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Surface association of Pht proteins of Streptococcus pneumoniae.

Plumptre CD, Ogunniyi AD, Paton JC.

Infect Immun. 2013 Oct;81(10):3644-51. doi: 10.1128/IAI.00562-13. Epub 2013 Jul 22.


Pneumococcal histidine triad proteins are regulated by the Zn2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H.

Ogunniyi AD, Grabowicz M, Mahdi LK, Cook J, Gordon DL, Sadlon TA, Paton JC.

FASEB J. 2009 Mar;23(3):731-8. doi: 10.1096/fj.08-119537. Epub 2008 Oct 29.


Overlapping functionality of the Pht proteins in zinc homeostasis of Streptococcus pneumoniae.

Plumptre CD, Hughes CE, Harvey RM, Eijkelkamp BA, McDevitt CA, Paton JC.

Infect Immun. 2014 Oct;82(10):4315-24. doi: 10.1128/IAI.02155-14. Epub 2014 Jul 28.


Transcriptional regulation, occurrence and putative role of the Pht family of Streptococcus pneumoniae.

Rioux S, Neyt C, Di Paolo E, Turpin L, Charland N, Labbé S, Mortier MC, Mitchell TJ, Feron C, Martin D, Poolman JT.

Microbiology. 2011 Feb;157(Pt 2):336-48. doi: 10.1099/mic.0.042184-0. Epub 2010 Oct 21.


Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis.

Adamou JE, Heinrichs JH, Erwin AL, Walsh W, Gayle T, Dormitzer M, Dagan R, Brewah YA, Barren P, Lathigra R, Langermann S, Koenig S, Johnson S.

Infect Immun. 2001 Feb;69(2):949-58.


Interaction of pneumococcal histidine triad proteins with human complement.

Melin M, Di Paolo E, Tikkanen L, Jarva H, Neyt C, Käyhty H, Meri S, Poolman J, Väkeväinen M.

Infect Immun. 2010 May;78(5):2089-98. doi: 10.1128/IAI.00811-09. Epub 2010 Mar 1.


Role of Pht proteins in attachment of Streptococcus pneumoniae to respiratory epithelial cells.

Kallio A, Sepponen K, Hermand P, Denoël P, Godfroid F, Melin M.

Infect Immun. 2014 Apr;82(4):1683-91. doi: 10.1128/IAI.00699-13. Epub 2014 Feb 3.


The First Histidine Triad Motif of PhtD Is Critical for Zinc Homeostasis in Streptococcus pneumoniae.

Eijkelkamp BA, Pederick VG, Plumptre CD, Harvey RM, Hughes CE, Paton JC, McDevitt CA.

Infect Immun. 2015 Nov 16;84(2):407-15. doi: 10.1128/IAI.01082-15.


Polyhistidine triad proteins of pathogenic streptococci.

Plumptre CD, Ogunniyi AD, Paton JC.

Trends Microbiol. 2012 Oct;20(10):485-93. doi: 10.1016/j.tim.2012.06.004. Epub 2012 Jul 20. Review.


The pavA gene of Streptococcus pneumoniae encodes a fibronectin-binding protein that is essential for virulence.

Holmes AR, McNab R, Millsap KW, Rohde M, Hammerschmidt S, Mawdsley JL, Jenkinson HF.

Mol Microbiol. 2001 Sep;41(6):1395-408.


Regulation of the arginine deiminase system by ArgR2 interferes with arginine metabolism and fitness of Streptococcus pneumoniae.

Schulz C, Gierok P, Petruschka L, Lalk M, Mäder U, Hammerschmidt S.

MBio. 2014 Dec 23;5(6). pii: e01858-14. doi: 10.1128/mBio.01858-14.


A novel protein, RafX, is important for common cell wall polysaccharide biosynthesis in Streptococcus pneumoniae: implications for bacterial virulence.

Wu K, Huang J, Zhang Y, Xu W, Xu H, Wang L, Cao J, Zhang X, Yin Y.

J Bacteriol. 2014 Sep;196(18):3324-34. doi: 10.1128/JB.01696-14. Epub 2014 Jul 7.


[Effect of clpE gene deletion on virulence of Streptococcus pneumoniae].

Zhang Q, Yin N, Xu W, Wang H, Pang D, Yang X, Yin Y, Zhang X.

Wei Sheng Wu Xue Bao. 2009 Feb;49(2):233-8. Chinese.


[Influence of lysozyme-like protein on virulence and capsular polysaccharide synthesis of Streptococcus pneumoniae].

Huang J, Jiang X, Huang M, Yangi X, Liu M, Wang H, Meng J.

Wei Sheng Wu Xue Bao. 2011 Jan;51(1):59-65. Chinese.


Impact of glutamine transporters on pneumococcal fitness under infection-related conditions.

Härtel T, Klein M, Koedel U, Rohde M, Petruschka L, Hammerschmidt S.

Infect Immun. 2011 Jan;79(1):44-58. doi: 10.1128/IAI.00855-10. Epub 2010 Nov 15.


Zinc uptake by Streptococcus pneumoniae depends on both AdcA and AdcAII and is essential for normal bacterial morphology and virulence.

Bayle L, Chimalapati S, Schoehn G, Brown J, Vernet T, Durmort C.

Mol Microbiol. 2011 Nov;82(4):904-16. doi: 10.1111/j.1365-2958.2011.07862.x. Epub 2011 Oct 24.


Role played by psrP-secY2A2 (accessory region 34) in the invasive disease potential of Streptococcus pneumoniae.

Orihuela CJ.

J Infect Dis. 2009 Oct 1;200(7):1180-1; author reply 1181-2. doi: 10.1086/605649. No abstract available.


Discovery of Immunodominant B Cell Epitopes within Surface Pneumococcal Virulence Proteins in Pediatric Patients with Invasive Pneumococcal Disease.

Lagousi T, Routsias J, Piperi C, Tsakris A, Chrousos G, Theodoridou M, Spoulou V.

J Biol Chem. 2015 Nov 13;290(46):27500-10. doi: 10.1074/jbc.M115.666818. Epub 2015 Sep 22.

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