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Items: 1 to 20 of 173

1.

In vivo activating transcription factor 3 silencing ameliorates the AMPK compensatory effects for ER stress-mediated β-cell dysfunction during the progression of type-2 diabetes.

Kim JY, Park KJ, Kim GH, Jeong EA, Lee DY, Lee SS, Kim DJ, Roh GS, Song J, Ki SH, Kim WH.

Cell Signal. 2013 Dec;25(12):2348-61. doi: 10.1016/j.cellsig.2013.07.028. Epub 2013 Aug 2.

PMID:
23916985
2.

The induction of STAT1 gene by activating transcription factor 3 contributes to pancreatic beta-cell apoptosis and its dysfunction in streptozotocin-treated mice.

Kim JY, Song EH, Lee S, Lim JH, Choi JS, Koh IU, Song J, Kim WH.

Cell Signal. 2010 Nov;22(11):1669-80. doi: 10.1016/j.cellsig.2010.06.007. Epub 2010 Jun 26.

PMID:
20600850
3.

Chronic ethanol consumption inhibits glucokinase transcriptional activity by Atf3 and triggers metabolic syndrome in vivo.

Kim JY, Hwang JY, Lee DY, Song EH, Park KJ, Kim GH, Jeong EA, Lee YJ, Go MJ, Kim DJ, Lee SS, Kim BJ, Song J, Roh GS, Gao B, Kim WH.

J Biol Chem. 2014 Sep 26;289(39):27065-79. doi: 10.1074/jbc.M114.585653. Epub 2014 Jul 29.

4.

Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.

Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, Takai T, Suzuki E, Kanno A, Koyanagi-Kimura M, Asahara S, Bartolome A, Yokoi N, Inoue H, Ogawa W, Seino S, Kido Y.

PLoS One. 2015 Jun 19;10(6):e0130757. doi: 10.1371/journal.pone.0130757. eCollection 2015.

5.

ER stress is implicated in mitochondrial dysfunction-induced apoptosis of pancreatic beta cells.

Lee JW, Kim WH, Yeo J, Jung MH.

Mol Cells. 2010 Dec;30(6):545-9. doi: 10.1007/s10059-010-0161-5. Epub 2010 Dec 3.

6.

Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6.

Green CD, Olson LK.

Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E640-9. doi: 10.1152/ajpendo.00544.2010. Epub 2011 Jan 25.

7.

JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis.

Prause M, Christensen DP, Billestrup N, Mandrup-Poulsen T.

PLoS One. 2014 Jan 24;9(1):e87067. doi: 10.1371/journal.pone.0087067. eCollection 2014.

8.

Compound K protects pancreatic islet cells against apoptosis through inhibition of the AMPK/JNK pathway in type 2 diabetic mice and in MIN6 β-cells.

Guan FY, Gu J, Li W, Zhang M, Ji Y, Li J, Chen L, Hatch GM.

Life Sci. 2014 Jun 27;107(1-2):42-9. doi: 10.1016/j.lfs.2014.04.034. Epub 2014 May 5.

PMID:
24802125
9.

The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction.

Zmuda EJ, Qi L, Zhu MX, Mirmira RG, Montminy MR, Hai T.

Mol Endocrinol. 2010 Jul;24(7):1423-33. doi: 10.1210/me.2009-0463. Epub 2010 Jun 2.

10.
11.

Inhibitory cross-talk between the AMPK and ERK pathways mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle.

Hwang SL, Jeong YT, Li X, Kim YD, Lu Y, Chang YC, Lee IK, Chang HW.

Br J Pharmacol. 2013 May;169(1):69-81. doi: 10.1111/bph.12124.

12.

Thioredoxin-mimetic peptide CB3 lowers MAPKinase activity in the Zucker rat brain.

Cohen-Kutner M, Khomsky L, Trus M, Ben-Yehuda H, Lenhard JM, Liang Y, Martin T, Atlas D.

Redox Biol. 2014 Jan 9;2:447-56. doi: 10.1016/j.redox.2013.12.018. eCollection 2014.

13.

AMPK regulates ER morphology and function in stressed pancreatic β-cells via phosphorylation of DRP1.

Wikstrom JD, Israeli T, Bachar-Wikstrom E, Swisa A, Ariav Y, Waiss M, Kaganovich D, Dor Y, Cerasi E, Leibowitz G.

Mol Endocrinol. 2013 Oct;27(10):1706-23. doi: 10.1210/me.2013-1109. Epub 2013 Aug 26.

PMID:
23979843
14.

Activating Transcription Factor 3 Is a Target Molecule Linking Hepatic Steatosis to Impaired Glucose Homeostasis.

Kim JY, Park KJ, Hwang JY, Kim GH, Lee D, Lee YJ, Song EH, Yoo MG, Kim BJ, Suh YH, Roh GS, Gao B, Kim W, Kim WH.

J Hepatol. 2017 Mar 30. pii: S0168-8278(17)30187-3. doi: 10.1016/j.jhep.2017.03.023. [Epub ahead of print]

15.

Low molecular weight fucoidan improves endoplasmic reticulum stress-reduced insulin sensitivity through AMP-activated protein kinase activation in L6 myotubes and restores lipid homeostasis in a mouse model of type 2 diabetes.

Jeong YT, Kim YD, Jung YM, Park DC, Lee DS, Ku SK, Li X, Lu Y, Chao GH, Kim KJ, Lee JY, Baek MC, Kang W, Hwang SL, Chang HW.

Mol Pharmacol. 2013 Jul;84(1):147-57. doi: 10.1124/mol.113.085100. Epub 2013 May 8.

16.

Voluntary running exercise prevents β-cell failure in susceptible islets of the Zucker diabetic fatty rat.

Delghingaro-Augusto V, Décary S, Peyot ML, Latour MG, Lamontagne J, Paradis-Isler N, Lacharité-Lemieux M, Akakpo H, Birot O, Nolan CJ, Prentki M, Bergeron R.

Am J Physiol Endocrinol Metab. 2012 Jan 15;302(2):E254-64. doi: 10.1152/ajpendo.00360.2011. Epub 2011 Nov 1.

17.

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.

Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ.

Diabetologia. 2007 Apr;50(4):752-63. Epub 2007 Feb 1.

PMID:
17268797
18.

Metformin prevents endoplasmic reticulum stress-induced apoptosis through AMPK-PI3K-c-Jun NH2 pathway.

Jung TW, Lee MW, Lee YJ, Kim SM.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):147-52. doi: 10.1016/j.bbrc.2011.11.073. Epub 2011 Nov 23.

PMID:
22138650
19.

Long-term AICAR administration and exercise prevents diabetes in ZDF rats.

Pold R, Jensen LS, Jessen N, Buhl ES, Schmitz O, Flyvbjerg A, Fujii N, Goodyear LJ, Gotfredsen CF, Brand CL, Lund S.

Diabetes. 2005 Apr;54(4):928-34.

20.

Activating transcription factor 3-mediated chemo-intervention with cancer chemokines in a noncanonical pathway under endoplasmic reticulum stress.

Park SH, Kim J, Do KH, Park J, Oh CG, Choi HJ, Song BG, Lee SJ, Kim YS, Moon Y.

J Biol Chem. 2014 Sep 26;289(39):27118-33. doi: 10.1074/jbc.M114.568717. Epub 2014 Aug 13.

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