray PJ, Else KJ, Cruickshank SM.

Parasite Immunol. 2011 Jul;33(7):411-20. doi: 10.1111/j.1365-3024.2011.01300.x.

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