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Items: 1 to 20 of 122

1.

Human cytomegalovirus IE1 protein disrupts interleukin-6 signaling by sequestering STAT3 in the nucleus.

Reitsma JM, Sato H, Nevels M, Terhune SS, Paulus C.

J Virol. 2013 Oct;87(19):10763-76. doi: 10.1128/JVI.01197-13. Epub 2013 Jul 31.

2.

Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like Response.

Harwardt T, Lukas S, Zenger M, Reitberger T, Danzer D, Übner T, Munday DC, Nevels M, Paulus C.

PLoS Pathog. 2016 Jul 7;12(7):e1005748. doi: 10.1371/journal.ppat.1005748. eCollection 2016 Jul.

4.

"Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells.

Trilling M, Le VT, Rashidi-Alavijeh J, Katschinski B, Scheller J, Rose-John S, Androsiac GE, Jonjic S, Poli V, Pfeffer K, Hengel H.

J Immunol. 2014 Jan 1;192(1):447-58. doi: 10.4049/jimmunol.1203516. Epub 2013 Dec 6.

6.

CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication.

Martínez FP, Cruz R, Lu F, Plasschaert R, Deng Z, Rivera-Molina YA, Bartolomei MS, Lieberman PM, Tang Q.

J Virol. 2014 Jul;88(13):7389-401. doi: 10.1128/JVI.00845-14. Epub 2014 Apr 16.

7.

Biphasic regulation of A20 gene expression during human cytomegalovirus infection.

Gu SY, Kim YE, Kwon KM, Han TH, Ahn JH.

Virol J. 2014 Jul 8;11:124. doi: 10.1186/1743-422X-11-124.

8.

Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.

Wu CC, Jiang X, Wang XZ, Liu XJ, Li XJ, Yang B, Ye HQ, Harwardt T, Jiang M, Xia HM, Wang W, Britt WJ, Paulus C, Nevels M, Luo MH.

J Virol. 2018 Aug 16;92(17). pii: e00340-18. doi: 10.1128/JVI.00340-18. Print 2018 Sep 1.

9.

RNA interference-mediated targeting of human cytomegalovirus immediate-early or early gene products inhibits viral replication with differential effects on cellular functions.

Xiaofei E, Stadler BM, Debatis M, Wang S, Lu S, Kowalik TF.

J Virol. 2012 May;86(10):5660-73. doi: 10.1128/JVI.06338-11. Epub 2012 Mar 21.

10.
11.

The 5' Untranslated Region of the Major Immediate Early mRNA Is Necessary for Efficient Human Cytomegalovirus Replication.

Arend KC, Lenarcic EM, Moorman NJ.

J Virol. 2018 Mar 14;92(7). pii: e02128-17. doi: 10.1128/JVI.02128-17. Print 2018 Apr 1.

12.

Chromatin-Remodeling Factor SPOC1 Acts as a Cellular Restriction Factor against Human Cytomegalovirus by Repressing the Major Immediate Early Promoter.

Reichel A, Stilp AC, Scherer M, Reuter N, Lukassen S, Kasmapour B, Schreiner S, Cicin-Sain L, Winterpacht A, Stamminger T.

J Virol. 2018 Jun 29;92(14). pii: e00342-18. doi: 10.1128/JVI.00342-18. Print 2018 Jul 15.

13.

Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection.

Xu S, Schafer X, Munger J.

J Virol. 2016 Apr 14;90(9):4346-4356. doi: 10.1128/JVI.00179-16. Print 2016 May.

14.

Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.

Terhune SS, Moorman NJ, Cristea IM, Savaryn JP, Cuevas-Bennett C, Rout MP, Chait BT, Shenk T.

PLoS Pathog. 2010 Jun 24;6(6):e1000965. doi: 10.1371/journal.ppat.1000965.

17.

Innate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.

Dell'Oste V, Gatti D, Gugliesi F, De Andrea M, Bawadekar M, Lo Cigno I, Biolatti M, Vallino M, Marschall M, Gariglio M, Landolfo S.

J Virol. 2014 Jun;88(12):6970-82. doi: 10.1128/JVI.00384-14. Epub 2014 Apr 2.

18.

Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.

Rechter S, Scott GM, Eickhoff J, Zielke K, Auerochs S, Müller R, Stamminger T, Rawlinson WD, Marschall M.

J Biol Chem. 2009 Mar 27;284(13):8605-13. doi: 10.1074/jbc.M805693200. Epub 2009 Jan 29.

19.

The host ubiquitin-dependent segregase VCP/p97 is required for the onset of human cytomegalovirus replication.

Lin YT, Prendergast J, Grey F.

PLoS Pathog. 2017 May 11;13(5):e1006329. doi: 10.1371/journal.ppat.1006329. eCollection 2017 May.

20.

Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein.

Zalckvar E, Paulus C, Tillo D, Asbach-Nitzsche A, Lubling Y, Winterling C, Strieder N, Mücke K, Goodrum F, Segal E, Nevels M.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13126-31. doi: 10.1073/pnas.1305548110. Epub 2013 Jul 22.

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