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Items: 1 to 20 of 135

1.

Enhancer of zeste homolog 2 is a negative regulator of mitochondria-mediated innate immune responses.

Chen S, Sheng C, Liu D, Yao C, Gao S, Song L, Jiang W, Li J, Huang W.

J Immunol. 2013 Sep 1;191(5):2614-23. doi: 10.4049/jimmunol.1203143. Epub 2013 Aug 5.

2.

Scaffolding adaptor protein Gab1 is required for TLR3/4- and RIG-I-mediated production of proinflammatory cytokines and type I IFN in macrophages.

Zheng Y, An H, Yao M, Hou J, Yu Y, Feng G, Cao X.

J Immunol. 2010 Jun 1;184(11):6447-56. doi: 10.4049/jimmunol.0901750. Epub 2010 Apr 30.

3.

Phosphatidylinositol-3-kinase and Akt are required for RIG-I-mediated anti-viral signalling through cross-talk with IPS-1.

Yeon SH, Song MJ, Kang HR, Lee JY.

Immunology. 2015 Feb;144(2):312-20. doi: 10.1111/imm.12373.

4.

ECSIT bridges RIG-I-like receptors to VISA in signaling events of innate antiviral responses.

Lei CQ, Zhang Y, Li M, Jiang LQ, Zhong B, Kim YH, Shu HB.

J Innate Immun. 2015;7(2):153-64. doi: 10.1159/000365971. Epub 2014 Sep 16.

PMID:
25228397
5.

SOCS3 Drives Proteasomal Degradation of TBK1 and Negatively Regulates Antiviral Innate Immunity.

Liu D, Sheng C, Gao S, Yao C, Li J, Jiang W, Chen H, Wu J, Pan C, Chen S, Huang W.

Mol Cell Biol. 2015 Jul;35(14):2400-13. doi: 10.1128/MCB.00090-15. Epub 2015 May 4.

6.

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.

Wies E, Wang MK, Maharaj NP, Chen K, Zhou S, Finberg RW, Gack MU.

Immunity. 2013 Mar 21;38(3):437-49. doi: 10.1016/j.immuni.2012.11.018. Epub 2013 Mar 14.

7.

TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1.

Lee Y, Song B, Park C, Kwon KS.

PLoS One. 2013 May 13;8(5):e63255. doi: 10.1371/journal.pone.0063255. Print 2013.

8.

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential.

Oshiumi H, Sakai K, Matsumoto M, Seya T.

Eur J Immunol. 2010 Apr;40(4):940-8. doi: 10.1002/eji.200940203.

9.

Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity.

Onomoto K, Jogi M, Yoo JS, Narita R, Morimoto S, Takemura A, Sambhara S, Kawaguchi A, Osari S, Nagata K, Matsumiya T, Namiki H, Yoneyama M, Fujita T.

PLoS One. 2012;7(8):e43031. doi: 10.1371/journal.pone.0043031. Epub 2012 Aug 13. Erratum in: PLoS One. 2013;8(4). doi:10.1371/annotation/14a6b875-ed9d-41ae-8ce6-52e8c5c7f85b. PLoS One. 2012;7(10). doi:10.1371/annotation/dcd836ee-9e23-4538-acb7-450560ba5c1d.

10.

The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein.

Wei C, Ni C, Song T, Liu Y, Yang X, Zheng Z, Jia Y, Yuan Y, Guan K, Xu Y, Cheng X, Zhang Y, Yang X, Wang Y, Wen C, Wu Q, Shi W, Zhong H.

J Immunol. 2010 Jul 15;185(2):1158-68. doi: 10.4049/jimmunol.0903874. Epub 2010 Jun 16.

11.

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways.

Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP.

Immunity. 2011 Jun 24;34(6):854-65. doi: 10.1016/j.immuni.2011.03.026.

12.

β-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling.

Hillesheim A, Nordhoff C, Boergeling Y, Ludwig S, Wixler V.

Cell Commun Signal. 2014 Apr 26;12:29. doi: 10.1186/1478-811X-12-29.

13.

The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.

Ma H, Han P, Ye W, Chen H, Zheng X, Cheng L, Zhang L, Yu L, Wu X, Xu Z, Lei Y, Zhang F.

J Virol. 2017 Apr 13;91(9). pii: e02250-16. doi: 10.1128/JVI.02250-16. Print 2017 May 1.

14.

EZH2 expands breast stem cells through activation of NOTCH1 signaling.

Gonzalez ME, Moore HM, Li X, Toy KA, Huang W, Sabel MS, Kidwell KM, Kleer CG.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3098-103. doi: 10.1073/pnas.1308953111. Epub 2014 Feb 10.

15.

Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells.

Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM.

PLoS Pathog. 2013;9(4):e1003256. doi: 10.1371/journal.ppat.1003256. Epub 2013 Apr 11.

17.

A Src-family-tyrosine kinase, Lyn, is required for efficient IFN-β expression in pattern recognition receptor, RIG-I, signal pathway by interacting with IPS-1.

Lim YJ, Koo JE, Hong EH, Park ZY, Lim KM, Bae ON, Lee JY.

Cytokine. 2015 Mar;72(1):63-70. doi: 10.1016/j.cyto.2014.12.008. Epub 2015 Jan 10.

PMID:
25585356
18.

Regulation of RLR-mediated innate immune signaling--it is all about keeping the balance.

Eisenächer K, Krug A.

Eur J Cell Biol. 2012 Jan;91(1):36-47. doi: 10.1016/j.ejcb.2011.01.011. Epub 2011 Apr 9. Review.

PMID:
21481967
19.

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction.

Gack MU, Kirchhofer A, Shin YC, Inn KS, Liang C, Cui S, Myong S, Ha T, Hopfner KP, Jung JU.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16743-8. doi: 10.1073/pnas.0804947105. Epub 2008 Oct 23.

20.

Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I.

Pang IK, Pillai PS, Iwasaki A.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13910-5. doi: 10.1073/pnas.1303275110. Epub 2013 Aug 5.

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