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Expression of Membrane Complement Regulatory Proteins Crry and CD55 in Normal Rats.

Kato C, Kato A, Adachi K, Fujii E, Isobe K, Watanabe T, Ito T, Suzuki M.

J Toxicol Pathol. 2013 Jun;26(2):223-6. doi: 10.1293/tox.26.223. Epub 2013 Jul 10.


Anti-Thy-1 Antibody-mediated Complement-dependent Cytotoxicity is Regulated by the Distribution of Antigen, Antibody and Membrane Complement Regulatory Proteins in Rats.

Kato C, Kato A, Adachi K, Fujii E, Isobe K, Matsushita T, Watanabe T, Suzuki M.

J Toxicol Pathol. 2013 Mar;26(1):41-9. doi: 10.1293/tox.26.41. Epub 2013 Apr 22.


Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy.

Bellone S, Roque D, Cocco E, Gasparrini S, Bortolomai I, Buza N, Abu-Khalaf M, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD.

Br J Cancer. 2012 Apr 24;106(9):1543-50. doi: 10.1038/bjc.2012.132.


Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.

Kim YU, Kinoshita T, Molina H, Hourcade D, Seya T, Wagner LM, Holers VM.

J Exp Med. 1995 Jan 1;181(1):151-9.


Chronic low level complement activation within the eye is controlled by intraocular complement regulatory proteins.

Sohn JH, Kaplan HJ, Suk HJ, Bora PS, Bora NS.

Invest Ophthalmol Vis Sci. 2000 Oct;41(11):3492-502.


Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg.

Kim DD, Miwa T, Kimura Y, Schwendener RA, van Lookeren Campagne M, Song WC.

Blood. 2008 Aug 15;112(4):1109-19. doi: 10.1182/blood-2008-01-134304. Epub 2008 Jun 4.


Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor.

Molina H, Miwa T, Zhou L, Hilliard B, Mastellos D, Maldonado MA, Lambris JD, Song WC.

Blood. 2002 Dec 15;100(13):4544-9. Epub 2002 Aug 1.


Rat T cells express neither CD55 nor CD59 and are dependent on Crry for protection from homologous complement.

Hanna S, Spiller O, Linton SM, Mead RJ, Morgan B.

Eur J Immunol. 2002 Feb;32(2):502-9.


Neutralization of membrane complement regulators improves complement-dependent effector functions of therapeutic anticancer antibodies targeting leukemic cells.

Mamidi S, Höne S, Teufel C, Sellner L, Zenz T, Kirschfink M.

Oncoimmunology. 2015 Jan 22;4(3):e979688. eCollection 2015 Mar.


Membrane-bound complement regulatory proteins are prognostic factors of operable breast cancer treated with adjuvant trastuzumab: a retrospective study.

Liu M, Yang YJ, Zheng H, Zhong XR, Wang Y, Wang Z, Wang YG, Wang YP.

Oncol Rep. 2014 Dec;32(6):2619-27. doi: 10.3892/or.2014.3496. Epub 2014 Sep 18.


Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors.

Fishelson Z, Donin N, Zell S, Schultz S, Kirschfink M.

Mol Immunol. 2003 Sep;40(2-4):109-23. Review.


Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF.

Li B, Sallee C, Dehoff M, Foley S, Molina H, Holers VM.

J Immunol. 1993 Oct 15;151(8):4295-305.


Complement activation cascade and its regulation: relevance for the response of solid tumors to photodynamic therapy.

Korbelik M, Cecic I.

J Photochem Photobiol B. 2008 Oct 16;93(1):53-9. doi: 10.1016/j.jphotobiol.2008.04.005. Epub 2008 Apr 26.


DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity.

Miwa T, Zhou L, Tudoran R, Lambris JD, Madaio MP, Nangaku M, Molina H, Song WC.

Mol Immunol. 2007 Jan;44(1-3):139-46. Epub 2006 Aug 2.


Down-regulation of CD55 and CD46 expression by anti-sense phosphorothioate oligonucleotides (S-ODNs) sensitizes tumour cells to complement attack.

Zell S, Geis N, Rutz R, Schultz S, Giese T, Kirschfink M.

Clin Exp Immunol. 2007 Dec;150(3):576-84. Epub 2007 Sep 28.


Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells.

Quigg RJ, Morgan BP, Holers VM, Adler S, Sneed AE 3rd, Lo CF.

Kidney Int. 1995 Aug;48(2):412-21.


Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells.

Fernández-Centeno E, de Ojeda G, Rojo JM, Portolés P.

J Immunol. 2000 May 1;164(9):4533-42.


Deletion of Crry and DAF on murine platelets stimulates thrombopoiesis and increases factor H-dependent resistance of peripheral platelets to complement attack.

Barata L, Miwa T, Sato S, Kim D, Mohammed I, Song WC.

J Immunol. 2013 Mar 15;190(6):2886-95. doi: 10.4049/jimmunol.1202536. Epub 2013 Feb 6.

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