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Greater preexisting interferon γ responses to mycobacterial antigens and lower bacillary load during HIV-associated tuberculosis.

Lahey T, Czechura T, Crabtree S, Arbeit RD, Matee M, Horsburgh CR, MacKenzie T, Bakari M, Pallangyo K, von Reyn CF.

J Infect Dis. 2013 Nov 15;208(10):1629-33. doi: 10.1093/infdis/jit396. Epub 2013 Aug 1.


Interferon γ responses to mycobacterial antigens protect against subsequent HIV-associated tuberculosis.

Lahey T, Sheth S, Matee M, Arbeit R, Horsburgh CR, Mtei L, Mackenzie T, Bakari M, Vuola JM, Pallangyo K, von Reyn CF.

J Infect Dis. 2010 Oct 15;202(8):1265-72. doi: 10.1086/656332.


Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis.

Mzinza DT, Sloan DJ, Jambo KC, Shani D, Kamdolozi M, Wilkinson KA, Wilkinson RJ, Davies GR, Heyderman RS, Mwandumba HC.

Tuberculosis (Edinb). 2015 Jul;95(4):463-9. doi: 10.1016/ Epub 2015 May 28.


Correlation of mycobacterium tuberculosis specific and non-specific quantitative Th1 T-cell responses with bacillary load in a high burden setting.

Theron G, Peter J, Lenders L, van Zyl-Smit R, Meldau R, Govender U, Dheda K.

PLoS One. 2012;7(5):e37436. doi: 10.1371/journal.pone.0037436. Epub 2012 May 22.


Polyantigenic interferon-γ responses are associated with protection from TB among HIV-infected adults with childhood BCG immunization.

Lahey T, Mitchell BK, Arbeit RD, Sheth S, Matee M, Horsburgh CR, MacKenzie T, Mtei L, Bakari M, Vuola JM, Pallangyo K, von Reyn CF.

PLoS One. 2011;6(7):e22074. doi: 10.1371/journal.pone.0022074. Epub 2011 Jul 20.


Lymphocyte proliferation to mycobacterial antigens is detectable across a spectrum of HIV-associated tuberculosis.

Lahey T, Matee M, Mtei L, Bakari M, Pallangyo K, von Reyn CF.

BMC Infect Dis. 2009 Feb 23;9:21. doi: 10.1186/1471-2334-9-21.


Immunogenicity of a protective whole cell mycobacterial vaccine in HIV-infected adults: a phase III study in Tanzania.

Lahey T, Arbeit RD, Bakari M, Horsburgh CR, Matee M, Waddell R, Mtei L, Vuola JM, Pallangyo K, von Reyn CF.

Vaccine. 2010 Nov 10;28(48):7652-8. doi: 10.1016/j.vaccine.2010.09.041. Epub 2010 Sep 25.


The safety and immunogenicity of an adenovirus type 35-vectored TB vaccine in HIV-infected, BCG-vaccinated adults with CD4(+) T cell counts >350 cells/mm(3).

Churchyard GJ, Snowden MA, Hokey D, Dheenadhayalan V, McClain JB, Douoguih M, Pau MG, Sadoff J, Landry B.

Vaccine. 2015 Apr 8;33(15):1890-6. doi: 10.1016/j.vaccine.2015.02.004. Epub 2015 Feb 17.


Gamma interferon production in response to Mycobacterium bovis BCG and Mycobacterium tuberculosis antigens in infants born to human immunodeficiency virus-infected mothers.

Van Rie A, Madhi SA, Heera JR, Meddows-Taylor S, Wendelboe AM, Anthony F, Violari A, Tiemessen CT.

Clin Vaccine Immunol. 2006 Feb;13(2):246-52.


Immunogenicity of an inactivated mycobacterial vaccine for the prevention of HIV-associated tuberculosis: a randomized, controlled trial.

Vuola JM, Ristola MA, Cole B, Järviluoma A, Tvaroha S, Rönkkö T, Rautio O, Arbeit RD, von Reyn CF.

AIDS. 2003 Nov 7;17(16):2351-5.


Baseline mycobacterial immune responses in HIV-infected adults primed with bacille Calmette-Guérin during childhood and entering a tuberculosis booster vaccine trial.

Matee M, Lahey T, Vuola JM, Mtei L, Cole BF, Bakari M, Arbeit RD, Horsburgh CR, Pallangyo K, von Reyn CF.

J Infect Dis. 2007 Jan 1;195(1):118-23. Epub 2006 Nov 20.


Gamma interferon responses induced by a panel of recombinant and purified mycobacterial antigens in healthy, non-mycobacterium bovis BCG-vaccinated Malawian young adults.

Black GF, Weir RE, Chaguluka SD, Warndorff D, Crampin AC, Mwaungulu L, Sichali L, Floyd S, Bliss L, Jarman E, Donovan L, Andersen P, Britton W, Hewinson G, Huygen K, Paulsen J, Singh M, Prestidge R, Fine PE, Dockrell HM.

Clin Diagn Lab Immunol. 2003 Jul;10(4):602-11.


Impact of tuberculosis treatment and antiretroviral therapy on serial RD-1-specific quantitative T-cell readouts (QuantiFERON-TB Gold In-Tube), and relationship to treatment-related outcomes and bacterial burden.

Mthiyane T, Rustomjee R, Pym A, Connolly C, Onyebujoh P, Theron G, Dheda K.

Int J Infect Dis. 2015 Jul;36:46-53. doi: 10.1016/j.ijid.2015.05.006. Epub 2015 May 21.


Early cellular immune response to a new candidate mycobacterial vaccine antigen in childhood tuberculosis.

Schepers K, Dirix V, Mouchet F, Verscheure V, Lecher S, Locht C, Mascart F.

Vaccine. 2015 Feb 18;33(8):1077-83. doi: 10.1016/j.vaccine.2014.12.011. Epub 2015 Jan 9.


A DNA vaccine expressing CFP21 and MPT64 fusion protein enhances BCG-induced protective immunity against Mycobacterium tuberculosis infection in mice.

Wang C, Chen Z, Fu R, Zhang Y, Chen L, Huang L, Li J, Shi C, Fan X.

Med Microbiol Immunol. 2011 Aug;200(3):165-75. doi: 10.1007/s00430-011-0188-z. Epub 2011 Feb 22.


Protection against tuberculosis induced by oral prime with Mycobacterium bovis BCG and intranasal subunit boost based on the vaccine candidate Ag85B-ESAT-6 does not correlate with circulating IFN-gamma producing T-cells.

Badell E, Nicolle F, Clark S, Majlessi L, Boudou F, Martino A, Castello-Branco L, Leclerc C, Lewis DJ, Marsh PD, Gicquel B, Winter N.

Vaccine. 2009 Jan 1;27(1):28-37. doi: 10.1016/j.vaccine.2008.10.034. Epub 2008 Oct 31.


A randomised controlled trial of the effects of albendazole in pregnancy on maternal responses to mycobacterial antigens and infant responses to Bacille Calmette-Guérin (BCG) immunisation [ISRCTN32849447].

Elliott AM, Namujju PB, Mawa PA, Quigley MA, Nampijja M, Nkurunziza PM, Belisle JT, Muwanga M, Whitworth JA; Mother and Baby study team..

BMC Infect Dis. 2005 Dec 21;5:115.


Evaluation of gamma interferon release assays using Mycobacterium tuberculosis antigens for diagnosis of latent and active tuberculosis in Mycobacterium bovis BCG-vaccinated populations.

Zhang S, Shao L, Mo L, Chen J, Wang F, Meng C, Zhong M, Qiu L, Wu M, Weng X, Zhang W.

Clin Vaccine Immunol. 2010 Dec;17(12):1985-90. doi: 10.1128/CVI.00294-10. Epub 2010 Oct 13.


Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination.

Lin MY, Geluk A, Smith SG, Stewart AL, Friggen AH, Franken KL, Verduyn MJ, van Meijgaarden KE, Voskuil MI, Dockrell HM, Huygen K, Ottenhoff TH, Klein MR.

Infect Immun. 2007 Jul;75(7):3523-30. Epub 2007 May 14.


Utility of interferon-gamma ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa.

Lawn SD, Bangani N, Vogt M, Bekker LG, Badri M, Ntobongwana M, Dockrell HM, Wilkinson RJ, Wood R.

BMC Infect Dis. 2007 Aug 28;7:99.

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