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Items: 1 to 20 of 220

1.

17β-estradiol promotes the invasion and migration of nuclear estrogen receptor-negative breast cancer cells through cross-talk between GPER1 and CXCR1.

Jiang QF, Wu TT, Yang JY, Dong CR, Wang N, Liu XH, Liu ZM.

J Steroid Biochem Mol Biol. 2013 Nov;138:314-24. doi: 10.1016/j.jsbmb.2013.07.011. Epub 2013 Jul 30.

PMID:
23907016
2.

GPER/ERK&AKT/NF-κB pathway is involved in cadmium-induced proliferation, invasion and migration of GPER-positive thyroid cancer cells.

Zhu P, Liao LY, Zhao TT, Mo XM, Chen GG, Liu ZM.

Mol Cell Endocrinol. 2017 Feb 15;442:68-80. doi: 10.1016/j.mce.2016.12.007. Epub 2016 Dec 9.

PMID:
27940299
3.

Interleukin-8 upregulates integrin β3 expression and promotes estrogen receptor-negative breast cancer cell invasion by activating the PI3K/Akt/NF-κB pathway.

Shao N, Lu Z, Zhang Y, Wang M, Li W, Hu Z, Wang S, Lin Y.

Cancer Lett. 2015 Aug 10;364(2):165-72. doi: 10.1016/j.canlet.2015.05.009. Epub 2015 May 12.

PMID:
25979232
4.

Tamoxifen resistance and metastasis of human breast cancer cells were mediated by the membrane-associated estrogen receptor ER-α36 signaling in vitro.

Gu W, Dong N, Wang P, Shi C, Yang J, Wang J.

Cell Biol Toxicol. 2017 Apr;33(2):183-195. doi: 10.1007/s10565-016-9365-6. Epub 2016 Nov 11.

PMID:
27837347
5.

GPER mediates enhanced cell viability and motility via non-genomic signaling induced by 17β-estradiol in triple-negative breast cancer cells.

Yu T, Liu M, Luo H, Wu C, Tang X, Tang S, Hu P, Yan Y, Wang Z, Tu G.

J Steroid Biochem Mol Biol. 2014 Sep;143:392-403. doi: 10.1016/j.jsbmb.2014.05.003. Epub 2014 May 27.

PMID:
24874276
6.

G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients.

Broselid S, Cheng B, Sjöström M, Lövgren K, Klug-De Santiago HL, Belting M, Jirström K, Malmström P, Olde B, Bendahl PO, Hartman L, Fernö M, Leeb-Lundberg LM.

Clin Cancer Res. 2013 Apr 1;19(7):1681-92. doi: 10.1158/1078-0432.CCR-12-2376.

7.

Heregulin-β1-induced GPR30 upregulation promotes the migration and invasion potential of SkBr3 breast cancer cells via ErbB2/ErbB3-MAPK/ERK pathway.

Ruan SQ, Wang ZH, Wang SW, Fu ZX, Xu KL, Li DB, Zhang SZ.

Biochem Biophys Res Commun. 2012 Apr 6;420(2):385-90. doi: 10.1016/j.bbrc.2012.03.004. Epub 2012 Mar 8.

PMID:
22425775
8.
9.

Interplay of estrogen receptors and GPR30 for the regulation of early membrane initiated transcriptional effects: A pharmacological approach.

Notas G, Kampa M, Pelekanou V, Castanas E.

Steroids. 2012 Aug;77(10):943-50. doi: 10.1016/j.steroids.2011.11.005. Epub 2011 Nov 26.

PMID:
22138208
10.

Ceramide synthases CerS4 and CerS5 are upregulated by 17β-estradiol and GPER1 via AP-1 in human breast cancer cells.

Wegner MS, Wanger RA, Oertel S, Brachtendorf S, Hartmann D, Schiffmann S, Marschalek R, Schreiber Y, Ferreirós N, Geisslinger G, Grösch S.

Biochem Pharmacol. 2014 Dec 15;92(4):577-89. doi: 10.1016/j.bcp.2014.10.007. Epub 2014 Oct 22.

PMID:
25451689
11.

Baicalein suppresses 17-β-estradiol-induced migration, adhesion and invasion of breast cancer cells via the G protein-coupled receptor 30 signaling pathway.

Shang D, Li Z, Zhu Z, Chen H, Zhao L, Wang X, Chen Y.

Oncol Rep. 2015 Apr;33(4):2077-85. doi: 10.3892/or.2015.3786. Epub 2015 Feb 5.

PMID:
25672442
12.

High expression of GPER1, EGFR and CXCR1 is associated with lymph node metastasis in papillary thyroid carcinoma.

Tang C, Yang L, Wang N, Li L, Xu M, Chen GG, Liu ZM.

Int J Clin Exp Pathol. 2014 May 15;7(6):3213-23. eCollection 2014.

13.

GPER mediated estradiol reduces miR-148a to promote HLA-G expression in breast cancer.

Tao S, He H, Chen Q, Yue W.

Biochem Biophys Res Commun. 2014 Aug 15;451(1):74-8. doi: 10.1016/j.bbrc.2014.07.073. Epub 2014 Jul 22.

PMID:
25063027
14.

17β-estradiol inhibits spreading of metastatic cells from granulosa cell tumors through a non-genomic mechanism involving GPER1.

François CM, Wargnier R, Petit F, Goulvent T, Rimokh R, Treilleux I, Ray-Coquard I, Zazzu V, Cohen-Tannoudji J, Guigon CJ.

Carcinogenesis. 2015 May;36(5):564-73. doi: 10.1093/carcin/bgv041. Epub 2015 Mar 30.

16.

The Glycolytic Enzyme PFKFB3 Is Involved in Estrogen-Mediated Angiogenesis via GPER1.

Trenti A, Tedesco S, Boscaro C, Ferri N, Cignarella A, Trevisi L, Bolego C.

J Pharmacol Exp Ther. 2017 Jun;361(3):398-407. doi: 10.1124/jpet.116.238212. Epub 2017 Mar 27.

PMID:
28348059
17.

G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells.

Albanito L, Madeo A, Lappano R, Vivacqua A, Rago V, Carpino A, Oprea TI, Prossnitz ER, Musti AM, Andò S, Maggiolini M.

Cancer Res. 2007 Feb 15;67(4):1859-66.

18.

GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.

Vivacqua A, Romeo E, De Marco P, De Francesco EM, Abonante S, Maggiolini M.

Breast Cancer Res Treat. 2012 Jun;133(3):1025-35. doi: 10.1007/s10549-011-1901-8. Epub 2011 Dec 7.

PMID:
22147081
19.

The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.

Maggiolini M, Vivacqua A, Fasanella G, Recchia AG, Sisci D, Pezzi V, Montanaro D, Musti AM, Picard D, Andò S.

J Biol Chem. 2004 Jun 25;279(26):27008-16. Epub 2004 Apr 16.

20.

MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways.

Keklikoglou I, Koerner C, Schmidt C, Zhang JD, Heckmann D, Shavinskaya A, Allgayer H, Gückel B, Fehm T, Schneeweiss A, Sahin O, Wiemann S, Tschulena U.

Oncogene. 2012 Sep 13;31(37):4150-63. doi: 10.1038/onc.2011.571. Epub 2011 Dec 12.

PMID:
22158050

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