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Items: 1 to 20 of 96


Purification of native Arp2/3 complex from bovine thymus.

Doolittle LK, Rosen MK, Padrick SB.

Methods Mol Biol. 2013;1046:231-50. doi: 10.1007/978-1-62703-538-5_14.


Purification of Arp2/3 complex from Saccharomyces cerevisiae.

Doolittle LK, Rosen MK, Padrick SB.

Methods Mol Biol. 2013;1046:251-71. doi: 10.1007/978-1-62703-538-5_15.


Nucleotide- and activator-dependent structural and dynamic changes of arp2/3 complex monitored by hydrogen/deuterium exchange and mass spectrometry.

Zencheck WD, Xiao H, Nolen BJ, Angeletti RH, Pollard TD, Almo SC.

J Mol Biol. 2009 Jul 17;390(3):414-27. doi: 10.1016/j.jmb.2009.03.028. Epub 2009 Mar 17.


Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments.

LeClaire LL 3rd, Baumgartner M, Iwasa JH, Mullins RD, Barber DL.

J Cell Biol. 2008 Aug 25;182(4):647-54. doi: 10.1083/jcb.200802145.


The conformational state of actin filaments regulates branching by actin-related protein 2/3 (Arp2/3) complex.

Jensen MH, Morris EJ, Huang R, Rebowski G, Dominguez R, Weitz DA, Moore JR, Wang CL.

J Biol Chem. 2012 Sep 7;287(37):31447-53. doi: 10.1074/jbc.M112.350421. Epub 2012 Jul 12.


The structural basis of actin filament branching by the Arp2/3 complex.

Rouiller I, Xu XP, Amann KJ, Egile C, Nickell S, Nicastro D, Li R, Pollard TD, Volkmann N, Hanein D.

J Cell Biol. 2008 Mar 10;180(5):887-95. doi: 10.1083/jcb.200709092. Epub 2008 Mar 3.


Capping protein increases the rate of actin-based motility by promoting filament nucleation by the Arp2/3 complex.

Akin O, Mullins RD.

Cell. 2008 May 30;133(5):841-51. doi: 10.1016/j.cell.2008.04.011.


Three-dimensional reconstructions of actin filaments capped by Arp2/3 complex.

Volkmann N, Page C, Li R, Hanein D.

Eur J Cell Biol. 2014 May-Jun;93(5-6):179-83. doi: 10.1016/j.ejcb.2014.01.003. Epub 2014 Jan 25.


Phosphorylation of the Arp2 subunit relieves auto-inhibitory interactions for Arp2/3 complex activation.

Narayanan A, LeClaire LL 3rd, Barber DL, Jacobson MP.

PLoS Comput Biol. 2011 Nov;7(11):e1002226. doi: 10.1371/journal.pcbi.1002226. Epub 2011 Nov 10.


WAVE binds Ena/VASP for enhanced Arp2/3 complex-based actin assembly.

Havrylenko S, Noguera P, Abou-Ghali M, Manzi J, Faqir F, Lamora A, Guérin C, Blanchoin L, Plastino J.

Mol Biol Cell. 2015 Jan 1;26(1):55-65. doi: 10.1091/mbc.E14-07-1200. Epub 2014 Oct 29.


Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells.

Ilatovskaya DV, Chubinskiy-Nadezhdin V, Pavlov TS, Shuyskiy LS, Tomilin V, Palygin O, Staruschenko A, Negulyaev YA.

Cell Tissue Res. 2013 Dec;354(3):783-92. doi: 10.1007/s00441-013-1710-y. Epub 2013 Sep 15.


Cytoplasmic actin: purification and single molecule assembly assays.

Hansen SD, Zuchero JB, Mullins RD.

Methods Mol Biol. 2013;1046:145-70. doi: 10.1007/978-1-62703-538-5_9.


Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex.

Rodnick-Smith M, Luan Q, Liu SL, Nolen BJ.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3834-43. doi: 10.1073/pnas.1517798113. Epub 2016 Jun 20.


Characterization of two classes of small molecule inhibitors of Arp2/3 complex.

Nolen BJ, Tomasevic N, Russell A, Pierce DW, Jia Z, McCormick CD, Hartman J, Sakowicz R, Pollard TD.

Nature. 2009 Aug 20;460(7258):1031-4. doi: 10.1038/nature08231. Epub 2009 Aug 2.


Arp2/3 controls the motile behavior of N-WASP-functionalized GUVs and modulates N-WASP surface distribution by mediating transient links with actin filaments.

Delatour V, Helfer E, Didry D, Lê KH, Gaucher JF, Carlier MF, Romet-Lemonne G.

Biophys J. 2008 Jun;94(12):4890-905. doi: 10.1529/biophysj.107.118653. Epub 2008 Mar 7.


Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton.

Baggett AW, Cournia Z, Han MS, Patargias G, Glass AC, Liu SY, Nolen BJ.

ChemMedChem. 2012 Jul;7(7):1286-94. doi: 10.1002/cmdc.201200104. Epub 2012 May 23.


Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling.

Soderling SH.

Sci Signal. 2009 Jan 27;2(55):pe5. doi: 10.1126/scisignal.255pe5. Review.


Turnover of branched actin filament networks by stochastic fragmentation with ADF/cofilin.

Reymann AC, Suarez C, Guérin C, Martiel JL, Staiger CJ, Blanchoin L, Boujemaa-Paterski R.

Mol Biol Cell. 2011 Jul 15;22(14):2541-50. doi: 10.1091/mbc.E11-01-0052. Epub 2011 May 25.


GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism.

Ydenberg CA, Padrick SB, Sweeney MO, Gandhi M, Sokolova O, Goode BL.

Curr Biol. 2013 Jun 17;23(12):1037-45. doi: 10.1016/j.cub.2013.04.058. Epub 2013 May 30.

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