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Items: 1 to 20 of 499

1.

Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest.

Gorshkova IA, Wang H, Orbelyan GA, Goya J, Natarajan V, Beiser DG, Vanden Hoek TL, Berdyshev EV.

Life Sci. 2013 Sep 17;93(9-11):359-66. doi: 10.1016/j.lfs.2013.07.017. Epub 2013 Jul 24.

PMID:
23892195
2.

Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction.

Zhang F, Xia Y, Yan W, Zhang H, Zhou F, Zhao S, Wang W, Zhu D, Xin C, Lee Y, Zhang L, He Y, Gao E, Tao L.

Am J Physiol Heart Circ Physiol. 2016 Jan 15;310(2):H250-61. doi: 10.1152/ajpheart.00372.2015. Epub 2015 Nov 20.

PMID:
26589326
3.

Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes.

Tao R, Zhang J, Vessey DA, Honbo N, Karliner JS.

Cardiovasc Res. 2007 Apr 1;74(1):56-63. Epub 2007 Jan 23.

PMID:
17320845
4.

Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis.

Yang L, Yue S, Yang L, Liu X, Han Z, Zhang Y, Li L.

J Hepatol. 2013 Jul;59(1):114-23. doi: 10.1016/j.jhep.2013.02.021. Epub 2013 Mar 4.

PMID:
23466305
5.

Loss of sphingosine kinase 1/S1P signaling impairs cell growth and survival of neurons and progenitor cells in the developing sensory ganglia.

Meng H, Yuan Y, Lee VM.

PLoS One. 2011;6(11):e27150. doi: 10.1371/journal.pone.0027150. Epub 2011 Nov 9.

6.

Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway.

Loh KC, Leong WI, Carlson ME, Oskouian B, Kumar A, Fyrst H, Zhang M, Proia RL, Hoffman EP, Saba JD.

PLoS One. 2012;7(5):e37218. doi: 10.1371/journal.pone.0037218. Epub 2012 May 14. Erratum in: PLoS One. 2012;7(6): doi/10.1371/annotation/7e7ac57d-30ae-4e49-9138-e3bdbe3491d2.

7.

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

Allende ML, Sasaki T, Kawai H, Olivera A, Mi Y, van Echten-Deckert G, Hajdu R, Rosenbach M, Keohane CA, Mandala S, Spiegel S, Proia RL.

J Biol Chem. 2004 Dec 10;279(50):52487-92. Epub 2004 Sep 30.

8.

Hepatopoietin Cn reduces ethanol-induced hepatoxicity via sphingosine kinase 1 and sphingosine 1-phosphate receptors.

Liu Y, Saiyan S, Men TY, Gao HY, Wen C, Liu Y, Zhou X, Wu CT, Wang LS, Cui CP.

J Pathol. 2013 Aug;230(4):365-76. doi: 10.1002/path.4194.

PMID:
23839903
9.

Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins.

Harijith A, Pendyala S, Reddy NM, Bai T, Usatyuk PV, Berdyshev E, Gorshkova I, Huang LS, Mohan V, Garzon S, Kanteti P, Reddy SP, Raj JU, Natarajan V.

Am J Pathol. 2013 Oct;183(4):1169-1182. doi: 10.1016/j.ajpath.2013.06.018. Epub 2013 Aug 8.

10.

Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells.

Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D.

Circ Res. 2008 Nov 7;103(10):1164-72. doi: 10.1161/01.RES.0000338501.84810.51. Epub 2008 Oct 10.

11.

Vascular endothelium as a contributor of plasma sphingosine 1-phosphate.

Venkataraman K, Lee YM, Michaud J, Thangada S, Ai Y, Bonkovsky HL, Parikh NS, Habrukowich C, Hla T.

Circ Res. 2008 Mar 28;102(6):669-76. doi: 10.1161/CIRCRESAHA.107.165845. Epub 2008 Feb 7.

12.

Inhibition of the SphK1/S1P signaling pathway by melatonin in mice with liver fibrosis and human hepatic stellate cells.

González-Fernández B, Sánchez DI, Crespo I, San-Miguel B, Álvarez M, Tuñón MJ, González-Gallego J.

Biofactors. 2017 Mar;43(2):272-282. doi: 10.1002/biof.1342. Epub 2016 Nov 1.

PMID:
27801960
13.

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients.

Schwab SR, Pereira JP, Matloubian M, Xu Y, Huang Y, Cyster JG.

Science. 2005 Sep 9;309(5741):1735-9.

14.

Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts.

Bu S, Yamanaka M, Pei H, Bielawska A, Bielawski J, Hannun YA, Obeid L, Trojanowska M.

FASEB J. 2006 Jan;20(1):184-6. Epub 2005 Nov 8.

PMID:
16278291
15.

S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart.

Bandhuvula P, Honbo N, Wang GY, Jin ZQ, Fyrst H, Zhang M, Borowsky AD, Dillard L, Karliner JS, Saba JD.

Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1753-61. doi: 10.1152/ajpheart.00946.2010. Epub 2011 Feb 18.

16.

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema.

Diab KJ, Adamowicz JJ, Kamocki K, Rush NI, Garrison J, Gu Y, Schweitzer KS, Skobeleva A, Rajashekhar G, Hubbard WC, Berdyshev EV, Petrache I.

Am J Respir Crit Care Med. 2010 Feb 15;181(4):344-52. doi: 10.1164/rccm.200906-0826OC. Epub 2009 Dec 3.

17.

Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy.

Nguyen-Tran DH, Hait NC, Sperber H, Qi J, Fischer K, Ieronimakis N, Pantoja M, Hays A, Allegood J, Reyes M, Spiegel S, Ruohola-Baker H.

Dis Model Mech. 2014 Jan;7(1):41-54. doi: 10.1242/dmm.013631. Epub 2013 Sep 25.

18.

Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo.

Urtz N, Gaertner F, von Bruehl ML, Chandraratne S, Rahimi F, Zhang L, Orban M, Barocke V, Beil J, Schubert I, Lorenz M, Legate KR, Huwiler A, Pfeilschifter JM, Beerli C, Ledieu D, Persohn E, Billich A, Baumruker T, Mederos y Schnitzler M, Massberg S.

Circ Res. 2015 Jul 31;117(4):376-87. doi: 10.1161/CIRCRESAHA.115.306901. Epub 2015 Jun 30.

19.

Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells.

Albinet V, Bats ML, Huwiler A, Rochaix P, Chevreau C, Ségui B, Levade T, Andrieu-Abadie N.

Oncogene. 2014 Jun 26;33(26):3364-73. doi: 10.1038/onc.2013.303. Epub 2013 Jul 29.

PMID:
23893239
20.

Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models.

Pchejetski D, Golzio M, Bonhoure E, Calvet C, Doumerc N, Garcia V, Mazerolles C, Rischmann P, Teissié J, Malavaud B, Cuvillier O.

Cancer Res. 2005 Dec 15;65(24):11667-75.

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