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Items: 1 to 20 of 101

1.

ERK5 knock down aggravates detrimental effects of hypothermal stimulation on cardiomyocytes via Bim upregulation.

Wang YS, Zhou J, Liang C, Hong K, Cheng XS, Wu ZG.

Environ Toxicol Pharmacol. 2013 Sep;36(2):724-31. doi: 10.1016/j.etap.2013.06.012. Epub 2013 Jul 4.

PMID:
23896225
2.

BH3-only protein Bim is upregulated and mediates the apoptosis of cardiomyocytes under glucose and oxygen-deprivation conditions.

Huang C, Li J, Hong K, Xia Z, Xu Y, Cheng X.

Cell Biol Int. 2015 Mar;39(3):318-25. doi: 10.1002/cbin.10392. Epub 2014 Nov 5.

PMID:
25319047
3.

Fluid shear stress suppresses TNF-α-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways.

Bin G, Bo Z, Jing W, Jin J, Xiaoyi T, Cong C, Liping A, Jinglin M, Cuifang W, Yonggang C, Yayi X.

Exp Cell Res. 2016 May 1;343(2):208-17. doi: 10.1016/j.yexcr.2016.03.014. Epub 2016 Apr 6.

PMID:
27060196
4.

HCV upregulates Bim through the ROS/JNK signalling pathway, leading to Bax-mediated apoptosis.

Deng L, Chen M, Tanaka M, Ku Y, Itoh T, Shoji I, Hotta H.

J Gen Virol. 2015 Sep;96(9):2670-83. doi: 10.1099/jgv.0.000221. Epub 2015 Jul 3.

PMID:
26296767
5.

Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart.

Kimura TE, Jin J, Zi M, Prehar S, Liu W, Oceandy D, Abe J, Neyses L, Weston AH, Cartwright EJ, Wang X.

Circ Res. 2010 Mar 19;106(5):961-70. doi: 10.1161/CIRCRESAHA.109.209320. Epub 2010 Jan 14.

6.

Up-regulation of pro-apoptotic protein Bim and down-regulation of anti-apoptotic protein Mcl-1 cooperatively mediate enhanced tumor cell death induced by the combination of ERK kinase (MEK) inhibitor and microtubule inhibitor.

Kawabata T, Tanimura S, Asai K, Kawasaki R, Matsumaru Y, Kohno M.

J Biol Chem. 2012 Mar 23;287(13):10289-300. doi: 10.1074/jbc.M111.319426. Epub 2012 Jan 23.

7.

FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.

Hagenbuchner J, Kuznetsov A, Hermann M, Hausott B, Obexer P, Ausserlechner MJ.

J Cell Sci. 2012 Mar 1;125(Pt 5):1191-203. doi: 10.1242/jcs.092098. Epub 2012 Feb 20.

8.

The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM).

Frank DO, Dengjel J, Wilfling F, Kozjak-Pavlovic V, Häcker G, Weber A.

PLoS One. 2015 Apr 15;10(4):e0123341. doi: 10.1371/journal.pone.0123341. eCollection 2015.

9.

Dual regulation of hepatocyte apoptosis by reactive oxygen species: Increases in transcriptional expression and decreases in proteasomal degradation of BimEL.

Ishihara Y, Takeuchi K, Ito F, Shimamoto N.

J Cell Physiol. 2011 Apr;226(4):1007-16. doi: 10.1002/jcp.22414.

PMID:
20857401
10.

EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-delta activities.

Quadros MR, Connelly S, Kari C, Abrams MT, Wickstrom E, Rodeck U.

Cancer Biol Ther. 2006 May;5(5):498-504. Epub 2006 May 6.

PMID:
16582597
11.

CDK1, not ERK1/2 or ERK5, is required for mitotic phosphorylation of BIMEL.

Gilley R, Lochhead PA, Balmanno K, Oxley D, Clark J, Cook SJ.

Cell Signal. 2012 Jan;24(1):170-80. doi: 10.1016/j.cellsig.2011.08.018. Epub 2011 Sep 8.

PMID:
21924351
12.

c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1.

Campone M, Noël B, Couriaud C, Grau M, Guillemin Y, Gautier F, Gouraud W, Charbonnel C, Campion L, Jézéquel P, Braun F, Barré B, Coqueret O, Barillé-Nion S, Juin P.

Mol Cancer. 2011 Sep 7;10:110. doi: 10.1186/1476-4598-10-110.

13.

FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells.

Shukla S, Rizvi F, Raisuddin S, Kakkar P.

Free Radic Biol Med. 2014 Nov;76:185-99. doi: 10.1016/j.freeradbiomed.2014.07.039. Epub 2014 Aug 13.

PMID:
25128467
14.

Role of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer.

Takezawa K, Okamoto I, Nishio K, Jänne PA, Nakagawa K.

Clin Cancer Res. 2011 Apr 15;17(8):2140-8. doi: 10.1158/1078-0432.CCR-10-2798. Epub 2011 Mar 17.

15.

A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation.

Moncunill-Massaguer C, Saura-Esteller J, Pérez-Perarnau A, Palmeri CM, Núñez-Vázquez S, Cosialls AM, González-Gironès DM, Pomares H, Korwitz A, Preciado S, Albericio F, Lavilla R, Pons G, Langer T, Iglesias-Serret D, Gil J.

Oncotarget. 2015 Dec 8;6(39):41750-65. doi: 10.18632/oncotarget.6154.

16.

Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma.

Hu W, Lu SX, Li M, Zhang C, Liu LL, Fu J, Jin JT, Luo RZ, Zhang CZ, Yun JP.

Oncotarget. 2015 Mar 30;6(9):6570-83.

17.

Transforming growth factor-beta1 (TGF-beta1) induces human osteoclast apoptosis by up-regulating Bim.

Houde N, Chamoux E, Bisson M, Roux S.

J Biol Chem. 2009 Aug 28;284(35):23397-404. doi: 10.1074/jbc.M109.019372. Epub 2009 Jul 1.

18.

18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells.

Sharma G, Kar S, Palit S, Das PK.

J Cell Physiol. 2012 May;227(5):1923-31. doi: 10.1002/jcp.22920.

PMID:
21732363
19.

Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells.

Heidari N, Miller AV, Hicks MA, Marking CB, Harada H.

Cell Death Dis. 2012 Jul 19;3:e349. doi: 10.1038/cddis.2012.89.

20.

Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim.

Meng J, Fang B, Liao Y, Chresta CM, Smith PD, Roth JA.

PLoS One. 2010 Sep 27;5(9):e13026. doi: 10.1371/journal.pone.0013026.

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