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Items: 1 to 20 of 106

1.

Requirement and redundancy of the Src family kinases Fyn and Lyn in perforin-dependent killing of Cryptococcus neoformans by NK cells.

Oykhman P, Timm-McCann M, Xiang RF, Islam A, Li SS, Stack D, Huston SM, Ma LL, Mody CH.

Infect Immun. 2013 Oct;81(10):3912-22. doi: 10.1128/IAI.00533-13. Epub 2013 Aug 5.

2.

Perforin-dependent cryptococcal microbicidal activity in NK cells requires PI3K-dependent ERK1/2 signaling.

Wiseman JC, Ma LL, Marr KJ, Jones GJ, Mody CH.

J Immunol. 2007 May 15;178(10):6456-64.

3.

An acidic microenvironment increases NK cell killing of Cryptococcus neoformans and Cryptococcus gattii by enhancing perforin degranulation.

Islam A, Li SS, Oykhman P, Timm-McCann M, Huston SM, Stack D, Xiang RF, Kelly MM, Mody CH.

PLoS Pathog. 2013;9(7):e1003439. doi: 10.1371/journal.ppat.1003439. Epub 2013 Jul 11.

4.
5.

Mechanisms by Which Interleukin-12 Corrects Defective NK Cell Anticryptococcal Activity in HIV-Infected Patients.

Kyei SK, Ogbomo H, Li S, Timm-McCann M, Xiang RF, Huston SM, Ganguly A, Colarusso P, Gill MJ, Mody CH.

MBio. 2016 Aug 23;7(4). pii: e00878-16. doi: 10.1128/mBio.00878-16.

6.

Cryptococcus neoformans directly stimulates perforin production and rearms NK cells for enhanced anticryptococcal microbicidal activity.

Marr KJ, Jones GJ, Zheng C, Huston SM, Timm-McCann M, Islam A, Berenger BM, Ma LL, Wiseman JC, Mody CH.

Infect Immun. 2009 Jun;77(6):2436-46. doi: 10.1128/IAI.01232-08. Epub 2009 Mar 23.

7.

In contrast to anti-tumor activity, YT cell and primary NK cell cytotoxicity for Cryptococcus neoformans bypasses LFA-1.

Jones GJ, Wiseman JC, Marr KJ, Wei S, Djeu JY, Mody CH.

Int Immunol. 2009 Apr;21(4):423-32. doi: 10.1093/intimm/dxp010. Epub 2009 Mar 4.

PMID:
19261694
8.

Regulation of Ly49D/DAP12 signal transduction by Src-family kinases and CD45.

Mason LH, Willette-Brown J, Taylor LS, McVicar DW.

J Immunol. 2006 Jun 1;176(11):6615-23.

9.

Deficiency of Fyn protein is prerequisite for apoptosis induced by Src family kinase inhibitors in human mesothelioma cells.

Eguchi R, Kubo S, Takeda H, Ohta T, Tabata C, Ogawa H, Nakano T, Fujimori Y.

Carcinogenesis. 2012 May;33(5):969-75. doi: 10.1093/carcin/bgs109. Epub 2012 Feb 21.

PMID:
22354875
10.

NK cells use perforin rather than granulysin for anticryptococcal activity.

Ma LL, Wang CL, Neely GG, Epelman S, Krensky AM, Mody CH.

J Immunol. 2004 Sep 1;173(5):3357-65.

11.
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13.

Beta1 integrin-mediated activation of focal adhesion kinase and its association with Fyn and Zap-70 in human NK cells.

Rabinowich H, Manciulea M, Herberman RB, Whiteside TL.

J Immunol. 1996 Nov 1;157(9):3860-8.

PMID:
8892616
14.

Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration.

Yadav V, Denning MF.

Mol Carcinog. 2011 May;50(5):346-52. doi: 10.1002/mc.20716. Epub 2010 Dec 10.

15.

Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida.

Li SS, Ogbomo H, Mansour MK, Xiang RF, Szabo L, Munro F, Mukherjee P, Mariuzza RA, Amrein M, Vyas JM, Robbins SM, Mody CH.

Nat Commun. 2018 Feb 21;9(1):751. doi: 10.1038/s41467-018-03014-4.

16.

β1 Integrins Are Required To Mediate NK Cell Killing of Cryptococcus neoformans.

Xiang RF, Li S, Ogbomo H, Stack D, Mody CH.

J Immunol. 2018 Oct 15;201(8):2369-2376. doi: 10.4049/jimmunol.1701805. Epub 2018 Sep 10.

PMID:
30201811
17.

Oligodendrocyte differentiation and signaling after transferrin internalization: a mechanism of action.

Pérez MJ, Fernandez N, Pasquini JM.

Exp Neurol. 2013 Oct;248:262-74. doi: 10.1016/j.expneurol.2013.06.014. Epub 2013 Jun 21.

PMID:
23797152
18.

The inhibition of SRC family kinase suppresses pancreatic cancer cell proliferation, migration, and invasion.

Je DW, O YM, Ji YG, Cho Y, Lee DH.

Pancreas. 2014 Jul;43(5):768-76. doi: 10.1097/MPA.0000000000000103.

PMID:
24763074
20.

Rapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling.

James AM, Hsu HT, Dongre P, Uzel G, Mace EM, Banerjee PP, Orange JS.

Blood. 2013 Apr 4;121(14):2627-37. doi: 10.1182/blood-2012-06-437012. Epub 2013 Feb 4.

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