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Items: 1 to 20 of 117


Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy.

Chen J, Michan S, Juan AM, Hurst CG, Hatton CJ, Pei DT, Joyal JS, Evans LP, Cui Z, Stahl A, Sapieha P, Sinclair DA, Smith LE.

Angiogenesis. 2013 Oct;16(4):985-92. doi: 10.1007/s10456-013-9374-5. Epub 2013 Aug 4.


Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy.

Michan S, Juan AM, Hurst CG, Cui Z, Evans LP, Hatton CJ, Pei DT, Ju M, Sinclair DA, Smith LE, Chen J.

PLoS One. 2014 Jan 8;9(1):e85031. doi: 10.1371/journal.pone.0085031. eCollection 2014.


Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A.

Wei Y, Gong J, Xu Z, Thimmulappa RK, Mitchell KL, Welsbie DS, Biswal S, Duh EJ.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6927-36. doi: 10.1073/pnas.1512683112. Epub 2015 Nov 30.


Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A.

Joyal JS, Sitaras N, Binet F, Rivera JC, Stahl A, Zaniolo K, Shao Z, Polosa A, Zhu T, Hamel D, Djavari M, Kunik D, Honoré JC, Picard E, Zabeida A, Varma DR, Hickson G, Mancini J, Klagsbrun M, Costantino S, Beauséjour C, Lachapelle P, Smith LE, Chemtob S, Sapieha P.

Blood. 2011 Jun 2;117(22):6024-35. doi: 10.1182/blood-2010-10-311589. Epub 2011 Feb 25.


HIF-2alpha-haploinsufficient mice have blunted retinal neovascularization due to impaired expression of a proangiogenic gene battery.

Dioum EM, Clarke SL, Ding K, Repa JJ, Garcia JA.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2714-20. doi: 10.1167/iovs.07-1469. Epub 2008 Feb 15.


PGC-1α regulates normal and pathological angiogenesis in the retina.

Saint-Geniez M, Jiang A, Abend S, Liu L, Sweigard H, Connor KM, Arany Z.

Am J Pathol. 2013 Jan;182(1):255-65. doi: 10.1016/j.ajpath.2012.09.003. Epub 2012 Nov 7.


Genetic inactivation of the adenosine A2A receptor attenuates pathologic but not developmental angiogenesis in the mouse retina.

Liu XL, Zhou R, Pan QQ, Jia XL, Gao WN, Wu J, Lin J, Chen JF.

Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6625-32. doi: 10.1167/iovs.09-4900. Epub 2010 Jul 7.


Reduced retinal neovascularization, vascular permeability, and apoptosis in ischemic retinopathy in the absence of prolyl hydroxylase-1 due to the prevention of hyperoxia-induced vascular obliteration.

Huang H, Van de Veire S, Dalal M, Parlier R, Semba RD, Carmeliet P, Vinores SA.

Invest Ophthalmol Vis Sci. 2011 Sep 29;52(10):7565-73. doi: 10.1167/iovs.11-8002.


Aldose reductase deficiency reduced vascular changes in neonatal mouse retina in oxygen-induced retinopathy.

Fu ZJ, Li SY, Kociok N, Wong D, Chung SK, Lo AC.

Invest Ophthalmol Vis Sci. 2012 Aug 20;53(9):5698-712. doi: 10.1167/iovs.12-10122.


Oxygen-induced retinopathy: a model for vascular pathology in the retina.

Scott A, Fruttiger M.

Eye (Lond). 2010 Mar;24(3):416-21. doi: 10.1038/eye.2009.306. Epub 2009 Dec 11.


Protective and antioxidant effects of PPARα in the ischemic retina.

Moran E, Ding L, Wang Z, Cheng R, Chen Q, Moore R, Takahashi Y, Ma JX.

Invest Ophthalmol Vis Sci. 2014 May 13;55(7):4568-76. doi: 10.1167/iovs.13-13127.


Ischaemia-induced retinal neovascularisation and diabetic retinopathy in mice with conditional knockout of hypoxia-inducible factor-1 in retinal Müller cells.

Lin M, Chen Y, Jin J, Hu Y, Zhou KK, Zhu M, Le YZ, Ge J, Johnson RS, Ma JX.

Diabetologia. 2011 Jun;54(6):1554-66. doi: 10.1007/s00125-011-2081-0. Epub 2011 Mar 1.


Application of recombinant peroxisome proliferator-activated receptor-γ coactivator-1α mediates neovascularization in the retina.

Jiang J, Zhang L, Zhang L, Xia X.

Mol Med Rep. 2016 Feb;13(2):1311-9. doi: 10.3892/mmr.2015.4678. Epub 2015 Dec 11.


Pleiotropic effects of YC-1 selectively inhibit pathological retinal neovascularization and promote physiological revascularization in a mouse model of oxygen-induced retinopathy.

DeNiro M, Al-Halafi A, Al-Mohanna FH, Alsmadi O, Al-Mohanna FA.

Mol Pharmacol. 2010 Mar;77(3):348-67. doi: 10.1124/mol.109.061366. Epub 2009 Dec 14.


Retinal vascular repair and neovascularization are not dependent on CX3CR1 signaling in a model of ischemic retinopathy.

Zhao L, Ma W, Fariss RN, Wong WT.

Exp Eye Res. 2009 Jun;88(6):1004-13. doi: 10.1016/j.exer.2008.12.013. Epub 2009 Jan 7.


Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity.

Pierce EA, Foley ED, Smith LE.

Arch Ophthalmol. 1996 Oct;114(10):1219-28. Erratum in: Arch Ophthalmol 1997 Mar;115(3):427.


Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a.

Zaniolo K, Sapieha P, Shao Z, Stahl A, Zhu T, Tremblay S, Picard E, Madaan A, Blais M, Lachapelle P, Mancini J, Hardy P, Smith LE, Ong H, Chemtob S.

Invest Ophthalmol Vis Sci. 2011 Jul 23;52(8):5376-86. doi: 10.1167/iovs.10-7152.


Up-regulation of VEGF by retinoic acid during hyperoxia prevents retinal neovascularization and retinopathy.

Wang L, Shi P, Xu Z, Li J, Xie Y, Mitton K, Drenser K, Yan Q.

Invest Ophthalmol Vis Sci. 2014 May 27;55(7):4276-87. doi: 10.1167/iovs.14-14170.


Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina.

Weidemann A, Krohne TU, Aguilar E, Kurihara T, Takeda N, Dorrell MI, Simon MC, Haase VH, Friedlander M, Johnson RS.

Glia. 2010 Aug;58(10):1177-85. doi: 10.1002/glia.20997.


Quantification of vascular tortuosity as an early outcome measure in oxygen induced retinopathy (OIR).

Scott A, Powner MB, Fruttiger M.

Exp Eye Res. 2014 Mar;120:55-60. doi: 10.1016/j.exer.2013.12.020. Epub 2014 Jan 10.


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