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Items: 1 to 20 of 162

1.

Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism.

Hill TD, Cascio MG, Romano B, Duncan M, Pertwee RG, Williams CM, Whalley BJ, Hill AJ.

Br J Pharmacol. 2013 Oct;170(3):679-92. doi: 10.1111/bph.12321.

2.

Cannabidivarin is anticonvulsant in mouse and rat.

Hill AJ, Mercier MS, Hill TD, Glyn SE, Jones NA, Yamasaki Y, Futamura T, Duncan M, Stott CG, Stephens GJ, Williams CM, Whalley BJ.

Br J Pharmacol. 2012 Dec;167(8):1629-42. doi: 10.1111/j.1476-5381.2012.02207.x.

3.
4.

Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol.

Romano B, Borrelli F, Pagano E, Cascio MG, Pertwee RG, Izzo AA.

Phytomedicine. 2014 Apr 15;21(5):631-9. doi: 10.1016/j.phymed.2013.11.006. Epub 2013 Dec 25.

PMID:
24373545
5.

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.

De Petrocellis L, Ligresti A, Moriello AS, Allarà M, Bisogno T, Petrosino S, Stott CG, Di Marzo V.

Br J Pharmacol. 2011 Aug;163(7):1479-94. doi: 10.1111/j.1476-5381.2010.01166.x.

6.
7.

Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.

Jones NA, Hill AJ, Smith I, Bevan SA, Williams CM, Whalley BJ, Stephens GJ.

J Pharmacol Exp Ther. 2010 Feb;332(2):569-77. doi: 10.1124/jpet.109.159145. Epub 2009 Nov 11.

8.

The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy.

Wallace MJ, Blair RE, Falenski KW, Martin BR, DeLorenzo RJ.

J Pharmacol Exp Ther. 2003 Oct;307(1):129-37. Epub 2003 Sep 3.

9.

Effect of ACEA--a selective cannabinoid CB1 receptor agonist on the protective action of different antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model.

Andres-Mach M, Zolkowska D, Barcicka-Klosowska B, Haratym-Maj A, Florek-Luszczki M, Luszczki JJ.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Dec 3;39(2):301-9. doi: 10.1016/j.pnpbp.2012.07.001. Epub 2012 Jul 10.

PMID:
22789660
10.

Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se.

Hill AJ, Jones NA, Smith I, Hill CL, Williams CM, Stephens GJ, Whalley BJ.

Neurosci Lett. 2014 Apr 30;566:269-74. doi: 10.1016/j.neulet.2014.03.013. Epub 2014 Mar 16.

PMID:
24642454
11.

Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders.

Devinsky O, Cilio MR, Cross H, Fernandez-Ruiz J, French J, Hill C, Katz R, Di Marzo V, Jutras-Aswad D, Notcutt WG, Martinez-Orgado J, Robson PJ, Rohrback BG, Thiele E, Whalley B, Friedman D.

Epilepsia. 2014 Jun;55(6):791-802. doi: 10.1111/epi.12631. Epub 2014 May 22. Review.

12.

Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability.

Iannotti FA, Hill CL, Leo A, Alhusaini A, Soubrane C, Mazzarella E, Russo E, Whalley BJ, Di Marzo V, Stephens GJ.

ACS Chem Neurosci. 2014 Nov 19;5(11):1131-41. doi: 10.1021/cn5000524. Epub 2014 Jul 29.

PMID:
25029033
13.

Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects.

Wallace MJ, Wiley JL, Martin BR, DeLorenzo RJ.

Eur J Pharmacol. 2001 Sep 28;428(1):51-7.

PMID:
11779037
14.

Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression.

Amada N, Yamasaki Y, Williams CM, Whalley BJ.

PeerJ. 2013 Nov 21;1:e214. doi: 10.7717/peerj.214. eCollection 2013.

15.

Anticonvulsant properties of methanol leaf extract of Laggera Aurita Linn. F. (Asteraceae) in laboratory animals.

Malami S, Kyari H, Danjuma NM, Ya'u J, Hussaini IM.

J Ethnopharmacol. 2016 Sep 15;191:301-306. doi: 10.1016/j.jep.2016.06.035. Epub 2016 Jun 15.

PMID:
27321277
16.

The role of α₂-adrenoceptors in the anti-convulsant effects of cannabinoids on pentylenetetrazole-induced seizure threshold in mice.

Shafaroodi H, Moezi L, Bahremand A, Dehpour AR.

Eur J Pharmacol. 2013 Aug 15;714(1-3):1-6. doi: 10.1016/j.ejphar.2013.05.040. Epub 2013 Jun 10.

PMID:
23756131
17.

L-type calcium channel mediates anticonvulsant effect of cannabinoids in acute and chronic murine models of seizure.

Naderi N, Ahmad-Molaei L, Mazar-Atabaki A, Ronaghi A, Shirazi-zand Z, Motiei-Langroudi SM, Eslahkar S.

Neurochem Res. 2012 Feb;37(2):279-87. doi: 10.1007/s11064-011-0607-y. Epub 2011 Sep 18.

PMID:
21928146
18.

The interaction of cannabinoids and opioids on pentylenetetrazole-induced seizure threshold in mice.

Shafaroodi H, Samini M, Moezi L, Homayoun H, Sadeghipour H, Tavakoli S, Hajrasouliha AR, Dehpour AR.

Neuropharmacology. 2004 Sep;47(3):390-400.

PMID:
15275828
19.

Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB(1) agonist ACEA in the pentylenetetrazole-induced seizure in mice.

Bahremand A, Nasrabady SE, Shafaroodi H, Ghasemi M, Dehpour AR.

Epilepsy Res. 2009 Apr;84(2-3):110-9. doi: 10.1016/j.eplepsyres.2009.01.003. Epub 2009 Feb 14.

PMID:
19223154
20.

Ultra-low dose cannabinoid antagonist AM251 enhances cannabinoid anticonvulsant effects in the pentylenetetrazole-induced seizure in mice.

Gholizadeh S, Shafaroodi H, Ghasemi M, Bahremand A, Sharifzadeh M, Dehpour AR.

Neuropharmacology. 2007 Nov;53(6):763-70. Epub 2007 Aug 15.

PMID:
17870135

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