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Items: 1 to 20 of 129

1.

Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system.

Morel E, Chamoun Z, Lasiecka ZM, Chan RB, Williamson RL, Vetanovetz C, Dall'Armi C, Simoes S, Point Du Jour KS, McCabe BD, Small SA, Di Paolo G.

Nat Commun. 2013;4:2250. doi: 10.1038/ncomms3250.

2.

ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation.

Edgar JR, Willén K, Gouras GK, Futter CE.

J Cell Sci. 2015 Jul 15;128(14):2520-8. doi: 10.1242/jcs.170233. Epub 2015 May 22.

3.

APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complex.

Currinn H, Guscott B, Balklava Z, Rothnie A, Wassmer T.

Cell Mol Life Sci. 2016 Jan;73(2):393-408. doi: 10.1007/s00018-015-1993-0. Epub 2015 Jul 28.

4.

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.

Andersen OM, Reiche J, Schmidt V, Gotthardt M, Spoelgen R, Behlke J, von Arnim CA, Breiderhoff T, Jansen P, Wu X, Bales KR, Cappai R, Masters CL, Gliemann J, Mufson EJ, Hyman BT, Paul SM, Nykjaer A, Willnow TE.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13461-6. Epub 2005 Sep 7.

5.
6.

Vps27 recruits ESCRT machinery to endosomes during MVB sorting.

Katzmann DJ, Stefan CJ, Babst M, Emr SD.

J Cell Biol. 2003 Aug 4;162(3):413-23.

7.

Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting.

John BA, Meister M, Banning A, Tikkanen R.

FEBS J. 2014 Apr;281(8):2074-87. doi: 10.1111/febs.12763. Epub 2014 Mar 6.

8.

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.

Herskowitz JH, Offe K, Deshpande A, Kahn RA, Levey AI, Lah JJ.

Mol Biol Cell. 2012 Jul;23(14):2645-57. doi: 10.1091/mbc.E12-01-0014. Epub 2012 May 23.

9.

Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain.

Dumanis SB, Burgert T, Caglayan S, Füchtbauer A, Füchtbauer EM, Schmidt V, Willnow TE.

J Neurosci. 2015 Sep 16;35(37):12703-13. doi: 10.1523/JNEUROSCI.0427-15.2015.

10.

Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport.

Pasqual G, Rojek JM, Masin M, Chatton JY, Kunz S.

PLoS Pathog. 2011 Sep;7(9):e1002232. doi: 10.1371/journal.ppat.1002232. Epub 2011 Sep 8. Erratum in: PLoS Pathog. 2011 Sep;7(9). doi: 10.1371/annotation/952387a7-96a0-44f6-98a6-2d7c7b472b0a.

11.

Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex.

Burgos PV, Mardones GA, Rojas AL, daSilva LL, Prabhu Y, Hurley JH, Bonifacino JS.

Dev Cell. 2010 Mar 16;18(3):425-36. doi: 10.1016/j.devcel.2010.01.015.

12.

Golgi defects enhance APP amyloidogenic processing in Alzheimer's disease.

Joshi G, Wang Y.

Bioessays. 2015 Mar;37(3):240-7. doi: 10.1002/bies.201400116. Epub 2014 Dec 28. Review.

13.

Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.

Shrivastava-Ranjan P, Faundez V, Fang G, Rees H, Lah JJ, Levey AI, Kahn RA.

Mol Biol Cell. 2008 Jan;19(1):51-64. Epub 2007 Oct 24.

14.
15.

Receptor-mediated Endocytosis 8 Utilizes an N-terminal Phosphoinositide-binding Motif to Regulate Endosomal Clathrin Dynamics.

Xhabija B, Vacratsis PO.

J Biol Chem. 2015 Aug 28;290(35):21676-89. doi: 10.1074/jbc.M115.644757. Epub 2015 Jul 1.

16.
17.

Sorting receptor SORLA--a trafficking path to avoid Alzheimer disease.

Willnow TE, Andersen OM.

J Cell Sci. 2013 Jul 1;126(Pt 13):2751-60. doi: 10.1242/jcs.125393. Epub 2013 Jun 26. Review.

18.

Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.

Yang GZ, Yang M, Lim Y, Lu JJ, Wang TH, Qi JG, Zhong JH, Zhou XF.

J Neurochem. 2012 Sep;122(5):1010-22. doi: 10.1111/j.1471-4159.2012.07845.x.

19.

Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production.

Lin YC, Wang JY, Wang KC, Liao JY, Cheng IH.

J Neurochem. 2014 Nov;131(4):407-12. doi: 10.1111/jnc.12829. Epub 2014 Aug 13.

20.

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