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Items: 1 to 20 of 140

1.

PHII-7 inhibits cell growth and induces apoptosis in leukemia cell line K562 as well as its MDR- counterpart K562/A02 through producing reactive oxygen species.

Peng H, Yuan X, Shi R, Wei X, Ren S, Yan C, Ding Y, Lin Y, Fan D, Yang M, Zhang Y, Xiong D.

Eur J Pharmacol. 2013 Oct 15;718(1-3):459-68. doi: 10.1016/j.ejphar.2013.07.038. Epub 2013 Jul 30.

PMID:
23911883
2.

Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells.

Cai Y, Lu J, Miao Z, Lin L, Ding J.

Cancer Biol Ther. 2007 Nov;6(11):1794-9. Epub 2007 Aug 12.

PMID:
18032928
3.

A novel indirubin derivative PHII-7 potentiates adriamycin cytotoxicity via inhibiting P-glycoprotein expression in human breast cancer MCF-7/ADR cells.

Shi R, Li W, Zhang X, Zhang Y, Peng H, Xie Y, Fan D, Liu R, Liu X, Xiong D.

Eur J Pharmacol. 2011 Nov 1;669(1-3):38-44. doi: 10.1016/j.ejphar.2011.07.047. Epub 2011 Aug 19.

PMID:
21871878
4.

Aromatic heterocyclic esters of podophyllotoxin exert anti-MDR activity in human leukemia K562/ADR cells via ROS/MAPK signaling pathways.

Zhang L, Zhang Z, Chen F, Chen Y, Lin Y, Wang J.

Eur J Med Chem. 2016 Nov 10;123:226-35. doi: 10.1016/j.ejmech.2016.07.050. Epub 2016 Jul 22.

PMID:
27484511
5.

Effects of imatinib and 5-bromotetrandrine on the reversal of multidrug resistance of the K562/A02 cell line.

Chen BA, Shan XY, Chen J, Xia GH, Xu WL, Schmit M.

Chin J Cancer. 2010 Jun;29(6):591-5.

6.

The short-time treatment with curcumin sufficiently decreases cell viability, induces apoptosis and copper enhances these effects in multidrug-resistant K562/A02 cells.

Lu JJ, Cai YJ, Ding J.

Mol Cell Biochem. 2012 Jan;360(1-2):253-60. doi: 10.1007/s11010-011-1064-2. Epub 2011 Sep 22.

PMID:
21938404
7.

[The study on reversing mechanism of multidrug resistance of K562/A02 cell line by curcumin and erythromycin].

Chang HY, Pan KL, Ma FC, Jiao XY, Zhu HF, Liu JH, Huang Y, Cao YH.

Zhonghua Xue Ye Xue Za Zhi. 2006 Apr;27(4):254-8. Chinese.

PMID:
16875558
8.

Antimultidrug-resistant effect and mechanism of a novel CA-4 analogue MZ3 on leukemia cells.

Xu D, Fang L, Zhu Q, Hu Y, He Q, Yang B.

Pharmazie. 2008 Jul;63(7):528-33.

PMID:
18717489
9.

[Effects of arsenic trioxide on expressions of vascular endothelial growth factor and P-glycoprotein in multidrug resistant leukemia cell line K562/A02].

Liang H, Zhang Y, Zhang JD, Gu J, Ma L, Wang XL, Shen WG.

Zhong Xi Yi Jie He Xue Bao. 2007 Nov;5(6):647-50. Chinese.

10.

Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II.

Xue X, Qu XJ, Gao ZH, Sun CC, Liu HP, Zhao CR, Cheng YN, Lou HX.

Invest New Drugs. 2012 Feb;30(1):212-22. doi: 10.1007/s10637-010-9554-8. Epub 2010 Oct 6.

PMID:
20924640
11.

Chabamide induces cell cycle arrest and apoptosis by the Akt/MAPK pathway and inhibition of P-glycoprotein in K562/ADR cells.

Ren J, Xu Y, Huang Q, Yang J, Yang M, Hu K, Wei K.

Anticancer Drugs. 2015 Jun;26(5):498-507. doi: 10.1097/CAD.0000000000000209.

PMID:
25714087
12.

Reactive oxygen species contribute to TRAIL receptors upregulation; the mechanism for PH II-7 augmenting TRAIL induced apoptosis in leukemia cells.

Peng H, Yuan X, Luo S, Li F, Wei X, Ye Z, Xiong D.

Eur J Pharmacol. 2015 Jan 5;746:344-52. doi: 10.1016/j.ejphar.2014.10.028. Epub 2014 Nov 15.

PMID:
25446561
13.

Inhibition of sorcin reverses multidrug resistance of K562/A02 cells and MCF-7/A02 cells via regulating apoptosis-related proteins.

Hu Y, Cheng X, Li S, Zhou Y, Wang J, Cheng T, Yang M, Xiong D.

Cancer Chemother Pharmacol. 2013 Oct;72(4):789-98. doi: 10.1007/s00280-013-2254-2. Epub 2013 Sep 8.

PMID:
24013575
14.

Synthesis and evaluation of novel podophyllotoxin derivatives as potential antitumor agents.

Cheng WH, Cao B, Shang H, Niu C, Zhang LM, Zhang ZH, Tian DL, Zhang S, Chen H, Zou ZM.

Eur J Med Chem. 2014 Oct 6;85:498-507. doi: 10.1016/j.ejmech.2014.08.006. Epub 2014 Aug 4.

PMID:
25113878
15.

Substituted tetrahydroisoquinoline compound B3 inhibited P-glycoprotein-mediated multidrug resistance in-vitro and in-vivo.

Fang W, Li Y, Cai Y, Kang K, Yan F, Liu G, Huang W.

J Pharm Pharmacol. 2007 Dec;59(12):1649-55.

PMID:
18053326
16.

A novel podophyllotoxin derivative (YB-1EPN) induces apoptosis and down-regulates express of P-glycoprotein in multidrug resistance cell line KBV200.

Chen H, Bi W, Cao B, Yang Z, Chen S, Shang H, Yu P, Yang J.

Eur J Pharmacol. 2010 Feb 10;627(1-3):69-74. doi: 10.1016/j.ejphar.2009.10.056. Epub 2009 Oct 30.

PMID:
19879873
17.

Induction of actin disruption and downregulation of P-glycoprotein expression by solamargine in multidrug-resistant K562/A02 cells.

Li X, Zhao Y, Ji M, Liu SS, Cui M, Lou HX.

Chin Med J (Engl). 2011 Jul 5;124(13):2038-44.

PMID:
22088467
18.

The effects of proteasome inhibitor bortezomib on a P-gp positive leukemia cell line K562/A02.

Lü S, Chen Z, Yang J, Chen L, Zhou H, Xu X, Li J, Han F, Wang J.

Int J Lab Hematol. 2010 Feb;32(1 Pt 1):e123-31. doi: 10.1111/j.1751-553X.2009.01145.x. Epub 2009 Feb 25.

PMID:
19254348
19.

[Arsenic trioxide inhibits P-glycoprotein expression in multidrug-resistant human leukemia K562/ADM cell line that overexpresses mdr-1 gene and enhances their chemotherapeutic sensitivity].

Wei HL, Yao XJ, Li YN, Wang P, Zhao HS, Bai DC, Peng X, Ma LF.

Zhonghua Xue Ye Xue Za Zhi. 2003 Jan;24(1):28-31. Chinese.

PMID:
12679007
20.

Modulation of P-glycoprotein-mediated multidrug resistance in K562 leukemic cells by indole-3-carbinol.

Arora A, Seth K, Kalra N, Shukla Y.

Toxicol Appl Pharmacol. 2005 Feb 1;202(3):237-43.

PMID:
15667829

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