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Items: 1 to 20 of 106

1.

Taming neonatal hypoxic-ischemic brain injury by intranasal delivery of plasminogen activator inhibitor-1.

Yang D, Sun YY, Lin X, Baumann JM, Warnock M, Lawrence DA, Kuan CY.

Stroke. 2013 Sep;44(9):2623-2627. doi: 10.1161/STROKEAHA.113.001233. Epub 2013 Jul 23.

2.

Therapeutic administration of plasminogen activator inhibitor-1 prevents hypoxic-ischemic brain injury in newborns.

Yang D, Nemkul N, Shereen A, Jone A, Dunn RS, Lawrence DA, Lindquist D, Kuan CY.

J Neurosci. 2009 Jul 8;29(27):8669-74. doi: 10.1523/JNEUROSCI.1117-09.2009.

3.

Anti-tissue plasminogen activator (tPA) as an effective therapy of neonatal hypoxia-ischemia with and without inflammation.

Yang D, Kuan CY.

CNS Neurosci Ther. 2015 Apr;21(4):367-73. doi: 10.1111/cns.12365. Epub 2014 Dec 5. Review.

4.

Intranasal delivery of cell-penetrating anti-NF-κB peptides (Tat-NBD) alleviates infection-sensitized hypoxic-ischemic brain injury.

Yang D, Sun YY, Lin X, Baumann JM, Dunn RS, Lindquist DM, Kuan CY.

Exp Neurol. 2013 Sep;247:447-455. doi: 10.1016/j.expneurol.2013.01.015. Epub 2013 Jan 23.

5.

Plasminogen activator inhibitor-1 mitigates brain injury in a rat model of infection-sensitized neonatal hypoxia-ischemia.

Yang D, Sun YY, Nemkul N, Baumann JM, Shereen A, Dunn RS, Wills-Karp M, Lawrence DA, Lindquist DM, Kuan CY.

Cereb Cortex. 2013 May;23(5):1218-29. doi: 10.1093/cercor/bhs115. Epub 2012 May 3.

6.

Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns.

Yang D, Sun YY, Bhaumik SK, Li Y, Baumann JM, Lin X, Zhang Y, Lin SH, Dunn RS, Liu CY, Shie FS, Lee YH, Wills-Karp M, Chougnet CA, Kallapur SG, Lewkowich IP, Lindquist DM, Murali-Krishna K, Kuan CY.

J Neurosci. 2014 Dec 3;34(49):16467-81. doi: 10.1523/JNEUROSCI.2582-14.2014.

7.

Sestrin2 induced by hypoxia inducible factor1 alpha protects the blood-brain barrier via inhibiting VEGF after severe hypoxic-ischemic injury in neonatal rats.

Shi X, Doycheva DM, Xu L, Tang J, Yan M, Zhang JH.

Neurobiol Dis. 2016 Nov;95:111-21. doi: 10.1016/j.nbd.2016.07.016. Epub 2016 Jul 16.

8.

Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats.

Lin S, Fan LW, Rhodes PG, Cai Z.

Exp Neurol. 2009 Jun;217(2):361-70. doi: 10.1016/j.expneurol.2009.03.021. Epub 2009 Mar 28.

9.

Deleterious effects of plasminogen activators in neonatal cerebral hypoxia-ischemia.

Adhami F, Yu D, Yin W, Schloemer A, Burns KA, Liao G, Degen JL, Chen J, Kuan CY.

Am J Pathol. 2008 Jun;172(6):1704-16. doi: 10.2353/ajpath.2008.070979. Epub 2008 May 8.

10.

Vitexin reduces hypoxia-ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model.

Min JW, Hu JJ, He M, Sanchez RM, Huang WX, Liu YQ, Bsoul NB, Han S, Yin J, Liu WH, He XH, Peng BW.

Neuropharmacology. 2015 Dec;99:38-50. doi: 10.1016/j.neuropharm.2015.07.007. Epub 2015 Jul 14.

PMID:
26187393
11.

TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain.

Wang LW, Chang YC, Chen SJ, Tseng CH, Tu YF, Liao NS, Huang CC, Ho CJ.

J Neuroinflammation. 2014 Dec 24;11:215. doi: 10.1186/s12974-014-0215-2.

12.

Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain.

Chen W, Hartman R, Ayer R, Marcantonio S, Kamper J, Tang J, Zhang JH.

J Neurochem. 2009 Nov;111(3):726-36. doi: 10.1111/j.1471-4159.2009.06362.x. Epub 2009 Aug 27.

13.

Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic-ischemic brain injury.

Osredkar D, Thoresen M, Maes E, Flatebø T, Elstad M, Sabir H.

Resuscitation. 2014 Apr;85(4):567-72. doi: 10.1016/j.resuscitation.2013.12.006. Epub 2013 Dec 19.

PMID:
24361672
14.

MicroRNA-210 Suppresses Junction Proteins and Disrupts Blood-Brain Barrier Integrity in Neonatal Rat Hypoxic-Ischemic Brain Injury.

Ma Q, Dasgupta C, Li Y, Huang L, Zhang L.

Int J Mol Sci. 2017 Jun 24;18(7). pii: E1356. doi: 10.3390/ijms18071356.

15.

Intranasal administration of aTf protects and repairs the neonatal white matter after a cerebral hypoxic-ischemic event.

Guardia Clausi M, Paez PM, Campagnoni AT, Pasquini LA, Pasquini JM.

Glia. 2012 Oct;60(10):1540-54. doi: 10.1002/glia.22374. Epub 2012 Jun 26.

PMID:
22736466
16.

NF-κB Signaling is Involved in the Effects of Intranasally Engrafted Human Neural Stem Cells on Neurofunctional Improvements in Neonatal Rat Hypoxic-Ischemic Encephalopathy.

Ji G, Liu M, Zhao XF, Liu XY, Guo QL, Guan ZF, Zhou HG, Guo JC.

CNS Neurosci Ther. 2015 Dec;21(12):926-35. doi: 10.1111/cns.12441. Epub 2015 Aug 8.

PMID:
26255634
17.

The inhibition of Cdk5 activity after hypoxia/ischemia injury reduces infarct size and promotes functional recovery in neonatal rats.

Tan X, Chen Y, Li J, Li X, Miao Z, Xin N, Zhu J, Ge W, Feng Y, Xu X.

Neuroscience. 2015 Apr 2;290:552-60. doi: 10.1016/j.neuroscience.2015.01.054. Epub 2015 Feb 7.

PMID:
25665755
18.

Glucocorticoids Protect Neonatal Rat Brain in Model of Hypoxic-Ischemic Encephalopathy (HIE).

Harding B, Conception K, Li Y, Zhang L.

Int J Mol Sci. 2016 Dec 22;18(1). pii: E17. doi: 10.3390/ijms18010017.

19.

Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation.

Tu YF, Tsai YS, Wang LW, Wu HC, Huang CC, Ho CJ.

J Neuroinflammation. 2011 Apr 25;8:40. doi: 10.1186/1742-2094-8-40.

20.

[Changes and significance of endogenous tissue plasminogen activators in cerebral hypoxia-ischemia in neonatal rats].

Yu D, Mao M, Lei MY.

Zhongguo Dang Dai Er Ke Za Zhi. 2008 Oct;10(5):651-5. Chinese.

PMID:
18947492

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