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Items: 1 to 20 of 105

1.

Effect of JGK-263 as a new glycogen synthase kinase-3β inhibitor on extrinsic apoptosis pathway in motor neuronal cells.

Jeon GS, Kim JE, Ahn SW, Park KS, Hong YH, Ye IH, Park JS, Kim SH, Lee KW, Kim SM, Sung JJ.

Biochem Biophys Res Commun. 2013 Sep 20;439(2):309-14. doi: 10.1016/j.bbrc.2013.07.080. Epub 2013 Jul 27.

PMID:
23899525
2.

Neuroprotective effects of JGK-263 in transgenic SOD1-G93A mice of amyotrophic lateral sclerosis.

Ahn SW, Jeon GS, Kim MJ, Shon JH, Kim JE, Shin JY, Kim SM, Kim SH, Ye IH, Lee KW, Hong YH, Sung JJ.

J Neurol Sci. 2014 May 15;340(1-2):112-6. doi: 10.1016/j.jns.2014.03.008. Epub 2014 Mar 12.

PMID:
24680562
3.

The neuroprotective effect of the GSK-3β inhibitor and influence on the extrinsic apoptosis in the ALS transgenic mice.

Ahn SW, Kim JE, Park KS, Choi WJ, Hong YH, Kim SM, Kim SH, Lee KW, Sung JJ.

J Neurol Sci. 2012 Sep 15;320(1-2):1-5. doi: 10.1016/j.jns.2012.05.038. Epub 2012 Jun 12.

PMID:
22698482
4.

Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene.

Koh SH, Lee YB, Kim KS, Kim HJ, Kim M, Lee YJ, Kim J, Lee KW, Kim SH.

Eur J Neurosci. 2005 Jul;22(2):301-9.

PMID:
16045483
5.

Glycogen synthase kinase-3beta activity plays very important roles in determining the fate of oxidative stress-inflicted neuronal cells.

Lee KY, Koh SH, Noh MY, Park KW, Lee YJ, Kim SH.

Brain Res. 2007 Jan 19;1129(1):89-99. Epub 2006 Dec 8.

PMID:
17157278
6.

Differential modulation of Akt/glycogen synthase kinase-3beta pathway regulates apoptotic and cytoprotective signaling responses.

Nair VD, Olanow CW.

J Biol Chem. 2008 May 30;283(22):15469-78. doi: 10.1074/jbc.M707238200. Epub 2008 Apr 3.

7.

Glycogen synthase kinase-3 is involved in the regulation of the cell cycle in cerebellar granule cells.

Yeste-Velasco M, Folch J, Trullàs R, Abad MA, Enguita M, Pallàs M, Camins A.

Neuropharmacology. 2007 Aug;53(2):295-307. Epub 2007 May 26.

PMID:
17612578
8.

Glycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3.

Mishra R, Barthwal MK, Sondarva G, Rana B, Wong L, Chatterjee M, Woodgett JR, Rana A.

J Biol Chem. 2007 Oct 19;282(42):30393-405. Epub 2007 Aug 21.

9.

Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons.

Petit-Paitel A, Brau F, Cazareth J, Chabry J.

PLoS One. 2009;4(5):e5491. doi: 10.1371/journal.pone.0005491. Epub 2009 May 11.

10.
11.

Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3.

Koh SH, Noh MY, Kim SH.

Brain Res. 2008 Jan 10;1188:254-62. Epub 2007 Nov 1.

PMID:
18031715
12.

GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis.

Lin CF, Chen CL, Chiang CW, Jan MS, Huang WC, Lin YS.

J Cell Sci. 2007 Aug 15;120(Pt 16):2935-43. Epub 2007 Jul 31.

13.

LPLI inhibits apoptosis upstream of Bax translocation via a GSK-3beta-inactivation mechanism.

Zhang L, Zhang Y, Xing D.

J Cell Physiol. 2010 Jul;224(1):218-28. doi: 10.1002/jcp.22123.

PMID:
20333643
14.

Inhibition of GSK-3beta ameliorates hepatic ischemia-reperfusion injury through GSK-3beta/beta-catenin signaling pathway in mice.

Xia YX, Lu L, Wu ZS, Pu LY, Sun BC, Wang XH.

Hepatobiliary Pancreat Dis Int. 2012 Jun;11(3):278-84.

15.

Glycogen synthase kinase-3beta regulates differentiation-induced apoptosis of human neural progenitor cells.

Jaeger A, Baake J, Weiss DG, Kriehuber R.

Int J Dev Neurosci. 2013 Feb;31(1):61-8. doi: 10.1016/j.ijdevneu.2012.10.005. Epub 2012 Oct 18.

PMID:
23085082
17.

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

Linseman DA, Butts BD, Precht TA, Phelps RA, Le SS, Laessig TA, Bouchard RJ, Florez-McClure ML, Heidenreich KA.

J Neurosci. 2004 Nov 3;24(44):9993-10002.

19.

Recruitment of active glycogen synthase kinase-3 into neuronal lipid rafts.

Sui Z, Kovács AD, Maggirwar SB.

Biochem Biophys Res Commun. 2006 Jul 14;345(4):1643-8. Epub 2006 May 24.

PMID:
16735023
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