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Items: 1 to 20 of 110


Cost of rNTP/dNTP pool imbalance at the replication fork.

Yao NY, Schroeder JW, Yurieva O, Simmons LA, O'Donnell ME.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):12942-7. doi: 10.1073/pnas.1309506110. Epub 2013 Jul 23.


Investigating the mechanisms of ribonucleotide excision repair in Escherichia coli.

Vaisman A, McDonald JP, Noll S, Huston D, Loeb G, Goodman MF, Woodgate R.

Mutat Res. 2014 Mar;761:21-33. doi: 10.1016/j.mrfmmm.2014.01.005. Epub 2014 Feb 1.


Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol V.

McDonald JP, Vaisman A, Kuban W, Goodman MF, Woodgate R.

PLoS Genet. 2012;8(11):e1003030. doi: 10.1371/journal.pgen.1003030. Epub 2012 Nov 8.


Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing DNA template.

Nguyen LA, Domaoal RA, Kennedy EM, Kim DH, Schinazi RF, Kim B.

Antiviral Res. 2015 Mar;115:75-82. doi: 10.1016/j.antiviral.2014.12.016. Epub 2014 Dec 31.


Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair.

Vaisman A, McDonald JP, Huston D, Kuban W, Liu L, Van Houten B, Woodgate R.

PLoS Genet. 2013 Nov;9(11):e1003878. doi: 10.1371/journal.pgen.1003878. Epub 2013 Nov 7.


Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε.

Clark AB, Lujan SA, Kissling GE, Kunkel TA.

DNA Repair (Amst). 2011 May 5;10(5):476-82. doi: 10.1016/j.dnarep.2011.02.001. Epub 2011 Mar 16.


Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases.

Nick McElhinny SA, Watts BE, Kumar D, Watt DL, Lundström EB, Burgers PM, Johansson E, Chabes A, Kunkel TA.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4949-54. doi: 10.1073/pnas.0914857107. Epub 2010 Mar 1.


Ribonucleotides are signals for mismatch repair of leading-strand replication errors.

Lujan SA, Williams JS, Clausen AR, Clark AB, Kunkel TA.

Mol Cell. 2013 May 9;50(3):437-43. doi: 10.1016/j.molcel.2013.03.017. Epub 2013 Apr 18.


Ribonucleotide incorporation by yeast DNA polymerase ζ.

Makarova AV, Nick McElhinny SA, Watts BE, Kunkel TA, Burgers PM.

DNA Repair (Amst). 2014 Jun;18:63-7. doi: 10.1016/j.dnarep.2014.02.017. Epub 2014 Mar 24.


Frequent incorporation of ribonucleotides during HIV-1 reverse transcription and their attenuated repair in macrophages.

Kennedy EM, Amie SM, Bambara RA, Kim B.

J Biol Chem. 2012 Apr 20;287(17):14280-8. doi: 10.1074/jbc.M112.348482. Epub 2012 Mar 1.


Effect of ribonucleotides embedded in a DNA template on HIV-1 reverse transcription kinetics and fidelity.

Daddacha W, Noble E, Nguyen LA, Kennedy EM, Kim B.

J Biol Chem. 2013 May 3;288(18):12522-32. doi: 10.1074/jbc.M113.458398. Epub 2013 Mar 11.


Ribonucleotides as nucleotide excision repair substrates.

Cai Y, Geacintov NE, Broyde S.

DNA Repair (Amst). 2014 Jan;13:55-60. doi: 10.1016/j.dnarep.2013.10.010. Epub 2013 Nov 26.


Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair.

Ghodgaonkar MM, Lazzaro F, Olivera-Pimentel M, Artola-Borán M, Cejka P, Reijns MA, Jackson AP, Plevani P, Muzi-Falconi M, Jiricny J.

Mol Cell. 2013 May 9;50(3):323-32. doi: 10.1016/j.molcel.2013.03.019. Epub 2013 Apr 18.


RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA.

Lazzaro F, Novarina D, Amara F, Watt DL, Stone JE, Costanzo V, Burgers PM, Kunkel TA, Plevani P, Muzi-Falconi M.

Mol Cell. 2012 Jan 13;45(1):99-110. doi: 10.1016/j.molcel.2011.12.019.


Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ.

Clausen AR, Zhang S, Burgers PM, Lee MY, Kunkel TA.

DNA Repair (Amst). 2013 Feb 1;12(2):121-7. doi: 10.1016/j.dnarep.2012.11.006. Epub 2012 Dec 12.


Steric gate residues of Y-family DNA polymerases DinB and pol kappa are crucial for dNTP-induced conformational change.

Nevin P, Engen JR, Beuning PJ.

DNA Repair (Amst). 2015 May;29:65-73. doi: 10.1016/j.dnarep.2015.01.012. Epub 2015 Feb 4.


Mispaired rNMPs in DNA are mutagenic and are targets of mismatch repair and RNases H.

Shen Y, Koh KD, Weiss B, Storici F.

Nat Struct Mol Biol. 2011 Dec 4;19(1):98-104. doi: 10.1038/nsmb.2176.


Escherichia coli UmuC active site mutants: effects on translesion DNA synthesis, mutagenesis and cell survival.

Kuban W, Vaisman A, McDonald JP, Karata K, Yang W, Goodman MF, Woodgate R.

DNA Repair (Amst). 2012 Sep 1;11(9):726-32. doi: 10.1016/j.dnarep.2012.06.005. Epub 2012 Jul 10.


Stimulation of mutagenesis by proportional deoxyribonucleoside triphosphate accumulation in Escherichia coli.

Wheeler LJ, Rajagopal I, Mathews CK.

DNA Repair (Amst). 2005 Dec 8;4(12):1450-6. Epub 2005 Oct 3.


Balancing eukaryotic replication asymmetry with replication fidelity.

Kunkel TA.

Curr Opin Chem Biol. 2011 Oct;15(5):620-6. doi: 10.1016/j.cbpa.2011.07.025. Epub 2011 Aug 19. Review.

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