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Items: 1 to 20 of 109

1.

Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.

Pauls E, Nanda SK, Smith H, Toth R, Arthur JSC, Cohen P.

J Immunol. 2013 Sep 1;191(5):2717-30. doi: 10.4049/jimmunol.1203268. Epub 2013 Aug 5. Erratum in: J Immunol. 2013 Nov 15;191(10):5317.

3.

The dual functions of IL-1 receptor-associated kinase 2 in TLR9-mediated IFN and proinflammatory cytokine production.

Wan Y, Kim TW, Yu M, Zhou H, Yamashita M, Kang Z, Yin W, Wang JA, Thomas J, Sen GC, Stark GR, Li X.

J Immunol. 2011 Mar 1;186(5):3006-14. doi: 10.4049/jimmunol.1003217. Epub 2011 Jan 26.

4.

Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance.

Murphy M, Xiong Y, Pattabiraman G, Qiu F, Medvedev AE.

J Biol Chem. 2015 Jul 31;290(31):19218-32. doi: 10.1074/jbc.M115.640128. Epub 2015 Jun 16.

5.

The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation.

Ma J, Bang BR, Lu J, Eun SY, Otsuka M, Croft M, Tobias P, Han J, Takeuchi O, Akira S, Karin M, Yagita H, Kang YJ.

Sci Signal. 2013 Oct 1;6(295):ra87. doi: 10.1126/scisignal.2004431.

7.

Toll-like receptors and their adaptors are regulated in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles.

Hirayama T, Tamaki Y, Takakubo Y, Iwazaki K, Sasaki K, Ogino T, Goodman SB, Konttinen YT, Takagi M.

J Orthop Res. 2011 Jul;29(7):984-92. doi: 10.1002/jor.21369. Epub 2011 Feb 9.

8.

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Saitoh T, Kawai T, Takeuchi O, Akira S.

Nat Immunol. 2008 Jun;9(6):684-91. doi: 10.1038/ni.1606. Epub 2008 Apr 27.

PMID:
18438411
9.

Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control.

Wan Y, Xiao H, Affolter J, Kim TW, Bulek K, Chaudhuri S, Carlson D, Hamilton T, Mazumder B, Stark GR, Thomas J, Li X.

J Biol Chem. 2009 Apr 17;284(16):10367-75. doi: 10.1074/jbc.M807822200. Epub 2009 Feb 18.

10.

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction.

Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S.

J Exp Med. 2005 Mar 21;201(6):915-23. Epub 2005 Mar 14.

11.

MicroRNA-146a and microRNA-146b regulate human dendritic cell apoptosis and cytokine production by targeting TRAF6 and IRAK1 proteins.

Park H, Huang X, Lu C, Cairo MS, Zhou X.

J Biol Chem. 2015 Jan 30;290(5):2831-41. doi: 10.1074/jbc.M114.591420. Epub 2014 Dec 11.

13.

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity.

Kim TW, Staschke K, Bulek K, Yao J, Peters K, Oh KH, Vandenburg Y, Xiao H, Qian W, Hamilton T, Min B, Sen G, Gilmour R, Li X.

J Exp Med. 2007 May 14;204(5):1025-36. Epub 2007 Apr 30.

14.

Morphine inhibits murine dendritic cell IL-23 production by modulating Toll-like receptor 2 and Nod2 signaling.

Wang J, Ma J, Charboneau R, Barke R, Roy S.

J Biol Chem. 2011 Mar 25;286(12):10225-32. doi: 10.1074/jbc.M110.188680. Epub 2011 Jan 18.

15.

The kinase activity of interleukin-1 receptor-associated kinase 2 is essential for lipopolysaccharide-mediated cytokine and chemokine mRNA stability and translation.

Yin W, Wan Y, Kim TW, Yao P, Xiao H, Zhou H, Xiao J, Fox P, Li X.

J Interferon Cytokine Res. 2011 May;31(5):415-22. doi: 10.1089/jir.2010.0094. Epub 2011 Feb 3.

16.

An anti-interferon activity shared by paramyxovirus C proteins: inhibition of Toll-like receptor 7/9-dependent alpha interferon induction.

Yamaguchi M, Kitagawa Y, Zhou M, Itoh M, Gotoh B.

FEBS Lett. 2014 Jan 3;588(1):28-34. doi: 10.1016/j.febslet.2013.11.015. Epub 2013 Nov 20.

17.

TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9.

Liu YC, Simmons DP, Li X, Abbott DW, Boom WH, Harding CV.

J Immunol. 2012 Feb 1;188(3):1019-26. doi: 10.4049/jimmunol.1102181. Epub 2012 Jan 6.

18.

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

Gotoh K, Tanaka Y, Nishikimi A, Nakamura R, Yamada H, Maeda N, Ishikawa T, Hoshino K, Uruno T, Cao Q, Higashi S, Kawaguchi Y, Enjoji M, Takayanagi R, Kaisho T, Yoshikai Y, Fukui Y.

J Exp Med. 2010 Apr 12;207(4):721-30. doi: 10.1084/jem.20091776. Epub 2010 Mar 15.

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