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Items: 1 to 20 of 178

1.

Enhancer of zeste homolog 2 (EZH2) promotes progression of cholangiocarcinoma cells by regulating cell cycle and apoptosis.

Nakagawa S, Okabe H, Sakamoto Y, Hayashi H, Hashimoto D, Yokoyama N, Sakamoto K, Kuroki H, Mima K, Nitta H, Imai K, Chikamoto A, Watanabe M, Beppu T, Baba H.

Ann Surg Oncol. 2013 Dec;20 Suppl 3:S667-75. doi: 10.1245/s10434-013-3135-y.

PMID:
23887863
2.

Inhibition of enhancer of zeste homolog 2 (EZH2) expression is associated with decreased tumor cell proliferation, migration, and invasion in endometrial cancer cell lines.

Eskander RN, Ji T, Huynh B, Wardeh R, Randall LM, Hoang B.

Int J Gynecol Cancer. 2013 Jul;23(6):997-1005. doi: 10.1097/IGC.0b013e318296a265.

3.

Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells.

Nakagawa S, Sakamoto Y, Okabe H, Hayashi H, Hashimoto D, Yokoyama N, Tokunaga R, Sakamoto K, Kuroki H, Mima K, Beppu T, Baba H.

Oncol Rep. 2014 Feb;31(2):983-8. doi: 10.3892/or.2013.2922.

PMID:
24337160
4.

Overexpression of enhancer of zeste homolog 2 and MUC1 may be related to malignant behaviour in intraductal papillary neoplasm of the bile duct.

Sasaki M, Matsubara T, Yoneda N, Nomoto K, Tsuneyama K, Sato Y, Nakanuma Y.

Histopathology. 2013 Feb;62(3):446-57. doi: 10.1111/his.12016.

PMID:
23163606
5.

Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells.

Alimova I, Birks DK, Harris PS, Knipstein JA, Venkataraman S, Marquez VE, Foreman NK, Vibhakar R.

Neuro Oncol. 2013 Feb;15(2):149-60. doi: 10.1093/neuonc/nos285.

6.

Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer.

Ishikawa S, Hayashi H, Kinoshita K, Abe M, Kuroki H, Tokunaga R, Tomiyasu S, Tanaka H, Sugita H, Arita T, Yagi Y, Watanabe M, Hirota M, Baba H.

Int J Cancer. 2014 Dec 1;135(11):2528-36. doi: 10.1002/ijc.28672.

7.

EZH2 elevates the proliferation of human cholangiocarcinoma cells through the downregulation of RUNX3.

Tang B, Du J, Li Y, Tang F, Wang Z, He S.

Med Oncol. 2014 Nov;31(11):271. doi: 10.1007/s12032-014-0271-6.

PMID:
25280519
8.

Over-expression of polycomb group protein EZH2 relates to decreased expression of p16 INK4a in cholangiocarcinogenesis in hepatolithiasis.

Sasaki M, Yamaguchi J, Itatsu K, Ikeda H, Nakanuma Y.

J Pathol. 2008 Jun;215(2):175-83. doi: 10.1002/path.2345.

PMID:
18393368
9.

Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells.

Kikuchi J, Takashina T, Kinoshita I, Kikuchi E, Shimizu Y, Sakakibara-Konishi J, Oizumi S, Marquez VE, Nishimura M, Dosaka-Akita H.

Lung Cancer. 2012 Nov;78(2):138-43. doi: 10.1016/j.lungcan.2012.08.003.

10.

Immunostaining for polycomb group protein EZH2 and senescent marker p16INK4a may be useful to differentiate cholangiolocellular carcinoma from ductular reaction and bile duct adenoma.

Sasaki M, Matsubara T, Kakuda Y, Sato Y, Nakanuma Y.

Am J Surg Pathol. 2014 Mar;38(3):364-9. doi: 10.1097/PAS.0000000000000125.

PMID:
24487593
11.

Enhancer of zeste homolog 2 promotes the proliferation and invasion of epithelial ovarian cancer cells.

Li H, Cai Q, Godwin AK, Zhang R.

Mol Cancer Res. 2010 Dec;8(12):1610-8. doi: 10.1158/1541-7786.MCR-10-0398.

12.

siRNA silencing EZH2 reverses cisplatin-resistance of human non-small cell lung and gastric cancer cells.

Zhou W, Wang J, Man WY, Zhang QW, Xu WG.

Asian Pac J Cancer Prev. 2015;16(6):2425-30.

13.

EZH2 promotes malignant behaviors via cell cycle dysregulation and its mRNA level associates with prognosis of patient with non-small cell lung cancer.

Cao W, Ribeiro Rde O, Liu D, Saintigny P, Xia R, Xue Y, Lin R, Mao L, Ren H.

PLoS One. 2012;7(12):e52984. doi: 10.1371/journal.pone.0052984.

14.

EZH2 is a negative prognostic factor and exhibits pro-oncogenic activity in glioblastoma.

Zhang J, Chen L, Han L, Shi Z, Zhang J, Pu P, Kang C.

Cancer Lett. 2015 Jan 28;356(2 Pt B):929-36. doi: 10.1016/j.canlet.2014.11.003.

PMID:
25444902
15.

Inhibition of EZH2 expression is associated with the proliferation, apoptosis, and migration of SW620 colorectal cancer cells in vitro.

He SB, Zhou H, Zhou J, Zhou GQ, Han T, Wan DW, Gu W, Gao L, Zhang Y, Xue XF, Zhang LF, Fei M, Hu SQ, Yang XD, Zhu XG, Wang L, Li DC.

Exp Biol Med (Maywood). 2015 Apr;240(4):458-66. doi: 10.1177/1535370214542215. Erratum in: Exp Biol Med (Maywood). 2015 Apr;240(4):546-55.

16.

EZH2 promotes tumor progression by increasing VEGF expression in clear cell renal cell carcinoma.

Xu ZQ, Zhang L, Gao BS, Wan YG, Zhang XH, Chen B, Wang YT, Sun N, Fu YW.

Clin Transl Oncol. 2015 Jan;17(1):41-9. doi: 10.1007/s12094-014-1195-5.

PMID:
24986100
17.

High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery.

Shi RY, Yang XR, Shen QJ, Yang LX, Xu Y, Qiu SJ, Sun YF, Zhang X, Wang Z, Zhu K, Qin WX, Tang ZY, Fan J, Zhou J.

Cancer. 2013 Mar 1;119(5):993-1003. doi: 10.1002/cncr.27788.

18.

Polycomb repressor complex-2 is a novel target for mesothelioma therapy.

Kemp CD, Rao M, Xi S, Inchauste S, Mani H, Fetsch P, Filie A, Zhang M, Hong JA, Walker RL, Zhu YJ, Ripley RT, Mathur A, Liu F, Yang M, Meltzer PA, Marquez VE, De Rienzo A, Bueno R, Schrump DS.

Clin Cancer Res. 2012 Jan 1;18(1):77-90. doi: 10.1158/1078-0432.CCR-11-0962.

19.

Overexpression of lactate dehydrogenase-A in human intrahepatic cholangiocarcinoma: its implication for treatment.

Yu Y, Liao M, Liu R, Chen J, Feng H, Fu Z.

World J Surg Oncol. 2014 Mar 31;12:78. doi: 10.1186/1477-7819-12-78.

20.

MicroRNA-101 exerts tumor-suppressive functions in non-small cell lung cancer through directly targeting enhancer of zeste homolog 2.

Zhang JG, Guo JF, Liu DL, Liu Q, Wang JJ.

J Thorac Oncol. 2011 Apr;6(4):671-8. doi: 10.1097/JTO.0b013e318208eb35.

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