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Items: 1 to 20 of 70

1.

Sequence-specific inhibition of a nonspecific protease.

Logsdon LA, Urbach AR.

J Am Chem Soc. 2013 Aug 7;135(31):11414-6. doi: 10.1021/ja406032x. Epub 2013 Jul 29.

PMID:
23883194
2.

Nanomolar binding of peptides containing noncanonical amino acids by a synthetic receptor.

Logsdon LA, Schardon CL, Ramalingam V, Kwee SK, Urbach AR.

J Am Chem Soc. 2011 Oct 26;133(42):17087-92. doi: 10.1021/ja207825y. Epub 2011 Oct 3.

PMID:
21967539
3.

Molecular recognition of insulin by a synthetic receptor.

Chinai JM, Taylor AB, Ryno LM, Hargreaves ND, Morris CA, Hart PJ, Urbach AR.

J Am Chem Soc. 2011 Jun 15;133(23):8810-3. doi: 10.1021/ja201581x. Epub 2011 Apr 7.

4.

Predictive recognition of native proteins by cucurbit[7]uril in a complex mixture.

Li W, Bockus AT, Vinciguerra B, Isaacs L, Urbach AR.

Chem Commun (Camb). 2016 Jun 30;52(55):8537-40. doi: 10.1039/c6cc03193e.

PMID:
27311878
5.

Molecular Recognition of Methionine-Terminated Peptides by Cucurbit[8]uril.

Hirani Z, Taylor HF, Babcock EF, Bockus AT, Varnado CD Jr, Bielawski CW, Urbach AR.

J Am Chem Soc. 2018 Sep 26;140(38):12263-12269. doi: 10.1021/jacs.8b07865. Epub 2018 Sep 17.

6.

Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250.

Fournié-Zaluski MC, Poras H, Roques BP, Nakajima Y, Ito K, Yoshimoto T.

Acta Crystallogr D Biol Crystallogr. 2009 Aug;65(Pt 8):814-22. doi: 10.1107/S090744490901779X. Epub 2009 Jul 17.

PMID:
19622865
7.

Cyclic enediyne-amino acid chimeras as new aminopeptidase N inhibitors.

Gredičak M, Abramić M, Jerić I.

Amino Acids. 2012 Nov;43(5):2087-100. doi: 10.1007/s00726-012-1292-0. Epub 2012 Apr 18.

PMID:
22526243
8.

Sequence-specific recognition and cooperative dimerization of N-terminal aromatic peptides in aqueous solution by a synthetic host.

Heitmann LM, Taylor AB, Hart PJ, Urbach AR.

J Am Chem Soc. 2006 Sep 27;128(38):12574-81.

PMID:
16984208
9.

Structure and activity of CPNGRC: a modified CD13/APN peptidic homing motif.

Plesniak LA, Salzameda B, Hinderberger H, Regan E, Kahn J, Mills SA, Teriete P, Yao Y, Jennings P, Marassi F, Adams JA.

Chem Biol Drug Des. 2010 Jun;75(6):551-62. doi: 10.1111/j.1747-0285.2010.00974.x. Epub 2010 Mar 30.

10.

Crystal structure of aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli and conformational change of methionine 260 involved in substrate recognition.

Ito K, Nakajima Y, Onohara Y, Takeo M, Nakashima K, Matsubara F, Ito T, Yoshimoto T.

J Biol Chem. 2006 Nov 3;281(44):33664-76. Epub 2006 Aug 2.

11.

Supramolecular dimerisation of middle-chain Phe pentapeptides via CB[8] host-guest homoternary complex formation.

Sonzini S, Ryan ST, Scherman OA.

Chem Commun (Camb). 2013 Oct 9;49(78):8779-81. doi: 10.1039/c3cc45420g.

PMID:
23963082
12.

Novel aminopeptidase N (APN/CD13) inhibitors derived from 3-phenylalanyl-N'-substituted-2,6-piperidinedione.

Zhang X, Fang H, Zhu H, Wang X, Zhang L, Li M, Li Q, Yuan Y, Xu W.

Bioorg Med Chem. 2010 Aug 15;18(16):5981-7. doi: 10.1016/j.bmc.2010.06.078. Epub 2010 Jun 26.

PMID:
20637634
13.

Sequence-specific, nanomolar peptide binding via cucurbit[8]uril-induced folding and inclusion of neighboring side chains.

Smith LC, Leach DG, Blaylock BE, Ali OA, Urbach AR.

J Am Chem Soc. 2015 Mar 18;137(10):3663-9. doi: 10.1021/jacs.5b00718. Epub 2015 Mar 5.

PMID:
25710854
14.

Sequence recognition and self-sorting of a dipeptide by cucurbit[6]uril and cucurbit[7]uril.

Rekharsky MV, Yamamura H, Ko YH, Selvapalam N, Kim K, Inoue Y.

Chem Commun (Camb). 2008 May 21;(19):2236-8. doi: 10.1039/b719902c. Epub 2008 Mar 10.

PMID:
18463751
15.

Determining protease substrate selectivity and inhibition by label-free supramolecular tandem enzyme assays.

Ghale G, Ramalingam V, Urbach AR, Nau WM.

J Am Chem Soc. 2011 May 18;133(19):7528-35. doi: 10.1021/ja2013467. Epub 2011 Apr 22.

PMID:
21513303
17.

Structural basis for multifunctional roles of mammalian aminopeptidase N.

Chen L, Lin YL, Peng G, Li F.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17966-71. doi: 10.1073/pnas.1210123109. Epub 2012 Oct 15.

18.

Laeverin/aminopeptidase Q, a novel bestatin-sensitive leucine aminopeptidase belonging to the M1 family of aminopeptidases.

Maruyama M, Hattori A, Goto Y, Ueda M, Maeda M, Fujiwara H, Tsujimoto M.

J Biol Chem. 2007 Jul 13;282(28):20088-96. Epub 2007 May 24.

19.

Novel potent 2,5-pyrrolidinedione peptidomimetics as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.

Li Q, Fang H, Wang X, Hu G, Wang Q, Xu W.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):850-3. doi: 10.1016/j.bmcl.2011.12.048. Epub 2011 Dec 16.

PMID:
22206607
20.

Design, synthesis and biological evaluation of novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as aminopeptidase N/CD13 inhibitors.

Zhang X, Zhang J, Zhang L, Feng J, Xu Y, Yuan Y, Fang H, Xu W.

Bioorg Med Chem. 2011 Oct 15;19(20):6015-25. doi: 10.1016/j.bmc.2011.08.041. Epub 2011 Aug 24.

PMID:
21911297

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