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Items: 1 to 20 of 156


Coordinated regulation of actin filament turnover by a high-molecular-weight Srv2/CAP complex, cofilin, profilin, and Aip1.

Balcer HI, Goodman AL, Rodal AA, Smith E, Kugler J, Heuser JE, Goode BL.

Curr Biol. 2003 Dec 16;13(24):2159-69.


ATP-dependent regulation of actin monomer-filament equilibrium by cyclase-associated protein and ADF/cofilin.

Nomura K, Ono S.

Biochem J. 2013 Jul 15;453(2):249-59. doi: 10.1042/BJ20130491.


Cyclase-associated protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells.

Bertling E, Hotulainen P, Mattila PK, Matilainen T, Salminen M, Lappalainen P.

Mol Biol Cell. 2004 May;15(5):2324-34. Epub 2004 Mar 5.


Identification of Arabidopsis cyclase-associated protein 1 as the first nucleotide exchange factor for plant actin.

Chaudhry F, Guérin C, von Witsch M, Blanchoin L, Staiger CJ.

Mol Biol Cell. 2007 Aug;18(8):3002-14. Epub 2007 May 30.


Stochastic severing of actin filaments by actin depolymerizing factor/cofilin controls the emergence of a steady dynamical regime.

Roland J, Berro J, Michelot A, Blanchoin L, Martiel JL.

Biophys J. 2008 Mar 15;94(6):2082-94. Epub 2007 Dec 7.


A cytoskeletal localizing domain in the cyclase-associated protein, CAP/Srv2p, regulates access to a distant SH3-binding site.

Yu J, Wang C, Palmieri SJ, Haarer BK, Field J.

J Biol Chem. 1999 Jul 9;274(28):19985-91.


Mammalian CAP (Cyclase-associated protein) in the world of cell migration: Roles in actin filament dynamics and beyond.

Zhou GL, Zhang H, Field J.

Cell Adh Migr. 2014;8(1):55-9. doi: 10.4161/cam.27479. Epub 2013 Jan 1.


Mammalian homolog of the yeast cyclase associated protein, CAP/Srv2p, regulates actin filament assembly.

Freeman NL, Field J.

Cell Motil Cytoskeleton. 2000 Feb;45(2):106-20.


CAS-1, a C. elegans cyclase-associated protein, is required for sarcomeric actin assembly in striated muscle.

Nomura K, Ono K, Ono S.

J Cell Sci. 2012 Sep 1;125(Pt 17):4077-89. doi: 10.1242/jcs.104950. Epub 2012 May 23.


Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin.

Chaudhry F, Breitsprecher D, Little K, Sharov G, Sokolova O, Goode BL.

Mol Biol Cell. 2013 Jan;24(1):31-41. doi: 10.1091/mbc.E12-08-0589. Epub 2012 Nov 7.


A central role for the WH2 domain of Srv2/CAP in recharging actin monomers to drive actin turnover in vitro and in vivo.

Chaudhry F, Little K, Talarico L, Quintero-Monzon O, Goode BL.

Cytoskeleton (Hoboken). 2010 Feb;67(2):120-33. doi: 10.1002/cm.20429.


A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein.

Mattila PK, Quintero-Monzon O, Kugler J, Moseley JB, Almo SC, Lappalainen P, Goode BL.

Mol Biol Cell. 2004 Nov;15(11):5158-71. Epub 2004 Sep 8.


Mammalian adenylyl cyclase-associated protein 1 (CAP1) regulates cofilin function, the actin cytoskeleton, and cell adhesion.

Zhang H, Ghai P, Wu H, Wang C, Field J, Zhou GL.

J Biol Chem. 2013 Jul 19;288(29):20966-77. doi: 10.1074/jbc.M113.484535. Epub 2013 Jun 4. Erratum in: J Biol Chem. 2013 Sep 27;288(39):28306.


Actin-Depolymerizing Factor and Cofilin-1 Have Unique and Overlapping Functions in Regulating Intestinal Epithelial Junctions and Mucosal Inflammation.

Wang D, Naydenov NG, Feygin A, Baranwal S, Kuemmerle JF, Ivanov AI.

Am J Pathol. 2016 Apr;186(4):844-58. doi: 10.1016/j.ajpath.2015.11.023. Epub 2016 Feb 13.


Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover.

Quintero-Monzon O, Jonasson EM, Bertling E, Talarico L, Chaudhry F, Sihvo M, Lappalainen P, Goode BL.

J Biol Chem. 2009 Apr 17;284(16):10923-34. doi: 10.1074/jbc.M808760200. Epub 2009 Feb 6.


Regulation of cytoskeletal dynamics by actin-monomer-binding proteins.

Paavilainen VO, Bertling E, Falck S, Lappalainen P.

Trends Cell Biol. 2004 Jul;14(7):386-94. Review.


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