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Items: 1 to 20 of 115

1.

Acotiamide: first global approval.

Nowlan ML, Scott LJ.

Drugs. 2013 Aug;73(12):1377-83. doi: 10.1007/s40265-013-0100-9. Erratum in: Drugs. 2014 Jun;74(9):1059. Nolan, Mary L [corrected to Nowlan, Mary L].

PMID:
23881665
2.

Acotiamide (Z-338) as a possible candidate for the treatment of functional dyspepsia.

Suzuki H, Hibi T.

Neurogastroenterol Motil. 2010 Jun;22(6):595-9. doi: 10.1111/j.1365-2982.2010.01486.x. Review.

PMID:
20553562
3.

Acotiamide, a novel gastroprokinetic for the treatment of patients with functional dyspepsia: postprandial distress syndrome.

Altan E, Masaoka T, Farré R, Tack J.

Expert Rev Gastroenterol Hepatol. 2012 Sep;6(5):533-44. doi: 10.1586/egh.12.34. Review.

PMID:
23061703
4.

A double-blind placebo controlled study of acotiamide hydrochloride for efficacy on gastrointestinal motility of patients with functional dyspepsia.

Nakamura K, Tomita T, Oshima T, Asano H, Yamasaki T, Okugawa T, Kondo T, Kono T, Tozawa K, Ohda Y, Fukui H, Kazuhito F, Hirota S, Watari J, Miwa H.

J Gastroenterol. 2017 May;52(5):602-610. doi: 10.1007/s00535-016-1260-7. Epub 2016 Sep 17.

PMID:
27639387
5.

[Pharmacological and clinical profile of acotiamide hydrochloride hydrate (Acofide(®) Tablets 100 mg), a novel therapeutic agent for functional dyspepsia (FD)].

Matsunaga Y, Tanaka T, Saito Y, Kato H, Takei M.

Nihon Yakurigaku Zasshi. 2014 Feb;143(2):84-94. Review. Japanese. No abstract available.

PMID:
24531902
6.

Acotiamide (Z-338, YM443), a new drug for the treatment of functional dyspepsia.

Tack J, Janssen P.

Expert Opin Investig Drugs. 2011 May;20(5):701-12. doi: 10.1517/13543784.2011.562890. Epub 2011 Mar 22. Review.

PMID:
21417958
7.

Emerging treatments in neurogastroenterology: Acotiamade, a novel treatment option for functional dyspepsia.

Matsushita M, Masaoka T, Suzuki H.

Neurogastroenterol Motil. 2016 May;28(5):631-8. doi: 10.1111/nmo.12756. Epub 2016 Jan 5. Review.

PMID:
26730749
8.

Acotiamide Hydrochloride, a Therapeutic Agent for Functional Dyspepsia, Enhances Acetylcholine-induced Contraction via Inhibition of Acetylcholinesterase Activity in Circular Muscle Strips of Guinea Pig Stomach.

Ito K, Kawachi M, Matsunaga Y, Hori Y, Ozaki T, Nagahama K, Hirayama M, Kawabata Y, Shiraishi Y, Takei M, Tanaka T.

Drug Res (Stuttg). 2016 Apr;66(4):196-202. doi: 10.1055/s-0035-1564084. Epub 2015 Sep 29.

PMID:
26418413
9.

Therapeutic efficacy of acotiamide in patients with functional dyspepsia based on enhanced postprandial gastric accommodation and emptying: randomized controlled study evaluation by real-time ultrasonography.

Kusunoki H, Haruma K, Manabe N, Imamura H, Kamada T, Shiotani A, Hata J, Sugioka H, Saito Y, Kato H, Tack J.

Neurogastroenterol Motil. 2012 Jun;24(6):540-5, e250-1. doi: 10.1111/j.1365-2982.2012.01897.x. Epub 2012 Mar 4.

PMID:
22385472
10.

Evaluation of acotiamide for the treatment of functional dyspepsia.

Sun Y, Song G, McCallum RW.

Expert Opin Drug Metab Toxicol. 2014 Aug;10(8):1161-8. doi: 10.1517/17425255.2014.920320. Epub 2014 May 31. Review.

PMID:
24881488
11.

Effects of Acotiamide on the Esophageal Motility Function in Patients with Esophageal Motility Disorders: A Pilot Study.

Muta K, Ihara E, Fukaura K, Tsuchida O, Ochiai T, Nakamura K.

Digestion. 2016;94(1):9-16. doi: 10.1159/000447010. Epub 2016 Jun 22.

PMID:
27326454
12.

Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride.

Matsunaga Y, Tanaka T, Yoshinaga K, Ueki S, Hori Y, Eta R, Kawabata Y, Yoshii K, Yoshida K, Matsumura T, Furuta S, Takei M, Tack J, Itoh Z.

J Pharmacol Exp Ther. 2011 Mar;336(3):791-800. doi: 10.1124/jpet.110.174847. Epub 2010 Dec 1.

13.

A dose-ranging, placebo-controlled, pilot trial of Acotiamide in patients with functional dyspepsia.

Tack J, Masclee A, Heading R, Berstad A, Piessevaux H, Popiela T, Vandenberghe A, Kato H.

Neurogastroenterol Motil. 2009 Mar;21(3):272-80. doi: 10.1111/j.1365-2982.2009.01261.x.

PMID:
19254354
14.

Acotiamide, a new orally active acetylcholinesterase inhibitor, stimulates gastrointestinal motor activity in conscious dogs.

Nagahama K, Matsunaga Y, Kawachi M, Ito K, Tanaka T, Hori Y, Oka H, Takei M.

Neurogastroenterol Motil. 2012 Jun;24(6):566-74, e256. doi: 10.1111/j.1365-2982.2012.01912.x. Epub 2012 Mar 19.

PMID:
22429221
15.

Improvement of meal-related symptoms and epigastric pain in patients with functional dyspepsia treated with acotiamide was associated with acylated ghrelin levels in Japan.

Yamawaki H, Futagami S, Kawagoe T, Maruki Y, Hashimoto S, Nagoya H, Sato H, Kodaka Y, Gudis K, Akamizu T, Sakamoto C, Iwakiri K.

Neurogastroenterol Motil. 2016 Jul;28(7):1037-47. doi: 10.1111/nmo.12805. Epub 2016 Feb 27.

PMID:
26920949
16.

Mechanism for distribution of acotiamide, a novel gastroprokinetic agent for the treatment of functional dyspepsia, in rat stomach.

Yoshii K, Hirayama M, Nakamura T, Toda R, Hasegawa J, Takei M, Mera Y, Kawabata Y.

J Pharm Sci. 2011 Nov;100(11):4965-73. doi: 10.1002/jps.22649. Epub 2011 May 31.

PMID:
21630282
17.

Dyspepsia.

Ford AC, Moayyedi P.

Curr Opin Gastroenterol. 2013 Nov;29(6):662-8. doi: 10.1097/MOG.0b013e328365d45d. Review.

PMID:
24100727
18.

Emerging drugs for functional dyspepsia.

Zala AV, Walker MM, Talley NJ.

Expert Opin Emerg Drugs. 2015 Jun;20(2):221-33. doi: 10.1517/14728214.2015.1009827. Epub 2015 Feb 3. Review.

PMID:
25645940
19.

Clinical trial: dose-dependent therapeutic efficacy of acotiamide hydrochloride (Z-338) in patients with functional dyspepsia - 100 mg t.i.d. is an optimal dosage.

Matsueda K, Hongo M, Tack J, Aoki H, Saito Y, Kato H.

Neurogastroenterol Motil. 2010 Jun;22(6):618-e173. doi: 10.1111/j.1365-2982.2009.01449.x. Epub 2010 Jan 5.

PMID:
20059698
20.

A placebo-controlled trial of acotiamide for meal-related symptoms of functional dyspepsia.

Matsueda K, Hongo M, Tack J, Saito Y, Kato H.

Gut. 2012 Jun;61(6):821-8. doi: 10.1136/gutjnl-2011-301454. Epub 2011 Dec 9.

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