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Items: 1 to 20 of 113

1.
2.

Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling.

Zhang Y, Won SH, Jiang C, Lee HJ, Jeong SJ, Lee EO, Zhang J, Ye M, Kim SH, Lü J.

Pharm Res. 2012 Jun;29(6):1595-608. doi: 10.1007/s11095-012-0670-3. Epub 2012 Jan 27.

PMID:
22281759
3.

Activation of p53 signaling and inhibition of androgen receptor mediate tanshinone IIA induced G1 arrest in LNCaP prostate cancer cells.

Won SH, Lee HJ, Jeong SJ, Lü J, Kim SH.

Phytother Res. 2012 May;26(5):669-74. doi: 10.1002/ptr.3616. Epub 2011 Oct 13.

PMID:
21997969
4.

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

Won SH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Jung DB, Shin JM, Kwon TR, Yun SM, Lee MH, Choi SH, Lü J, Kim SH.

Biol Pharm Bull. 2010;33(11):1828-34.

5.

Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo.

Chiu SC, Huang SY, Chen SP, Su CC, Chiu TL, Pang CY.

Prostate Cancer Prostatic Dis. 2013 Dec;16(4):315-22. doi: 10.1038/pcan.2013.38. Epub 2013 Sep 17.

PMID:
24042854
6.

Tanshinone IIA induces growth inhibition and apoptosis in gastric cancer in vitro and in vivo.

Chen J, Shi DY, Liu SL, Zhong L.

Oncol Rep. 2012 Feb;27(2):523-8. doi: 10.3892/or.2011.1524. Epub 2011 Oct 27.

PMID:
22038415
7.

Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice.

Gong Y, Li Y, Lu Y, Li L, Abdolmaleky H, Blackburn GL, Zhou JR.

Int J Cancer. 2011 Sep 1;129(5):1042-52. doi: 10.1002/ijc.25678. Epub 2010 Nov 3.

8.

Cytotoxic effect and apoptotic mechanism of tanshinone A, a novel tanshinone derivative, on human erythroleukemic K562 cells.

Zhen X, Cen J, Li YM, Yan F, Guan T, Tang XZ.

Eur J Pharmacol. 2011 Sep 30;667(1-3):129-35. doi: 10.1016/j.ejphar.2011.06.004. Epub 2011 Jun 16.

PMID:
21699893
9.

Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation.

Lee WY, Chiu LC, Yeung JH.

Food Chem Toxicol. 2008 Jan;46(1):328-38. Epub 2007 Aug 21.

PMID:
17892911
10.

Tanshinone IIA isolated from Salvia miltiorrhiza elicits the cell death of human endothelial cells.

Yang LJ, Jeng CJ, Kung HN, Chang CC, Wang AG, Chau GY, Don MJ, Chau YP.

J Biomed Sci. 2005;12(2):347-61.

PMID:
15917998
11.

Tanshinone IIA reduces apoptosis induced by hydrogen peroxide in the human endothelium-derived EA.hy926 cells.

Jia LQ, Yang GL, Ren L, Chen WN, Feng JY, Cao Y, Zhang L, Li XT, Lei P.

J Ethnopharmacol. 2012 Aug 30;143(1):100-8. doi: 10.1016/j.jep.2012.06.007. Epub 2012 Jun 28.

PMID:
22750433
12.

[Inhibition of proliferation and induction of apoptosis by tanshinone II A in NCI-H460 cell].

Hu H, Zhang Y, Huang F, Deng H.

Zhong Yao Cai. 2005 Apr;28(4):301-4. Chinese.

PMID:
16104505
13.

[Apoptosis inducing effect of tanshinone II(A) on human nasopharyngeal carcinoma CNE cells].

Dai Z, Huang D, Shi J, Yu L, Wu Q, Xu Q.

Zhongguo Zhong Yao Za Zhi. 2011 Aug;36(15):2129-33. Chinese.

PMID:
22066455
14.

Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3.

Aghaei M, Karami-Tehrani F, Panjehpour M, Salami S, Fallahian F.

Prostate. 2012 Mar;72(4):361-75. doi: 10.1002/pros.21438. Epub 2011 Jun 8.

PMID:
21656837
15.

Tanshinone IIA exerts antitumor activity against vestibular schwannoma cells by inhibiting the expression of hypoxia-inducible factor-1α.

Kim JY, Song JJ, Kwon BM, Lee JD.

Mol Med Rep. 2015 Sep;12(3):4604-9. doi: 10.3892/mmr.2015.3932. Epub 2015 Jun 15.

PMID:
26080622
16.

New abietane norditerpenoid from Salvia miltiorrhiza with cytotoxic activities.

Yao F, Zhang DW, Qu GW, Li GS, Dai SJ.

J Asian Nat Prod Res. 2012;14(9):913-7. doi: 10.1080/10286020.2012.699962. Epub 2012 Aug 28.

PMID:
22924543
17.

Study on optimisation of extraction process of tanshinone IIA and its mechanism of induction of gastric cancer SGC7901 cell apoptosis.

Hou J, He J, Jin X, Hu T, Zhang Y.

Afr J Tradit Complement Altern Med. 2013 Oct 3;10(6):456-8. eCollection 2013.

18.

Tanshinone IIA improves miR-133 expression through MAPK ERK1/2 pathway in hypoxic cardiac myocytes.

Zhang L, Wu Y, Li Y, Xu C, Li X, Zhu D, Zhang Y, Xing S, Wang H, Zhang Z, Shan H.

Cell Physiol Biochem. 2012;30(4):843-52. doi: 10.1159/000341462. Epub 2012 Aug 10.

19.

Bioassay-guided isolation of fatty acid synthase inhibitory diterpenoids from the roots of Salvia miltiorrhiza Bunge.

Jang TS, Zhang H, Kim G, Kim DW, Min BS, Kang W, Son KH, Na M, Lee SH.

Arch Pharm Res. 2012 Mar;35(3):481-6. doi: 10.1007/s12272-012-0311-8. Epub 2012 Apr 5.

PMID:
22477195
20.

Effect of tanshinone II on cell growth of breast cancer cell line type MCF-7 and MD-MB-231.

Nicolin V, Fancellu G, Valentini R.

Ital J Anat Embryol. 2014;119(1):38-43.

PMID:
25345074

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