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Items: 1 to 20 of 81

1.

Extracellular zinc ion regulates transient receptor potential melastatin 5 (TRPM5) channel activation through its interaction with a pore loop domain.

Uchida K, Tominaga M.

J Biol Chem. 2013 Sep 6;288(36):25950-5. doi: 10.1074/jbc.M113.470138. Epub 2013 Jul 24.

2.

Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore.

Yang W, Manna PT, Zou J, Luo J, Beech DJ, Sivaprasadarao A, Jiang LH.

J Biol Chem. 2011 Jul 8;286(27):23789-98. doi: 10.1074/jbc.M111.247478. Epub 2011 May 20.

3.

Negatively charged amino acids near and in transient receptor potential (TRP) domain of TRPM4 channel are one determinant of its Ca2+ sensitivity.

Yamaguchi S, Tanimoto A, Otsuguro K, Hibino H, Ito S.

J Biol Chem. 2014 Dec 19;289(51):35265-82. doi: 10.1074/jbc.M114.606087. Epub 2014 Nov 6.

4.

Triphenylphosphine oxide is a potent and selective inhibitor of the transient receptor potential melastatin-5 ion channel.

Palmer RK, Atwal K, Bakaj I, Carlucci-Derbyshire S, Buber MT, Cerne R, Cortés RY, Devantier HR, Jorgensen V, Pawlyk A, Lee SP, Sprous DG, Zhang Z, Bryant R.

Assay Drug Dev Technol. 2010 Dec;8(6):703-13. doi: 10.1089/adt.2010.0334.

PMID:
21158685
5.

The selectivity filter of the cation channel TRPM4.

Nilius B, Prenen J, Janssens A, Owsianik G, Wang C, Zhu MX, Voets T.

J Biol Chem. 2005 Jun 17;280(24):22899-906. Epub 2005 Apr 21.

6.

Overexpression of human transient receptor potential M5 upregulates endogenous human transient receptor potential A1 in a stable HEK cell line.

Buber MT, Cerne R, Cortés RY, Bryant RW, Lee SP.

Assay Drug Dev Technol. 2010 Dec;8(6):695-702. doi: 10.1089/adt.2010.0316. Epub 2010 Dec 6.

PMID:
21133676
7.

Differential effects of bitter compounds on the taste transduction channels TRPM5 and IP3 receptor type 3.

Gees M, Alpizar YA, Luyten T, Parys JB, Nilius B, Bultynck G, Voets T, Talavera K.

Chem Senses. 2014 May;39(4):295-311. doi: 10.1093/chemse/bjt115. Epub 2014 Jan 22.

PMID:
24452633
9.

TRPM5 and taste transduction.

Liman ER.

Handb Exp Pharmacol. 2007;(179):287-98. Review.

PMID:
17217064
10.

Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents.

Tóth B, Csanády L.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13440-5. doi: 10.1073/pnas.1204702109. Epub 2012 Jul 30.

11.

Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.

Lambert S, Drews A, Rizun O, Wagner TF, Lis A, Mannebach S, Plant S, Portz M, Meissner M, Philipp SE, Oberwinkler J.

J Biol Chem. 2011 Apr 8;286(14):12221-33. doi: 10.1074/jbc.M110.202945. Epub 2011 Jan 28.

12.

The transduction channel TRPM5 is gated by intracellular calcium in taste cells.

Zhang Z, Zhao Z, Margolskee R, Liman E.

J Neurosci. 2007 May 23;27(21):5777-86.

13.

TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i.

Prawitt D, Monteilh-Zoller MK, Brixel L, Spangenberg C, Zabel B, Fleig A, Penner R.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15166-71. Epub 2003 Nov 21.

14.

Heat activation of TRPM5 underlies thermal sensitivity of sweet taste.

Talavera K, Yasumatsu K, Voets T, Droogmans G, Shigemura N, Ninomiya Y, Margolskee RF, Nilius B.

Nature. 2005 Dec 15;438(7070):1022-5.

PMID:
16355226
15.

Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2.

Xia R, Mei ZZ, Mao HJ, Yang W, Dong L, Bradley H, Beech DJ, Jiang LH.

J Biol Chem. 2008 Oct 10;283(41):27426-32. doi: 10.1074/jbc.M801049200. Epub 2008 Aug 7.

16.

TRPM5.

Liman ER.

Handb Exp Pharmacol. 2014;222:489-502. doi: 10.1007/978-3-642-54215-2_19. Review.

PMID:
24756718
17.

9-phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels.

Grand T, Demion M, Norez C, Mettey Y, Launay P, Becq F, Bois P, Guinamard R.

Br J Pharmacol. 2008 Apr;153(8):1697-705. doi: 10.1038/bjp.2008.38. Epub 2008 Feb 25.

18.

Dual effect of Zn2+ on multiple types of voltage-dependent Ca2+ currents in rat palaeocortical neurons.

Magistretti J, Castelli L, Taglietti V, Tanzi F.

Neuroscience. 2003;117(2):249-64.

PMID:
12614668
19.
20.

Divalent copper is a potent extracellular blocker for TRPM2 channel.

Zeng B, Chen GL, Xu SZ.

Biochem Biophys Res Commun. 2012 Jul 27;424(2):279-84. doi: 10.1016/j.bbrc.2012.06.107. Epub 2012 Jun 27.

PMID:
22750002

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