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Items: 1 to 20 of 60

1.

SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma.

Ren F, Su F, Ning H, Wang Y, Geng Y, Feng Y, Wang Y, Zhang Y, Jin Z, Li Y, Jia B, Chang Z.

Cell Signal. 2013 Nov;25(11):2272-80. doi: 10.1016/j.cellsig.2013.07.023. Epub 2013 Jul 31.

PMID:
23917203
2.

Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.

Ren F, Geng Y, Minami T, Qiu Y, Feng Y, Liu C, Zhao J, Wang Y, Fan X, Wang Y, Li M, Li J, Chang Z.

FEBS Lett. 2015 Jul 8;589(15):1890-6. doi: 10.1016/j.febslet.2015.05.031. Epub 2015 May 27.

3.

Stat3 inhibits WTX expression through up-regulation of microRNA-370 in Wilms tumor.

Cao X, Liu D, Yan X, Zhang Y, Yuan L, Zhang T, Fu M, Zhou Y, Wang J.

FEBS Lett. 2013 Mar 18;587(6):639-44. doi: 10.1016/j.febslet.2013.01.012. Epub 2013 Jan 17.

4.

Downregulation of Stat3 in melanoma: reprogramming the immune microenvironment as an anticancer therapeutic strategy.

Emeagi PU, Maenhout S, Dang N, Heirman C, Thielemans K, Breckpot K.

Gene Ther. 2013 Nov;20(11):1085-92. doi: 10.1038/gt.2013.35. Epub 2013 Jun 27.

PMID:
23804077
5.

Signal transducer and activator of transcription 3 upregulates interleukin-8 expression at the level of transcription in human melanoma cells.

Oka M, Sakaguchi M, Okada T, Nagai H, Ozaki M, Yoshioka T, Inoue H, Mukaida N, Kikkawa U, Nishigori C.

Exp Dermatol. 2010 Aug;19(8):e50-5. doi: 10.1111/j.1600-0625.2009.00972.x.

6.

Protein tyrosine phosphatase Meg2 dephosphorylates signal transducer and activator of transcription 3 and suppresses tumor growth in breast cancer.

Su F, Ren F, Rong Y, Wang Y, Geng Y, Wang Y, Feng M, Ju Y, Li Y, Zhao ZJ, Meng K, Chang Z.

Breast Cancer Res. 2012 Mar 6;14(2):R38.

7.

The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation.

Yamamoto T, Sekine Y, Kashima K, Kubota A, Sato N, Aoki N, Matsuda T.

Biochem Biophys Res Commun. 2002 Oct 4;297(4):811-7.

PMID:
12359225
8.

Quercetin exerts anti-melanoma activities and inhibits STAT3 signaling.

Cao HH, Tse AK, Kwan HY, Yu H, Cheng CY, Su T, Fong WF, Yu ZL.

Biochem Pharmacol. 2014 Feb 1;87(3):424-34. doi: 10.1016/j.bcp.2013.11.008. Epub 2013 Nov 23.

PMID:
24275163
9.

ECHS1 interacts with STAT3 and negatively regulates STAT3 signaling.

Chang Y, Wang SX, Wang YB, Zhou J, Li WH, Wang N, Fang DF, Li HY, Li AL, Zhang XM, Zhang WN.

FEBS Lett. 2013 Mar 18;587(6):607-13. doi: 10.1016/j.febslet.2013.02.005. Epub 2013 Feb 14.

10.

Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells.

Zhang Y, Du XL, Wang CJ, Lin DC, Ruan X, Feng YB, Huo YQ, Peng H, Cui JL, Zhang TT, Wang YQ, Zhang H, Zhan QM, Wang MR.

Gastroenterology. 2012 Mar;142(3):521-530.e3. doi: 10.1053/j.gastro.2011.11.023. Epub 2011 Nov 19.

PMID:
22108192
11.

Activated signal transducers and activators of transcription 3 signaling induces CD46 expression and protects human cancer cells from complement-dependent cytotoxicity.

Buettner R, Huang M, Gritsko T, Karras J, Enkemann S, Mesa T, Nam S, Yu H, Jove R.

Mol Cancer Res. 2007 Aug;5(8):823-32.

12.

[Effects of STAT3 antisense oligodeoxynucleotides on apoptosis and proliferation of mouse melanoma cell line B16].

Tang GS, Cai JM, Ni J, Xiang YS, Cui JG, Zhu D, Dong JR.

Ai Zheng. 2006 Mar;25(3):269-74. Chinese.

PMID:
16536977
13.

Pentoxifylline inhibits melanoma tumor growth and angiogenesis by targeting STAT3 signaling pathway.

Kamran MZ, Gude RP.

Biomed Pharmacother. 2013 Jun;67(5):399-405. doi: 10.1016/j.biopha.2013.03.020. Epub 2013 Apr 17.

PMID:
23639230
14.

Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis.

Yang F, Jove V, Buettner R, Xin H, Wu J, Wang Y, Nam S, Xu Y, Ara T, DeClerck YA, Seeger R, Yu H, Jove R.

Cancer Biol Ther. 2012 May;13(7):534-41. doi: 10.4161/cbt.19603. Epub 2012 May 1.

PMID:
22406995
15.

Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases.

Kreis S, Munz GA, Haan S, Heinrich PC, Behrmann I.

Mol Cancer Res. 2007 Dec;5(12):1331-41. doi: 10.1158/1541-7786.MCR-07-0317.

17.

Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway.

Yang F, Zhang W, Li D, Zhan Q.

J Biol Chem. 2013 Mar 1;288(9):6552-60. doi: 10.1074/jbc.M112.418335. Epub 2013 Jan 17.

18.

A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling.

Liu L, Kritsanida M, Magiatis P, Gaboriaud N, Wang Y, Wu J, Buettner R, Yang F, Nam S, Skaltsounis L, Jove R.

Cancer Biol Ther. 2012 Nov;13(13):1255-61. doi: 10.4161/cbt.21781. Epub 2012 Aug 16.

19.

Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo.

Labelle-Côté M, Dusseault J, Ismaïl S, Picard-Cloutier A, Siegel PM, Larose L.

BMC Cancer. 2011 Oct 12;11:443. doi: 10.1186/1471-2407-11-443.

20.

Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cells.

Zhang G, Tsang CM, Deng W, Yip YL, Lui VW, Wong SC, Cheung AL, Hau PM, Zeng M, Lung ML, Chen H, Lo KW, Takada K, Tsao SW.

PLoS One. 2013 May 1;8(5):e62284. doi: 10.1371/journal.pone.0062284. Print 2013.

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