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SOX2 targets fibronectin 1 to promote cell migration and invasion in ovarian cancer: new molecular leads for therapeutic intervention.

Lou X, Han X, Jin C, Tian W, Yu W, Ding D, Cheng L, Huang B, Jiang H, Lin B.

OMICS. 2013 Oct;17(10):510-8. doi: 10.1089/omi.2013.0058. Epub 2013 Jul 29.


SOX2 enhances the migration and invasion of ovarian cancer cells via Src kinase.

Wang X, Ji X, Chen J, Yan D, Zhang Z, Wang Q, Xi X, Feng Y.

PLoS One. 2014 Jun 17;9(6):e99594. doi: 10.1371/journal.pone.0099594. eCollection 2014.


Overexpression of SOX2 promotes migration, invasion, and epithelial-mesenchymal transition through the Wnt/β-catenin pathway in laryngeal cancer Hep-2 cells.

Yang N, Hui L, Wang Y, Yang H, Jiang X.

Tumour Biol. 2014 Aug;35(8):7965-73. doi: 10.1007/s13277-014-2045-3. Epub 2014 May 16.


Silencing SOX2 induced mesenchymal-epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients.

Han X, Fang X, Lou X, Hua D, Ding W, Foltz G, Hood L, Yuan Y, Lin B.

PLoS One. 2012;7(8):e41335. doi: 10.1371/journal.pone.0041335. Epub 2012 Aug 17.


Overexpression of SOX2 is involved in paclitaxel resistance of ovarian cancer via the PI3K/Akt pathway.

Li Y, Chen K, Li L, Li R, Zhang J, Ren W.

Tumour Biol. 2015 Dec;36(12):9823-8. doi: 10.1007/s13277-015-3561-5. Epub 2015 Jul 11.


Forkhead Box Protein C2 Promotes Epithelial-Mesenchymal Transition, Migration and Invasion in Cisplatin-Resistant Human Ovarian Cancer Cell Line (SKOV3/CDDP).

Li C, Ding H, Tian J, Wu L, Wang Y, Xing Y, Chen M.

Cell Physiol Biochem. 2016;39(3):1098-110. doi: 10.1159/000447818. Epub 2016 Aug 26.


SOX2 promotes the migration and invasion of laryngeal cancer cells by induction of MMP-2 via the PI3K/Akt/mTOR pathway.

Yang N, Hui L, Wang Y, Yang H, Jiang X.

Oncol Rep. 2014 Jun;31(6):2651-9. doi: 10.3892/or.2014.3120. Epub 2014 Apr 2.


Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells.

Yue P, Zhang X, Paladino D, Sengupta B, Ahmad S, Holloway RW, Ingersoll SB, Turkson J.

Oncogene. 2012 May 3;31(18):2309-22. doi: 10.1038/onc.2011.409. Epub 2011 Sep 12.


EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer.

Haslehurst AM, Koti M, Dharsee M, Nuin P, Evans K, Geraci J, Childs T, Chen J, Li J, Weberpals J, Davey S, Squire J, Park PC, Feilotter H.

BMC Cancer. 2012 Mar 19;12:91. doi: 10.1186/1471-2407-12-91.


The critical role of HMGA2 in regulation of EMT in epithelial ovarian carcinomas.

Yan J, Zhang Y, Shi W, Ren C, Liu Y, Pan Y.

Tumour Biol. 2016 Jan;37(1):823-8. doi: 10.1007/s13277-015-3852-x. Epub 2015 Aug 7.


NANOG regulates epithelial-mesenchymal transition and chemoresistance through activation of the STAT3 pathway in epithelial ovarian cancer.

Liu S, Sun J, Cai B, Xi X, Yang L, Zhang Z, Feng Y, Sun Y.

Tumour Biol. 2016 Jul;37(7):9671-80. doi: 10.1007/s13277-016-4848-x. Epub 2016 Jan 22.


Oridonin effectively reverses cisplatin drug resistance in human ovarian cancer cells via induction of cell apoptosis and inhibition of matrix metalloproteinase expression.

Ma S, Tan W, Du B, Liu W, Li W, Che D, Zhang G.

Mol Med Rep. 2016 Apr;13(4):3342-8. doi: 10.3892/mmr.2016.4897. Epub 2016 Feb 16.


Knockdown of eIF4E suppresses cell proliferation, invasion and enhances cisplatin cytotoxicity in human ovarian cancer cells.

Wan J, Shi F, Xu Z, Zhao M.

Int J Oncol. 2015 Dec;47(6):2217-25. doi: 10.3892/ijo.2015.3201. Epub 2015 Oct 13.


FGF16 promotes invasive behavior of SKOV-3 ovarian cancer cells through activation of mitogen-activated protein kinase (MAPK) signaling pathway.

Basu M, Mukhopadhyay S, Chatterjee U, Roy SS.

J Biol Chem. 2014 Jan 17;289(3):1415-28. doi: 10.1074/jbc.M113.535427. Epub 2013 Nov 19.


Role of GPER on proliferation, migration and invasion in ligand-independent manner in human ovarian cancer cell line SKOV3.

Yan Y, Jiang X, Zhao Y, Wen H, Liu G.

Cell Biochem Funct. 2015 Dec;33(8):552-9. doi: 10.1002/cbf.3154. Epub 2015 Nov 3.


FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells.

Chiu WT, Huang YF, Tsai HY, Chen CC, Chang CH, Huang SC, Hsu KF, Chou CY.

Oncotarget. 2015 Feb 10;6(4):2349-65.


Stanniocalcin-2 promotes epithelial-mesenchymal transition and invasiveness in hypoxic human ovarian cancer cells.

Law AY, Wong CK.

Exp Cell Res. 2010 Dec 10;316(20):3425-34. doi: 10.1016/j.yexcr.2010.06.026. Epub 2010 Jul 7.


Establishment of a New Ovarian Cancer Cell Line CA5171.

Chiang YC, Cheng WF, Chang MC, Lu TP, Kuo KT, Lin HP, Hsieh CY, Chen CA.

Reprod Sci. 2015 Jun;22(6):725-34. doi: 10.1177/1933719114557893. Epub 2014 Nov 12.

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